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Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a double-blind, randomised withdrawal phase.
Pivonello R, Fleseriu M, Newell-Price J, Bertagna X, Findling J, Shimatsu A, Gu F, Auchus R, Leelawattana R, Lee EJ, Kim JH, Lacroix A, Laplanche A, O'Connell P, Tauchmanova L, Pedroncelli AM, Biller BMK; LINC 3 investigators. Pivonello R, et al. Lancet Diabetes Endocrinol. 2020 Sep;8(9):748-761. doi: 10.1016/S2213-8587(20)30240-0. Epub 2020 Jul 27. Lancet Diabetes Endocrinol. 2020. PMID: 32730798 Clinical Trial.
Association between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective, multicentre, observational cohort study in 1210 patients from the Collaborative Islet Transplant Registry.
Chetboun M, Drumez E, Ballou C, Maanaoui M, Payne E, Barton F, Kerr-Conte J, Vantyghem MC, Piemonti L, Rickels MR, Labreuche J, Pattou F; Collaborative Islet Transplant Registry (CITR) Investigators study group. Chetboun M, et al. Lancet Diabetes Endocrinol. 2023 Jun;11(6):391-401. doi: 10.1016/S2213-8587(23)00082-7. Epub 2023 Apr 24. Lancet Diabetes Endocrinol. 2023. PMID: 37105208 Free PMC article.
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease.
Pan Z, El Sharkway R, Bayoumi A, Metwally M, Gloss BS, Brink R, Lu DB, Liddle C, Alqahtani SA, Yu J, O'Connell PJ, George J, Eslam M. Pan Z, et al. Among authors: o connell pj. Sci Transl Med. 2024 Apr 3;16(741):eadj0133. doi: 10.1126/scitranslmed.adj0133. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569018
Intragraft memory-like CD127hiCD4+Foxp3+ Tregs maintain transplant tolerance.
Zhao Y, Nicholson L, Wang H, Qian YW, Hawthorne WJ, Jimenez-Vera E, Gloss BS, Lai J, Thomas A, Chew YV, Burns H, Zhang GY, Wang YM, Rogers NM, Zheng G, Yi S, Alexander SI, O'Connell PJ, Hu M. Zhao Y, et al. Among authors: o connell pj. JCI Insight. 2024 Feb 13;9(6):e169119. doi: 10.1172/jci.insight.169119. JCI Insight. 2024. PMID: 38516885 Free PMC article.
1,007 results