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Heart neurons use clock genes to control myocyte proliferation.
Tampakakis E, Gangrade H, Glavaris S, Htet M, Murphy S, Lin BL, Liu T, Saberi A, Miyamoto M, Kowalski W, Mukouyama YS, Lee G, Minichiello L, Kwon C. Tampakakis E, et al. Among authors: murphy s. Sci Adv. 2021 Dec 3;7(49):eabh4181. doi: 10.1126/sciadv.abh4181. Epub 2021 Dec 1. Sci Adv. 2021. PMID: 34851661 Free PMC article.
Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.
Cho GS, Lee DI, Tampakakis E, Murphy S, Andersen P, Uosaki H, Chelko S, Chakir K, Hong I, Seo K, Chen HV, Chen X, Basso C, Houser SR, Tomaselli GF, O'Rourke B, Judge DP, Kass DA, Kwon C. Cho GS, et al. Among authors: murphy s. Cell Rep. 2017 Jan 10;18(2):571-582. doi: 10.1016/j.celrep.2016.12.040. Cell Rep. 2017. PMID: 28076798 Free PMC article.
Precardiac organoids form two heart fields via Bmp/Wnt signaling.
Andersen P, Tampakakis E, Jimenez DV, Kannan S, Miyamoto M, Shin HK, Saberi A, Murphy S, Sulistio E, Chelko SP, Kwon C. Andersen P, et al. Among authors: murphy s. Nat Commun. 2018 Aug 7;9(1):3140. doi: 10.1038/s41467-018-05604-8. Nat Commun. 2018. PMID: 30087351 Free PMC article.
PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2.
Murphy SA, Miyamoto M, Kervadec A, Kannan S, Tampakakis E, Kambhampati S, Lin BL, Paek S, Andersen P, Lee DI, Zhu R, An SS, Kass DA, Uosaki H, Colas AR, Kwon C. Murphy SA, et al. Nat Commun. 2021 Mar 12;12(1):1648. doi: 10.1038/s41467-021-21957-z. Nat Commun. 2021. PMID: 33712605 Free PMC article.
Noncanonical Notch signals have opposing roles during cardiac development.
Miyamoto M, Andersen P, Sulistio E, Liu X, Murphy S, Kannan S, Nam L, Miyamoto W, Tampakakis E, Hibino N, Uosaki H, Kwon C. Miyamoto M, et al. Among authors: murphy s. Biochem Biophys Res Commun. 2021 Nov 5;577:12-16. doi: 10.1016/j.bbrc.2021.08.094. Epub 2021 Sep 2. Biochem Biophys Res Commun. 2021. PMID: 34487959 Free PMC article.
Cardiac progenitors instruct second heart field fate through Wnts.
Miyamoto M, Kannan S, Anderson MJ, Liu X, Suh D, Htet M, Li B, Kakani T, Murphy S, Tampakakis E, Lewandoski M, Andersen P, Uosaki H, Kwon C. Miyamoto M, et al. Among authors: murphy s. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217687120. doi: 10.1073/pnas.2217687120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649430 Free PMC article.
Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells.
Missinato MA, Murphy S, Lynott M, Yu MS, Kervadec A, Chang YL, Kannan S, Loreti M, Lee C, Amatya P, Tanaka H, Huang CT, Puri PL, Kwon C, Adams PD, Qian L, Sacco A, Andersen P, Colas AR. Missinato MA, et al. Among authors: murphy s. Nat Commun. 2023 Mar 27;14(1):1709. doi: 10.1038/s41467-023-37256-8. Nat Commun. 2023. PMID: 36973293 Free PMC article.
5,779 results