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Tumor-targeting domains for chimeric antigen receptor T cells.
Bezverbnaya K, Mathews A, Sidhu J, Helsen CW, Bramson JL. Bezverbnaya K, et al. Among authors: bramson jl. Immunotherapy. 2017 Jan;9(1):33-46. doi: 10.2217/imt-2016-0103. Immunotherapy. 2017. PMID: 28000526 Review.
The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity.
Helsen CW, Hammill JA, Lau VWC, Mwawasi KA, Afsahi A, Bezverbnaya K, Newhook L, Hayes DL, Aarts C, Bojovic B, Denisova GF, Kwiecien JM, Brain I, Derocher H, Milne K, Nelson BH, Bramson JL. Helsen CW, et al. Among authors: bramson jl. Nat Commun. 2018 Aug 3;9(1):3049. doi: 10.1038/s41467-018-05395-y. Nat Commun. 2018. PMID: 30076299 Free PMC article.
TGFβ Programs Central Memory Differentiation in Ex Vivo-Stimulated Human T Cells.
Dahmani A, Janelle V, Carli C, Richaud M, Lamarche C, Khalili M, Goupil M, Bezverbnaya K, Bramson JL, Delisle JS. Dahmani A, et al. Among authors: bramson jl. Cancer Immunol Res. 2019 Sep;7(9):1426-1439. doi: 10.1158/2326-6066.CIR-18-0691. Epub 2019 Jul 15. Cancer Immunol Res. 2019. PMID: 31308016
A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.
Hammill JA, Kwiecien JM, Dvorkin-Gheva A, Lau VWC, Baker C, Wu Y, Bezverbnaya K, Aarts C, Heslen CW, Denisova GF, Derocher H, Milne K, Nelson BH, Bramson JL. Hammill JA, et al. Among authors: bramson jl. Mol Ther Oncolytics. 2020 Apr 14;17:278-292. doi: 10.1016/j.omto.2020.04.001. eCollection 2020 Jun 26. Mol Ther Oncolytics. 2020. PMID: 32368616 Free PMC article.
The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma.
Vora P, Venugopal C, Salim SK, Tatari N, Bakhshinyan D, Singh M, Seyfrid M, Upreti D, Rentas S, Wong N, Williams R, Qazi MA, Chokshi C, Ding A, Subapanditha M, Savage N, Mahendram S, Ford E, Adile AA, McKenna D, McFarlane N, Huynh V, Wylie RG, Pan J, Bramson J, Hope K, Moffat J, Singh S. Vora P, et al. Cell Stem Cell. 2020 Jun 4;26(6):832-844.e6. doi: 10.1016/j.stem.2020.04.008. Epub 2020 May 27. Cell Stem Cell. 2020. PMID: 32464096 Free article.
162 results