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1985 2
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Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinical Trial.
INSPIRATION Investigators; Sadeghipour P, Talasaz AH, Rashidi F, Sharif-Kashani B, Beigmohammadi MT, Farrokhpour M, Sezavar SH, Payandemehr P, Dabbagh A, Moghadam KG, Jamalkhani S, Khalili H, Yadollahzadeh M, Riahi T, Rezaeifar P, Tahamtan O, Matin S, Abedini A, Lookzadeh S, Rahmani H, Zoghi E, Mohammadi K, Sadeghipour P, Abri H, Tabrizi S, Mousavian SM, Shahmirzaei S, Bakhshandeh H, Amin A, Rafiee F, Baghizadeh E, Mohebbi B, Parhizgar SE, Aliannejad R, Eslami V, Kashefizadeh A, Kakavand H, Hosseini SH, Shafaghi S, Ghazi SF, Najafi A, Jimenez D, Gupta A, Madhavan MV, Sethi SS, Parikh SA, Monreal M, Hadavand N, Hajighasemi A, Maleki M, Sadeghian S, Piazza G, Kirtane AJ, Van Tassell BW, Dobesh PP, Stone GW, Lip GYH, Krumholz HM, Goldhaber SZ, Bikdeli B. INSPIRATION Investigators, et al. JAMA. 2021 Apr 27;325(16):1620-1630. doi: 10.1001/jama.2021.4152. JAMA. 2021. PMID: 33734299 Free PMC article. Clinical Trial.
Prespecified safety outcomes included major bleeding according to the Bleeding Academic Research Consortium (type 3 or 5 definition), powered for noninferiority (a noninferiority margin of 1.8 based on odds ratio), and severe thrombocytopenia (platelet count <20 103/L). …
Prespecified safety outcomes included major bleeding according to the Bleeding Academic Research Consortium (type 3 or 5 definition), powere …
A global treatments for coronaviruses including COVID-19.
Yousefi B, Valizadeh S, Ghaffari H, Vahedi A, Karbalaei M, Eslami M. Yousefi B, et al. J Cell Physiol. 2020 Dec;235(12):9133-9142. doi: 10.1002/jcp.29785. Epub 2020 May 11. J Cell Physiol. 2020. PMID: 32394467 Free PMC article. Review.
In this article, we have tried to reach a therapeutic window of drugs available to patients with COVID-19. Cathepsin L is required for entry of the 2019-nCoV virus into the cell as target teicoplanin inhibits virus replication. ...
In this article, we have tried to reach a therapeutic window of drugs available to patients with COVID-19. Cathepsin L is required fo …
Expression of Lanthipeptides in Human Cells.
Eslami SM, Rahman IR, van der Donk WA. Eslami SM, et al. bioRxiv [Preprint]. 2023 Oct 23:2023.10.19.563208. doi: 10.1101/2023.10.19.563208. bioRxiv. 2023. PMID: 37961259 Free PMC article. Preprint.
In opposition to their linear counterparts, cyclic peptides, such as certain ribosomally synthesized and post-translationally modified peptides (RiPPs), are more conformationally constrained and less susceptible to proteolytic degradation. The lanthipeptide RiPP cytolysin L …
In opposition to their linear counterparts, cyclic peptides, such as certain ribosomally synthesized and post-translationally modified pepti …
Worldwide Survey of COVID-19-Associated Arrhythmias.
