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Negative feedback loop of autophagy and endoplasmic reticulum stress in rapamycin protection against renal ischemia-reperfusion injury during initial reperfusion phase.
Li X, Zhu G, Gou X, He W, Yin H, Yang X, Li J. Li X, et al. Among authors: yin h. FASEB J. 2018 May 17:fj201800299R. doi: 10.1096/fj.201800299R. Online ahead of print. FASEB J. 2018. PMID: 29771603
As such, we designed this study to explore the potential effects and mechanisms of rapamycin under a specific therapeutic regimen in which rapamycin is mixed in the perfusate during the initial reperfusion phase (within 24 h). Interestingly, we found that rapamycin maintai …
As such, we designed this study to explore the potential effects and mechanisms of rapamycin under a specific therapeutic regimen in which r …
BMSCs protect against renal ischemia-reperfusion injury by secreting exosomes loaded with miR-199a-5p that target BIP to inhibit endoplasmic reticulum stress at the very early reperfusion stages.
Wang C, Zhu G, He W, Yin H, Lin F, Gou X, Li X. Wang C, et al. Among authors: yin h. FASEB J. 2019 Apr;33(4):5440-5456. doi: 10.1096/fj.201801821R. Epub 2019 Jan 14. FASEB J. 2019. PMID: 30640521
Impressively, our study is the first to find that BMexos protected against renal I/R injury in vitro and in vivo at the very early reperfusion stages, especially 4-8 h after reperfusion in vitro and 8-16 h after reperfusion in vivo. ...These results suggest a novel …
Impressively, our study is the first to find that BMexos protected against renal I/R injury in vitro and in vivo at the very early reperfusi …
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