CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect.
Reil JC, Reil GH, Kovács Á, Sequeira V, Waddingham MT, Lodi M, Herwig M, Ghaderi S, Kreusser MM, Papp Z, Voigt N, Dobrev D, Meyhöfer S, Langer HF, Maier LS, Linz D, Mügge A, Hohl M, Steendijk P, Hamdani N.
Reil JC, et al.
J Physiol. 2020 Aug;598(15):3129-3153. doi: 10.1113/JP279607. Epub 2020 Jun 14.
J Physiol. 2020.
PMID: 32394454
Free PMC article.
LV pressure-volume (PV) analyses of isolated, preload controlled working hearts were performed at two afterload levels (60 and 100 mmHg) in C57BL/6N wild-type (WT) and CaMKII-double knockout mice (DKO(CaMKII) ). In snap-frozen WT hearts, force-pCa relationship, H(2) O(2) g …
LV pressure-volume (PV) analyses of isolated, preload controlled working hearts were performed at two afterload levels (60 and 100 mmHg) in …