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H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
Haase S, Banerjee K, Mujeeb AA, Hartlage CS, Núñez FM, Núñez FJ, Alghamri MS, Kadiyala P, Carney S, Barissi MN, Taher AW, Brumley EK, Thompson S, Dreyer JT, Alindogan CT, Garcia-Fabiani MB, Comba A, Venneti S, Ravikumar V, Koschmann C, Carcaboso ÁM, Vinci M, Rao A, Yu JS, Lowenstein PR, Castro MG. Haase S, et al. Among authors: ravikumar v. J Clin Invest. 2022 Nov 15;132(22):e154229. doi: 10.1172/JCI154229. J Clin Invest. 2022. PMID: 36125896 Free PMC article.
Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism.
Zhou X, He C, Ren J, Dai C, Stevens SR, Wang Q, Zamler D, Shingu T, Yuan L, Chandregowda CR, Wang Y, Ravikumar V, Rao AU, Zhou F, Zheng H, Rasband MN, Chen Y, Lan F, Heimberger AB, Segal BM, Hu J. Zhou X, et al. Among authors: ravikumar v. J Clin Invest. 2020 May 1;130(5):2220-2236. doi: 10.1172/JCI131800. J Clin Invest. 2020. PMID: 32202512 Free PMC article.
Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.
Sweha SR, Chung C, Natarajan SK, Panwalkar P, Pun M, Ghali A, Bayliss J, Pratt D, Shankar A, Ravikumar V, Rao A, Cieslik M, Wilder-Romans K, Scott AJ, Wahl DR, Jessa S, Kleinman CL, Jabado N, Mackay A, Jones C, Martinez D, Santi M, Judkins AR, Yadav VN, Qin T, Phoenix TN, Koschmann CJ, Baker SJ, Chinnaiyan AM, Venneti S. Sweha SR, et al. Among authors: ravikumar v. Sci Transl Med. 2021 Oct 13;13(615):eabf7860. doi: 10.1126/scitranslmed.abf7860. Epub 2021 Oct 13. Sci Transl Med. 2021. PMID: 34644147 Free PMC article.
Engineered 3D Model of Cancer Stem Cell Enrichment and Chemoresistance.
Ward Rashidi MR, Mehta P, Bregenzer M, Raghavan S, Fleck EM, Horst EN, Harissa Z, Ravikumar V, Brady S, Bild A, Rao A, Buckanovich RJ, Mehta G. Ward Rashidi MR, et al. Among authors: ravikumar v. Neoplasia. 2019 Aug;21(8):822-836. doi: 10.1016/j.neo.2019.06.005. Epub 2019 Jul 9. Neoplasia. 2019. PMID: 31299607 Free PMC article.
RNA-seq of human T cells after hematopoietic stem cell transplantation identifies Linc00402 as a regulator of T cell alloimmunity.
Peltier D, Radosevich M, Ravikumar V, Pitchiaya S, Decoville T, Wood SC, Hou G, Zajac C, Oravecz-Wilson K, Sokol D, Henig I, Wu J, Kim S, Taylor A, Fujiwara H, Sun Y, Rao A, Chinnaiyan AM, Goldstein DR, Reddy P. Peltier D, et al. Among authors: ravikumar v. Sci Transl Med. 2021 Mar 17;13(585):eaaz0316. doi: 10.1126/scitranslmed.aaz0316. Sci Transl Med. 2021. PMID: 33731431 Free PMC article.
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
Al-Holou WN, Wang H, Ravikumar V, Shankar S, Oneka M, Fehmi Z, Verhaak RG, Kim H, Pratt D, Camelo-Piragua S, Speers C, Wahl DR, Hollon T, Sagher O, Heth JA, Muraszko KM, Lawrence TS, de Carvalho AC, Mikkelsen T, Rao A, Rehemtulla A. Al-Holou WN, et al. Among authors: ravikumar v. Neoplasia. 2023 Feb;36:100872. doi: 10.1016/j.neo.2022.100872. Epub 2023 Jan 6. Neoplasia. 2023. PMID: 36621024 Free PMC article.
Metabolomic Profiles of Human Glioma Inform Patient Survival.
Scott AJ, Correa LO, Edwards DM, Sun Y, Ravikumar V, Andren AC, Zhang L, Srinivasan S, Jairath N, Verbal K, Muraszko K, Sagher O, Carty SA, Hervey-Jumper S, Orringer D, Kim MM, Junck L, Umemura Y, Leung D, Venneti S, Camelo-Piragua S, Lawrence TS, Ippolito JE, Al-Holou WN, Chinnaiyan P, Heth J, Rao A, Lyssiotis CA, Wahl DR. Scott AJ, et al. Among authors: ravikumar v. Antioxid Redox Signal. 2023 Nov;39(13-15):942-956. doi: 10.1089/ars.2022.0085. Epub 2023 Apr 27. Antioxid Redox Signal. 2023. PMID: 36852494 Review.
LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function.
Kumaraswamy A, Duan Z, Flores D, Zhang C, Sehrawat A, Hu YM, Swaim OA, Rodansky E, Storck WK, Kuleape JA, Bedi K, Mannan R, Wang XM, Udager A, Ravikumar V, Bankhead A 3rd, Coleman I, Lee JK, Morrissey C, Nelson PS, Chinnaiyan AM, Rao A, Xia Z, Yates JA, Alumkal JJ. Kumaraswamy A, et al. Among authors: ravikumar v. JCI Insight. 2023 Aug 8;8(15):e167440. doi: 10.1172/jci.insight.167440. JCI Insight. 2023. PMID: 37440313 Free PMC article.
Multiple-response regression analysis links magnetic resonance imaging features to de-regulated protein expression and pathway activity in lower grade glioma.
Lehrer M, Bhadra A, Ravikumar V, Chen JY, Wintermark M, Hwang SN, Holder CA, Huang EP, Fevrier-Sullivan B, Freymann JB, Rao A; TCGA Glioma Phenotype Research Group. Lehrer M, et al. Among authors: ravikumar v. Oncoscience. 2017 Jun 23;4(5-6):57-66. doi: 10.18632/oncoscience.353. eCollection 2017 May. Oncoscience. 2017. PMID: 28781988 Free PMC article.
195 results