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Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling.
Chui JS, Izuel-Idoype T, Qualizza A, de Almeida RP, Piessens L, van der Veer BK, Vanmarcke G, Malesa A, Athanasouli P, Boon R, Vriens J, van Grunsven L, Koh KP, Verfaillie CM, Lluis F. Chui JS, et al. Among authors: van grunsven l. Adv Sci (Weinh). 2024 Feb;11(7):e2307554. doi: 10.1002/advs.202307554. Epub 2023 Dec 1. Adv Sci (Weinh). 2024. PMID: 38037844 Free PMC article.
Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis.
Coll M, Perea L, Boon R, Leite SB, Vallverdú J, Mannaerts I, Smout A, El Taghdouini A, Blaya D, Rodrigo-Torres D, Graupera I, Aguilar-Bravo B, Chesne C, Najimi M, Sokal E, Lozano JJ, van Grunsven LA, Verfaillie CM, Sancho-Bru P. Coll M, et al. Among authors: van grunsven la. Cell Stem Cell. 2018 Jul 5;23(1):101-113.e7. doi: 10.1016/j.stem.2018.05.027. Epub 2018 Jun 28. Cell Stem Cell. 2018. PMID: 30049452 Free article.
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells.
Vallverdú J, Martínez García de la Torre RA, Mannaerts I, Verhulst S, Smout A, Coll M, Ariño S, Rubio-Tomás T, Aguilar-Bravo B, Martínez-Sánchez C, Blaya D, Verfaillie CM, van Grunsven LA, Sancho-Bru P. Vallverdú J, et al. Nat Protoc. 2021 May;16(5):2542-2563. doi: 10.1038/s41596-021-00509-1. Epub 2021 Apr 16. Nat Protoc. 2021. PMID: 33864055
A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model.
Kumar M, Toprakhisar B, Van Haele M, Antoranz A, Boon R, Chesnais F, De Smedt J, Tricot T, Idoype TI, Canella M, Tilliole P, De Boeck J, Bajaj M, Ranga A, Bosisio FM, Roskams T, van Grunsven LA, Verfaillie CM. Kumar M, et al. Biomaterials. 2021 Sep;276:121006. doi: 10.1016/j.biomaterials.2021.121006. Epub 2021 Jul 9. Biomaterials. 2021. PMID: 34304139 Free article.
Spatially Self-Organized Three-Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development.
Chai YC, To SK, Simorgh S, Zaunz S, Zhu Y, Ahuja K, Lemaitre A, Ramezankhani R, van der Veer BK, Wierda K, Verhulst S, van Grunsven LA, Pasque V, Verfaillie C. Chai YC, et al. Among authors: van grunsven la. Adv Sci (Weinh). 2024 Feb;11(5):e2304421. doi: 10.1002/advs.202304421. Epub 2023 Nov 30. Adv Sci (Weinh). 2024. PMID: 38037510 Free PMC article.
Human iPSC-derived liver co-culture spheroids to model liver fibrosis.
Cools L, Kazemzadeh Dastjerd M, Smout A, Merens V, Yang Y, Reynaert H, Messaoudi N, De Smet V, Kumar M, Verhulst S, Verfaillie C, van Grunsven LA. Cools L, et al. Among authors: van grunsven la. Biofabrication. 2024 Jun 12. doi: 10.1088/1758-5090/ad5766. Online ahead of print. Biofabrication. 2024. PMID: 38865994
144 results