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Mast cell-derived factor XIIIA contributes to sexual dimorphic defense against group B streptococcal infections.
Piliponsky AM, Sharma K, Quach P, Brokaw A, Nguyen S, Orvis A, Saha SS, Samanas NB, Seepersaud R, Tang YP, Mackey E, Bhise G, Gendrin C, Furuta A, Seo AJ, Guga E, Miralda I, Coleman M, Sweeney EL, Bäuml CA, Imhof D, Snyder JM, Moeser AJ, Rajagopal L. Piliponsky AM, et al. J Clin Invest. 2022 Oct 17;132(20):e157999. doi: 10.1172/JCI157999. J Clin Invest. 2022. PMID: 36006736 Free PMC article.
Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.
Shubin NJ, Glukhova VA, Clauson M, Truong P, Abrink M, Pejler G, White NJ, Deutsch GH, Reeves SR, Vaisar T, James RG, Piliponsky AM. Shubin NJ, et al. Among authors: piliponsky am. J Allergy Clin Immunol. 2017 Jan;139(1):323-334. doi: 10.1016/j.jaci.2016.03.051. Epub 2016 May 13. J Allergy Clin Immunol. 2017. PMID: 27302551 Free PMC article.
Mast cell chymase decreases the severity of group B Streptococcus infections.
Gendrin C, Shubin NJ, Boldenow E, Merillat S, Clauson M, Power D, Doran KS, Abrink M, Pejler G, Rajagopal L, Piliponsky AM. Gendrin C, et al. Among authors: piliponsky am. J Allergy Clin Immunol. 2018 Jul;142(1):120-129.e6. doi: 10.1016/j.jaci.2017.07.042. Epub 2017 Sep 12. J Allergy Clin Immunol. 2018. PMID: 28916188 Free PMC article.
Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition.
Shubin NJ, Clauson M, Niino K, Kasprzak V, Tsuha A, Guga E, Bhise G, Acharya M, Snyder JM, Debley JS, Ziegler SF, Piliponsky AM. Shubin NJ, et al. Among authors: piliponsky am. Mucosal Immunol. 2020 Jul;13(4):584-594. doi: 10.1038/s41385-020-0271-0. Epub 2020 Feb 26. Mucosal Immunol. 2020. PMID: 32103153 Free PMC article.
Siglec-9 is an inhibitory receptor on human mast cells in vitro.
Miralda I, Samanas NB, Seo AJ, Foronda JS, Sachen J, Hui Y, Morrison SD, Oskeritzian CA, Piliponsky AM. Miralda I, et al. Among authors: piliponsky am. J Allergy Clin Immunol. 2023 Sep;152(3):711-724.e14. doi: 10.1016/j.jaci.2023.04.007. Epub 2023 Apr 24. J Allergy Clin Immunol. 2023. PMID: 37100120 Free PMC article.
Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.
Lai Y, Altemeier WA, Vandree J, Piliponsky AM, Johnson B, Appel CL, Frevert CW, Hyde DM, Ziegler SF, Smith DE, Henderson WR Jr, Gelb MH, Hallstrand TS. Lai Y, et al. Among authors: piliponsky am. J Allergy Clin Immunol. 2014 May;133(5):1448-55. doi: 10.1016/j.jaci.2013.08.052. Epub 2013 Nov 9. J Allergy Clin Immunol. 2014. PMID: 24220317 Free PMC article. Clinical Trial.
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