Coromilas EJ, Kochav S, Goldenthal I, Biviano A, Garan H, Goldbarg S, Kim JH, Yeo I, Tracy C, Ayanian S, Akar J, Singh A, Jain S, Zimerman L, Pimentel M, Osswald S, Twerenbold R, Schaerli N, Crotti L, Fabbri D, Parati G, Li Y, Atienza F, Zatarain E, Tse G, Leung KSK, Guevara-Valdivia ME, Rivera-Santiago CA, Soejima K, De Filippo P, Ferrari P, Malanchini G, Kanagaratnam P, Khawaja S, Mikhail GW, Scanavacca M, Abrahão Hajjar L, Rizerio B, Sacilotto L, Mollazadeh R, Eslami M, Laleh Far V, Mattioli AV, Boriani G, Migliore F, Cipriani A, Donato F, Compagnucci P, Casella M, Dello Russo A, Coromilas J, Aboyme A, O'Brien CG, Rodriguez F, Wang PJ, Naniwadekar A, Moey M, Kow CS, Cheah WK, Auricchio A, Conte G, Hwang J, Han S, Lazzerini PE, Franchi F, Santoro A, Capecchi PL, Joglar JA, Rosenblatt AG, Zardini M, Bricoli S, Bonura R, Echarte-Morales J, Benito-González T, Minguito-Carazo C, Fernández-Vázquez F, Wan EY. Coromilas EJ, et al. Circ Arrhythm Electrophysiol. 2021 Mar;14(3):e009458. doi: 10.1161/CIRCEP.120.009458. Epub 2021 Feb 7. Circ Arrhythm Electrophysiol. 2021. PMID: 33554620 Free PMC article.
Importance of gut microbiota metabolites in the development of cardiovascular diseases (CVD).
Hemmati M, Kashanipoor S, Mazaheri P, Alibabaei F, Babaeizad A, Asli S, Mohammadi S, Gorgin AH, Ghods K, Yousefi B, Eslami M. Hemmati M, et al. Life Sci. 2023 Sep 15;329:121947. doi: 10.1016/j.lfs.2023.121947. Epub 2023 Jul 16. Life Sci. 2023. PMID: 37463653 Review.
TMAO and SCFAs, human gut microbiota compounds, have respective immunomodulatory and pro-inflammatory effects. Choline and l-carnitine are abundant in high-fat diets and are transformed into TMA by gut bacteria. ...
TMAO and SCFAs, human gut microbiota compounds, have respective immunomodulatory and pro-inflammatory effects. Choline and l-carnitin …
Recent advancements in the production of rhamnolipid biosurfactants by Pseudomonas aeruginosa.
Eslami P, Hajfarajollah H, Bazsefidpar S. Eslami P, et al. RSC Adv. 2020 Sep 14;10(56):34014-34032. doi: 10.1039/d0ra04953k. eCollection 2020 Sep 10. RSC Adv. 2020. PMID: 35519061 Free PMC article. Review.
Reports show that RL productivity by the best-known producer, Pseudomonas aeruginosa, is very diverse, from less than 1 gr/l to more than 200 g L(-1). There are some major parameters that can affect RL productivity. ...
Reports show that RL productivity by the best-known producer, Pseudomonas aeruginosa, is very diverse, from less than 1 gr/l to more …
Aurothiomalate-Based Drugs as Potentially Novel Agents Against Leishmania major: A Mini Review.
Davoodi A, Eslami S, Fakhar M, Aazadbakht M, Montazeri M, Khoshvishkaie E, Keighobadi M. Davoodi A, et al. Acta Parasitol. 2022 Jun;67(2):640-647. doi: 10.1007/s11686-022-00536-2. Epub 2022 Apr 5. Acta Parasitol. 2022. PMID: 35380401 Review.
METHODS: In this study, we reviewed the proposed mechanisms of action of aurothiomalate and related compounds on the metabolism of L. major and collected data by searching relevant articles. RESULTS: Aurothiomalate-based drugs could be effective against leishmaniasis throu …
METHODS: In this study, we reviewed the proposed mechanisms of action of aurothiomalate and related compounds on the metabolism of L. …
Expression of BDNF-Associated lncRNAs in Parkinson's disease.
Akbari M, Gholipour M, Hussen BM, Taheri M, Eslami S, Sayad A, Ghafouri-Fard S. Akbari M, et al. Metab Brain Dis. 2022 Apr;37(4):901-909. doi: 10.1007/s11011-022-00946-1. Epub 2022 Mar 19. Metab Brain Dis. 2022. PMID: 35305235
There was no significant difference in expression of either gene between male and female PD patients or patients receiving L-Dopa versus those receiving other drugs. Expression of none of genes was correlated with age, disease duration, disease stage, MMSE or UPDRS. ...
There was no significant difference in expression of either gene between male and female PD patients or patients receiving L-Dopa ver …
168 results