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GPR114/ADGRG5 is activated by its tethered peptide agonist because it is a cleaved adhesion GPCR.
J Biol Chem. 2023 Oct;299(10):105223. doi: 10.1016/j.jbc.2023.105223. Epub 2023 Sep 9.
J Biol Chem. 2023.
PMID: 37673336
Free PMC article.
Mechanisms of adhesion G protein-coupled receptor activation.
Vizurraga A, Adhikari R, Yeung J, Yu M, Tall GG.
Vizurraga A, et al.
J Biol Chem. 2020 Oct 9;295(41):14065-14083. doi: 10.1074/jbc.REV120.007423. Epub 2020 Aug 6.
J Biol Chem. 2020.
PMID: 32763969
Free PMC article.
Review.
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G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3.
Mathiasen S, Palmisano T, Perry NA, Stoveken HM, Vizurraga A, McEwen DP, Okashah N, Langenhan T, Inoue A, Lambert NA, Tall GG, Javitch JA.
Mathiasen S, et al. Among authors: vizurraga a.
Nat Chem Biol. 2020 Dec;16(12):1343-1350. doi: 10.1038/s41589-020-0617-7. Epub 2020 Aug 10.
Nat Chem Biol. 2020.
PMID: 32778842
Free PMC article.
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The tethered peptide activation mechanism of adhesion GPCRs.
Barros-Álvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG, Shalev-Benami M, Tall GG, Skiniotis G.
Barros-Álvarez X, et al. Among authors: vizurraga a.
Nature. 2022 Apr;604(7907):757-762. doi: 10.1038/s41586-022-04575-7. Epub 2022 Apr 13.
Nature. 2022.
PMID: 35418682
Free PMC article.
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Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56.
Vizurraga AL, Robertson MJ, Yu M, Skiniotis G, Tall GG.
Vizurraga AL, et al.
Mol Pharmacol. 2023 Jul;104(1):28-41. doi: 10.1124/molpharm.123.000688. Epub 2023 Jun 8.
Mol Pharmacol. 2023.
PMID: 37290962
Free PMC article.
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Publisher Correction: G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3.
Mathiasen S, Palmisano T, Perry NA, Stoveken HM, Vizurraga A, McEwen DP, Okashah N, Langenhan T, Inoue A, Lambert NA, Tall GG, Javitch JA.
Mathiasen S, et al. Among authors: vizurraga a.
Nat Chem Biol. 2020 Dec;16(12):1440. doi: 10.1038/s41589-020-0649-z.
Nat Chem Biol. 2020.
PMID: 32807971
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GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force.
Yeung J, Adili R, Stringham EN, Luo R, Vizurraga A, Rosselli-Murai LK, Stoveken HM, Yu M, Piao X, Holinstat M, Tall GG.
Yeung J, et al. Among authors: vizurraga a.
Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28275-28286. doi: 10.1073/pnas.2008921117. Epub 2020 Oct 23.
Proc Natl Acad Sci U S A. 2020.
PMID: 33097663
Free PMC article.
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Parasite Manipulation of Its Host's Physiological Reaction to Acute Stress: Experimental Results from a Natural Beetle-Nematode System.
Davis AK, Vasquez D, LeFeuvre J, Sims S, Craft M, Vizurraga A.
Davis AK, et al. Among authors: vizurraga a.
Physiol Biochem Zool. 2017 Mar/Apr;90(2):273-280. doi: 10.1086/689301. Epub 2016 Nov 11.
Physiol Biochem Zool. 2017.
PMID: 28277955
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