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Programmed mitophagy is essential for the glycolytic switch during cell differentiation.
Esteban-Martínez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Mariño G, Seco E, Durand S, Enot D, Graña O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P. Esteban-Martínez L, et al. Among authors: grana o. EMBO J. 2017 Jun 14;36(12):1688-1706. doi: 10.15252/embj.201695916. Epub 2017 May 2. EMBO J. 2017. PMID: 28465321 Free PMC article.
Telomeric RNAs are essential to maintain telomeres.
Montero JJ, López de Silanes I, Graña O, Blasco MA. Montero JJ, et al. Among authors: grana o. Nat Commun. 2016 Aug 17;7:12534. doi: 10.1038/ncomms12534. Nat Commun. 2016. PMID: 27531349 Free PMC article.
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.
Djurec M, Graña O, Lee A, Troulé K, Espinet E, Cabras L, Navas C, Blasco MT, Martín-Díaz L, Burdiel M, Li J, Liu Z, Vallespinós M, Sanchez-Bueno F, Sprick MR, Trumpp A, Sainz B Jr, Al-Shahrour F, Rabadan R, Guerra C, Barbacid M. Djurec M, et al. Among authors: grana o. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1147-E1156. doi: 10.1073/pnas.1717802115. Epub 2018 Jan 19. Proc Natl Acad Sci U S A. 2018. PMID: 29351990 Free PMC article.
Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.
Simón-Carrasco L, Graña O, Salmón M, Jacob HKC, Gutierrez A, Jiménez G, Drosten M, Barbacid M. Simón-Carrasco L, et al. Among authors: grana o. Genes Dev. 2017 Jul 15;31(14):1456-1468. doi: 10.1101/gad.300244.117. Epub 2017 Aug 21. Genes Dev. 2017. PMID: 28827401 Free PMC article.
Reprogramming in vivo produces teratomas and iPS cells with totipotency features.
Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M. Abad M, et al. Among authors: grana o. Nature. 2013 Oct 17;502(7471):340-5. doi: 10.1038/nature12586. Epub 2013 Sep 11. Nature. 2013. PMID: 24025773
Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine.
Olmeda D, Cerezo-Wallis D, Riveiro-Falkenbach E, Pennacchi PC, Contreras-Alcalde M, Ibarz N, Cifdaloz M, Catena X, Calvo TG, Cañón E, Alonso-Curbelo D, Suarez J, Osterloh L, Graña O, Mulero F, Megías D, Cañamero M, Martínez-Torrecuadrada JL, Mondal C, Di Martino J, Lora D, Martinez-Corral I, Bravo-Cordero JJ, Muñoz J, Puig S, Ortiz-Romero P, Rodriguez-Peralto JL, Ortega S, Soengas MS. Olmeda D, et al. Among authors: grana o. Nature. 2017 Jun 28;546(7660):676-680. doi: 10.1038/nature22977. Nature. 2017. PMID: 28658220 Free PMC article.
43 results