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Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data.
Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, Chawla DG, Soares-Schanoski A, Spurbeck RR, Ndhlovu LC, Sebra R, Kleinstein SH, Letizia AG, Ramos I, Fowler VG Jr, Woods CW, Zaslavsky E, Troyanskaya OG, Sealfon SC. Chen X, et al. Among authors: troyanskaya og. Nat Comput Sci. 2023 Jul;3(7):644-657. doi: 10.1038/s43588-023-00476-5. Epub 2023 Jul 25. Nat Comput Sci. 2023. PMID: 37974651 Free PMC article.
Discovery of biological networks from diverse functional genomic data.
Myers CL, Robson D, Wible A, Hibbs MA, Chiriac C, Theesfeld CL, Dolinski K, Troyanskaya OG. Myers CL, et al. Among authors: troyanskaya og. Genome Biol. 2005;6(13):R114. doi: 10.1186/gb-2005-6-13-r114. Epub 2005 Dec 19. Genome Biol. 2005. PMID: 16420673 Free PMC article.
Targeted exploration and analysis of large cross-platform human transcriptomic compendia.
Zhu Q, Wong AK, Krishnan A, Aure MR, Tadych A, Zhang R, Corney DC, Greene CS, Bongo LA, Kristensen VN, Charikar M, Li K, Troyanskaya OG. Zhu Q, et al. Among authors: troyanskaya og. Nat Methods. 2015 Mar;12(3):211-4, 3 p following 214. doi: 10.1038/nmeth.3249. Epub 2015 Jan 12. Nat Methods. 2015. PMID: 25581801 Free PMC article.
Low-variance RNAs identify Parkinson's disease molecular signature in blood.
Chikina MD, Gerald CP, Li X, Ge Y, Pincas H, Nair VD, Wong AK, Krishnan A, Troyanskaya OG, Raymond D, Saunders-Pullman R, Bressman SB, Yue Z, Sealfon SC. Chikina MD, et al. Among authors: troyanskaya og. Mov Disord. 2015 May;30(6):813-21. doi: 10.1002/mds.26205. Epub 2015 Mar 18. Mov Disord. 2015. PMID: 25786808 Free PMC article.
Understanding multicellular function and disease with human tissue-specific networks.
Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC, Chasman DI, FitzGerald GA, Dolinski K, Grosser T, Troyanskaya OG. Greene CS, et al. Among authors: troyanskaya og. Nat Genet. 2015 Jun;47(6):569-76. doi: 10.1038/ng.3259. Epub 2015 Apr 27. Nat Genet. 2015. PMID: 25915600 Free PMC article.
Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases.
Gorenshteyn D, Zaslavsky E, Fribourg M, Park CY, Wong AK, Tadych A, Hartmann BM, Albrecht RA, García-Sastre A, Kleinstein SH, Troyanskaya OG, Sealfon SC. Gorenshteyn D, et al. Among authors: troyanskaya og. Immunity. 2015 Sep 15;43(3):605-14. doi: 10.1016/j.immuni.2015.08.014. Epub 2015 Sep 8. Immunity. 2015. PMID: 26362267 Free PMC article.
167 results