Yauch RL - Search Results

1

The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.

Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG Jr, Iliopoulos O. Ohh M, et al. Among authors: yauch rl. Mol Cell. 1998 Jun;1(7):959-68. doi: 10.1016/s1097-2765(00)80096-9. Mol Cell. 1998. PMID: 9651579 Free article.

2

Defining extracellular integrin alpha-chain sites that affect cell adhesion and adhesion strengthening without altering soluble ligand binding.

Pujades C, Alon R, Yauch RL, Masumoto A, Burkly LC, Chen C, Springer TA, Lobb RR, Hemler ME. Pujades C, et al. Among authors: yauch rl. Mol Biol Cell. 1997 Dec;8(12):2647-57. doi: 10.1091/mbc.8.12.2647. Mol Biol Cell. 1997. PMID: 9398682 Free PMC article.

3

Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration.

Yauch RL, Berditchevski F, Harler MB, Reichner J, Hemler ME. Yauch RL, et al. Mol Biol Cell. 1998 Oct;9(10):2751-65. doi: 10.1091/mbc.9.10.2751. Mol Biol Cell. 1998. PMID: 9763442 Free PMC article.

4

Direct extracellular contact between integrin alpha(3)beta(1) and TM4SF protein CD151.

Yauch RL, Kazarov AR, Desai B, Lee RT, Hemler ME. Yauch RL, et al. J Biol Chem. 2000 Mar 31;275(13):9230-8. doi: 10.1074/jbc.275.13.9230. J Biol Chem. 2000. PMID: 10734060 Free article.

5

Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma.

Sharpe HJ, Pau G, Dijkgraaf GJ, Basset-Seguin N, Modrusan Z, Januario T, Tsui V, Durham AB, Dlugosz AA, Haverty PM, Bourgon R, Tang JY, Sarin KY, Dirix L, Fisher DC, Rudin CM, Sofen H, Migden MR, Yauch RL, de Sauvage FJ. Sharpe HJ, et al. Among authors: yauch rl. Cancer Cell. 2015 Mar 9;27(3):327-41. doi: 10.1016/j.ccell.2015.02.001. Cancer Cell. 2015. PMID: 25759019 Free PMC article.

6

Mutational evidence for control of cell adhesion through integrin diffusion/clustering, independent of ligand binding.

Yauch RL, Felsenfeld DP, Kraeft SK, Chen LB, Sheetz MP, Hemler ME. Yauch RL, et al. J Exp Med. 1997 Oct 20;186(8):1347-55. doi: 10.1084/jem.186.8.1347. J Exp Med. 1997. PMID: 9334374 Free PMC article.

7

Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinase.

Yauch RL, Hemler ME. Yauch RL, et al. Biochem J. 2000 Nov 1;351 Pt 3(Pt 3):629-37. Biochem J. 2000. PMID: 11042117 Free PMC article.

8

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

Yauch RL, Dijkgraaf GJ, Alicke B, Januario T, Ahn CP, Holcomb T, Pujara K, Stinson J, Callahan CA, Tang T, Bazan JF, Kan Z, Seshagiri S, Hann CL, Gould SE, Low JA, Rudin CM, de Sauvage FJ. Yauch RL, et al. Science. 2009 Oct 23;326(5952):572-4. doi: 10.1126/science.1179386. Epub 2009 Sep 2. Science. 2009. PMID: 19726788 Free PMC article.

9

Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance.

Dijkgraaf GJ, Alicke B, Weinmann L, Januario T, West K, Modrusan Z, Burdick D, Goldsmith R, Robarge K, Sutherlin D, Scales SJ, Gould SE, Yauch RL, de Sauvage FJ. Dijkgraaf GJ, et al. Among authors: yauch rl. Cancer Res. 2011 Jan 15;71(2):435-44. doi: 10.1158/0008-5472.CAN-10-2876. Epub 2010 Dec 1. Cancer Res. 2011. PMID: 21123452

10

Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened.

Tang T, Tang JY, Li D, Reich M, Callahan CA, Fu L, Yauch RL, Wang F, Kotkow K, Chang KS, Shpall E, Wu A, Rubin LL, Marsters JC Jr, Epstein EH Jr, Caro I, de Sauvage FJ. Tang T, et al. Among authors: yauch rl. Clin Cancer Res. 2011 May 15;17(10):3378-87. doi: 10.1158/1078-0432.CCR-10-3370. Epub 2011 May 10. Clin Cancer Res. 2011. PMID: 21558397 Free PMC article. Clinical Trial.

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