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Mutant cartilage oligomeric matrix protein (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis.
Coustry F, Posey KL, Maerz T, Baker K, Abraham AM, Ambrose CG, Nobakhti S, Shefelbine SJ, Bi X, Newton M, Gawronski K, Remer L, Veerisetty AC, Hossain MG, Chiu F, Hecht JT. Coustry F, et al. Among authors: shefelbine sj. Matrix Biol. 2018 Apr;67:75-89. doi: 10.1016/j.matbio.2017.12.014. Epub 2018 Jan 5. Matrix Biol. 2018. PMID: 29309831 Free PMC article.
Characterization of the MPS I-H knock-in mouse reveals increased femoral biomechanical integrity with compromised material strength and altered bone geometry.
Oestreich AK, Garcia MR, Yao X, Pfeiffer FM, Nobakhti S, Shefelbine SJ, Wang Y, Brodeur AC, Phillips CL. Oestreich AK, et al. Among authors: shefelbine sj. Mol Genet Metab Rep. 2015 Sep 7;5:3-11. doi: 10.1016/j.ymgmr.2015.08.004. eCollection 2015 Dec. Mol Genet Metab Rep. 2015. PMID: 28649535 Free PMC article.
Osteopontin regulates type I collagen fibril formation in bone tissue.
Depalle B, McGilvery CM, Nobakhti S, Aldegaither N, Shefelbine SJ, Porter AE. Depalle B, et al. Among authors: shefelbine sj. Acta Biomater. 2021 Jan 15;120:194-202. doi: 10.1016/j.actbio.2020.04.040. Epub 2020 Apr 25. Acta Biomater. 2021. PMID: 32344173 Free PMC article.
Bone mechanical properties and changes with osteoporosis.
Osterhoff G, Morgan EF, Shefelbine SJ, Karim L, McNamara LM, Augat P. Osterhoff G, et al. Among authors: shefelbine sj. Injury. 2016 Jun;47 Suppl 2(Suppl 2):S11-20. doi: 10.1016/S0020-1383(16)47003-8. Injury. 2016. PMID: 27338221 Free PMC article. Review.
Counteracting bone fragility with human amniotic mesenchymal stem cells.
Ranzoni AM, Corcelli M, Hau KL, Kerns JG, Vanleene M, Shefelbine S, Jones GN, Moschidou D, Dala-Ali B, Goodship AE, De Coppi P, Arnett TR, Guillot PV. Ranzoni AM, et al. Sci Rep. 2016 Dec 20;6:39656. doi: 10.1038/srep39656. Sci Rep. 2016. PMID: 27995994 Free PMC article.
How tough is brittle bone? Investigating osteogenesis imperfecta in mouse bone.
Carriero A, Zimmermann EA, Paluszny A, Tang SY, Bale H, Busse B, Alliston T, Kazakia G, Ritchie RO, Shefelbine SJ. Carriero A, et al. Among authors: shefelbine sj. J Bone Miner Res. 2014 Jun;29(6):1392-1401. doi: 10.1002/jbmr.2172. J Bone Miner Res. 2014. PMID: 24420672 Free PMC article.
124 results