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Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide.
Nat Chem. 2018 Jul;10(7):787-794. doi: 10.1038/s41557-018-0055-2. Epub 2018 May 14.
Nat Chem. 2018.
PMID: 29760413
Free PMC article.
Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels-Alder Reaction.
Ji X, Zhou C, Ji K, Aghoghovbia RE, Pan Z, Chittavong V, Ke B, Wang B.
Ji X, et al. Among authors: chittavong v.
Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15846-15851. doi: 10.1002/anie.201608732. Epub 2016 Nov 23.
Angew Chem Int Ed Engl. 2016.
PMID: 27879021
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Organic CO Prodrugs: Structure-CO-Release Rate Relationship Studies.
Pan Z, Chittavong V, Li W, Zhang J, Ji K, Zhu M, Ji X, Wang B.
Pan Z, et al. Among authors: chittavong v.
Chemistry. 2017 Jul 21;23(41):9838-9845. doi: 10.1002/chem.201700936. Epub 2017 Jul 4.
Chemistry. 2017.
PMID: 28544290
Free PMC article.
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An esterase-activated click and release approach to metal-free CO-prodrugs.
Ji X, Ji K, Chittavong V, Yu B, Pan Z, Wang B.
Ji X, et al. Among authors: chittavong v.
Chem Commun (Camb). 2017 Jul 20;53(59):8296-8299. doi: 10.1039/c7cc03832a.
Chem Commun (Camb). 2017.
PMID: 28685779
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pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates.
Ji X, De La Cruz LKC, Pan Z, Chittavong V, Wang B.
Ji X, et al. Among authors: chittavong v.
Chem Commun (Camb). 2017 Aug 24;53(69):9628-9631. doi: 10.1039/c7cc04866a.
Chem Commun (Camb). 2017.
PMID: 28809970
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Organic CO Prodrugs Activated by Endogenous ROS.
Pan Z, Zhang J, Ji K, Chittavong V, Ji X, Wang B.
Pan Z, et al. Among authors: chittavong v.
Org Lett. 2018 Jan 5;20(1):8-11. doi: 10.1021/acs.orglett.7b02775. Epub 2017 Nov 7.
Org Lett. 2018.
PMID: 29111756
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Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide.
Zheng Y, Yu B, Ji K, Pan Z, Chittavong V, Wang B.
Zheng Y, et al. Among authors: chittavong v.
Angew Chem Int Ed Engl. 2016 Mar 24;55(14):4514-8. doi: 10.1002/anie.201511244. Epub 2016 Jan 28.
Angew Chem Int Ed Engl. 2016.
PMID: 26822005
Free PMC article.
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Click and Fluoresce: A Bioorthogonally Activated Smart Probe for Wash-Free Fluorescent Labeling of Biomolecules.
Ji X, Ji K, Chittavong V, Aghoghovbia RE, Zhu M, Wang B.
Ji X, et al. Among authors: chittavong v.
J Org Chem. 2017 Feb 3;82(3):1471-1476. doi: 10.1021/acs.joc.6b02654. Epub 2017 Jan 23.
J Org Chem. 2017.
PMID: 28067514
Free PMC article.
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