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A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis.
Tong D, Lönnblom E, Yau ACY, Nandakumar KS, Liang B, Ge C, Viljanen J, Li L, Bãlan M, Klareskog L, Chagin AS, Gjertsson I, Kihlberg J, Zhao M, Holmdahl R. Tong D, et al. Among authors: chagin as. Front Immunol. 2018 Apr 12;9:451. doi: 10.3389/fimmu.2018.00451. eCollection 2018. Front Immunol. 2018. PMID: 29706949 Free PMC article.
Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice.
Li L, Newton PT, Bouderlique T, Sejnohova M, Zikmund T, Kozhemyakina E, Xie M, Krivanek J, Kaiser J, Qian H, Dyachuk V, Lassar AB, Warman ML, Barenius B, Adameyko I, Chagin AS. Li L, et al. Among authors: chagin as. FASEB J. 2017 Mar;31(3):1067-1084. doi: 10.1096/fj.201600918R. Epub 2016 Dec 13. FASEB J. 2017. PMID: 27965322 Free PMC article.
Quantitative analysis of cellular kinetics, in combination with phosphotungstic acid-enhanced micro-computed tomography, showed that superficial cells generate chondrocytes and contribute to the growth and reshaping of articular cartilage. Furthermore, we found that cartilage ren …
Quantitative analysis of cellular kinetics, in combination with phosphotungstic acid-enhanced micro-computed tomography, showed that superfi …
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.
Kaucka M, Zikmund T, Tesarova M, Gyllborg D, Hellander A, Jaros J, Kaiser J, Petersen J, Szarowska B, Newton PT, Dyachuk V, Li L, Qian H, Johansson AS, Mishina Y, Currie JD, Tanaka EM, Erickson A, Dudley A, Brismar H, Southam P, Coen E, Chen M, Weinstein LS, Hampl A, Arenas E, Chagin AS, Fried K, Adameyko I. Kaucka M, et al. Among authors: chagin as. Elife. 2017 Apr 17;6:e25902. doi: 10.7554/eLife.25902. Elife. 2017. PMID: 28414273 Free PMC article.
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.
Newton PT, Li L, Zhou B, Schweingruber C, Hovorakova M, Xie M, Sun X, Sandhow L, Artemov AV, Ivashkin E, Suter S, Dyachuk V, El Shahawy M, Gritli-Linde A, Bouderlique T, Petersen J, Mollbrink A, Lundeberg J, Enikolopov G, Qian H, Fried K, Kasper M, Hedlund E, Adameyko I, Sävendahl L, Chagin AS. Newton PT, et al. Among authors: chagin as. Nature. 2019 Mar;567(7747):234-238. doi: 10.1038/s41586-019-0989-6. Epub 2019 Feb 27. Nature. 2019. PMID: 30814736
Secondary ossification center induces and protects growth plate structure.
Xie M, Gol'din P, Herdina AN, Estefa J, Medvedeva EV, Li L, Newton PT, Kotova S, Shavkuta B, Saxena A, Shumate LT, Metscher BD, Großschmidt K, Nishimori S, Akovantseva A, Usanova AP, Kurenkova AD, Kumar A, Arregui IL, Tafforeau P, Fried K, Carlström M, Simon A, Gasser C, Kronenberg HM, Bastepe M, Cooper KL, Timashev P, Sanchez S, Adameyko I, Eriksson A, Chagin AS. Xie M, et al. Among authors: chagin as. Elife. 2020 Oct 16;9:e55212. doi: 10.7554/eLife.55212. Elife. 2020. PMID: 33063669 Free PMC article.
68 results