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Page 1
Whole-genome sequencing reveals host factors underlying critical COVID-19.
Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams CA, Walker S, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Rhodes D, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady-Crowe F, Todd L, Salehi S, Knight J, Elgar G, Chan G, Arumugam P, Patch C, Rendon A, Bentley D, Kingsley C, Kosmicki JA, Horowitz JE, Baras A, Abecasis GR, Ferreira MAR, Justice A, Mirshahi T, Oetjens M, Rader DJ, Ritchie MD, Verma A, Fowler TA, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Elliott P, Walsh T, Tenesa A; GenOMICC investigators; 23andMe investigators; COVID-19 Human Genetics Initiative; Fawkes A, Murphy L, Rowan K, Ponting CP, Vitart V, Wilson JF, Yang J, Bretherick AD, Scott RH, Hendry SC, Moutsianas L, Law A, Caulfield MJ, Baillie JK. Kousathanas A, et al. Nature. 2022 Jul;607(7917):97-103. doi: 10.1038/s41586-022-04576-6. Epub 2022 Mar 7. Nature. 2022. PMID: 35255492 Free PMC article.
Host genetic variation influences the development of illness requiring critical care(1) or hospitalization(2-4) after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are criticall …
Host genetic variation influences the development of illness requiring critical care(1) or hospitalization(2-4) after infection with SARS-Co …
Genetic mechanisms of critical illness in COVID-19.
Pairo-Castineira E, Clohisey S, Klaric L, Bretherick AD, Rawlik K, Pasko D, Walker S, Parkinson N, Fourman MH, Russell CD, Furniss J, Richmond A, Gountouna E, Wrobel N, Harrison D, Wang B, Wu Y, Meynert A, Griffiths F, Oosthuyzen W, Kousathanas A, Moutsianas L, Yang Z, Zhai R, Zheng C, Grimes G, Beale R, Millar J, Shih B, Keating S, Zechner M, Haley C, Porteous DJ, Hayward C, Yang J, Knight J, Summers C, Shankar-Hari M, Klenerman P, Turtle L, Ho A, Moore SC, Hinds C, Horby P, Nichol A, Maslove D, Ling L, McAuley D, Montgomery H, Walsh T, Pereira AC, Renieri A; GenOMICC Investigators; ISARIC4C Investigators; COVID-19 Human Genetics Initiative; 23andMe Investigators; BRACOVID Investigators; Gen-COVID Investigators; Shen X, Ponting CP, Fawkes A, Tenesa A, Caulfield M, Scott R, Rowan K, Murphy L, Openshaw PJM, Semple MG, Law A, Vitart V, Wilson JF, Baillie JK. Pairo-Castineira E, et al. Nature. 2021 Mar;591(7848):92-98. doi: 10.1038/s41586-020-03065-y. Epub 2020 Dec 11. Nature. 2021. PMID: 33307546
Host-mediated lung inflammation is present(1), and drives mortality(2), in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development(3). Here we re …
Host-mediated lung inflammation is present(1), and drives mortality(2), in the critical illness caused by coronavirus disease 2019 (C …
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, Naba A, Nakayasu ES, Qian WJ, Radtke A, Robson P, Stockwell BR, Van de Plas R, Vlachos IS, Zhou M; HuBMAP Consortium; Börner K, Snyder MP. Jain S, et al. Nat Cell Biol. 2023 Aug;25(8):1089-1100. doi: 10.1038/s41556-023-01194-w. Epub 2023 Jul 19. Nat Cell Biol. 2023. PMID: 37468756 Free PMC article. Review.
Cardiac rehabilitation in heart failure with severely reduced ejection fraction: effects on mortality.
Hosseini Mohammadi NS, Shaki Katouli MH, Masoudkabir F, Meysamie A, Tavakoli K, Vasheghani-Farahani A. Hosseini Mohammadi NS, et al. Heart Fail Rev. 2023 Jan;28(1):1-19. doi: 10.1007/s10741-022-10242-w. Epub 2022 May 21. Heart Fail Rev. 2023. PMID: 35596876 Review.
