Understanding polyspecificity within the substrate-binding cavity of the human multidrug resistance P-glycoprotein.
Martinez L, Arnaud O, Henin E, Tao H, Chaptal V, Doshi R, Andrieu T, Dussurgey S, Tod M, Di Pietro A, Zhang Q, Chang G, Falson P.
Martinez L, et al. Among authors: zhang q.
FEBS J. 2014 Feb;281(3):673-82. doi: 10.1111/febs.12613. Epub 2014 Jan 17.
FEBS J. 2014.
PMID: 24219411
Free PMC article.
The X-ray structure of the mouse P-gp ortholog has been solved, with two SSS enantiomers or one RRR enantiomer of the selenohexapeptide inhibitor QZ59, found within the putative drug-binding pocket (Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Z …
The X-ray structure of the mouse P-gp ortholog has been solved, with two SSS enantiomers or one RRR enantiomer of the selenohexapeptide inhi …