We were particularly interested in effect of cardiac rehabilitation on exercise capacity, quality of life, vascular effects, neuro-hormonal changes, and mortality. We also conducted a mini-systematic review and meta-analysis on randomized controlled trials comparing exerci …
We were particularly interested in effect of cardiac rehabilitation on exercise capacity, quality of life, vascular effects, neuro-hormonal …
Clinical echinococcosis.
Amir-Jahed AK, Fardin R, Farzad A, Bakshandeh K. Amir-Jahed AK, et al. Ann Surg. 1975 Nov;182(5):541-6. doi: 10.1097/00000658-197511000-00001. Ann Surg. 1975. PMID: 1190858 Free PMC article.
Except for 10 silent and 15 symptomatic cysts treated medically, all the rest were treated surgically by removal of the endocyst or resection of both endo and exocysts including 205 first, 31 second and 5 third procedures (1.75% of all major operations). Complications occurred in …
Except for 10 silent and 15 symptomatic cysts treated medically, all the rest were treated surgically by removal of the endocyst or resectio …
Effect of Different Blood Groups on Long-Term Outcomes of Surgical Revascularisation.
Yavari N, Masoudkabir F, Landy MG, Pashang M, Sadeghian S, Jalali A, Shafiee A, Roayaei P, Karimi A, Abbasi K, Forouzannia SK, Salehi Omran A, Bagheri J, Ahmadi Tafti SH. Yavari N, et al. Heart Lung Circ. 2022 Jun;31(6):873-881. doi: 10.1016/j.hlc.2021.11.003. Epub 2022 Jan 21. Heart Lung Circ. 2022. PMID: 35074263
The primary study endpoints were the occurrence of all-cause mortality and MACCE during long-term follow-ups. We used Cox regression survival analysis to define the association of ABO blood groups with the occurrence of MACCE. ...Our multivariable analysis demonstrated tha …
The primary study endpoints were the occurrence of all-cause mortality and MACCE during long-term follow-ups. We used Cox regression …
Diversity and genomics of giant viruses in the North Pacific Subtropical Gyre.
Farzad R, Ha AD, Aylward FO. Farzad R, et al. Front Microbiol. 2022 Nov 25;13:1021923. doi: 10.3389/fmicb.2022.1021923. eCollection 2022. Front Microbiol. 2022. PMID: 36504832 Free PMC article.
Large double-stranded DNA viruses of the phylum Nucleocytoviricota, often referred to as "giant viruses," are ubiquitous members of marine ecosystems that are important agents of mortality for eukaryotic plankton. Although giant viruses are known to be prevalent in marine …
Large double-stranded DNA viruses of the phylum Nucleocytoviricota, often referred to as "giant viruses," are ubiquitous members of marine e …
Fluoroquinolones-resistant Shigella species in Iranian children: a meta-analysis.
Khademi F, Sahebkar A. Khademi F, et al. World J Pediatr. 2019 Oct;15(5):441-453. doi: 10.1007/s12519-019-00263-1. Epub 2019 Jun 1. World J Pediatr. 2019. PMID: 31154582
BACKGROUND: Shigella is one of the most common causes of childhood dysentery along with high rate of morbidity and mortality in both developing and developed countries. According to the World Health Organization (WHO) reports, the prevalence of fluoroquinolones-resistant S …
BACKGROUND: Shigella is one of the most common causes of childhood dysentery along with high rate of morbidity and mortality in both …
Spontaneous coronary artery dissection and acute myocardial infarction in women.
Farzad A, Giesing W, Norvell C, Garrett JS, Velasco C. Farzad A, et al. Proc (Bayl Univ Med Cent). 2022 Jul 13;35(6):824-826. doi: 10.1080/08998280.2022.2094652. eCollection 2022. Proc (Bayl Univ Med Cent). 2022. PMID: 36304626 Free PMC article.
Further investigation is needed to clarify the ideal candidates for revascularization to optimize outcomes and limit morbidity and mortality....
Further investigation is needed to clarify the ideal candidates for revascularization to optimize outcomes and limit morbidity and mortal …
35 results