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107 results

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Page 1
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma.
Steen CB, Luca BA, Esfahani MS, Azizi A, Sworder BJ, Nabet BY, Kurtz DM, Liu CL, Khameneh F, Advani RH, Natkunam Y, Myklebust JH, Diehn M, Gentles AJ, Newman AM, Alizadeh AA. Steen CB, et al. Cancer Cell. 2021 Oct 11;39(10):1422-1437.e10. doi: 10.1016/j.ccell.2021.08.011. Epub 2021 Sep 30. Cancer Cell. 2021. PMID: 34597589 Free PMC article.
An ultrasensitive method for detection of cell-free RNA.
Nesselbush MC, Luca BA, Jeon YJ, Jabara I, Meador CB, Garofalo A, Binkley MS, Hui AB, van 't Erve I, Xu N, Shi WY, Liu KJ, Sugio T, Kastelowitz N, Hamilton EG, Liu CL, Olsen M, Bonilla RF, Wang YP, Jiang A, Lau B, Eichholz J, Banwait M, Schroers-Martin J, Boegeholz J, King DA, Luikart H, Esfahani MS, Mehrmohamadi M, Stehr H, Raclin T, Tibshirani R, Khush K, Srinivas S, Yu H, Rogers AJ, Nair VS, Isbell JM, Li BT, Piotrowska Z, Sequist LV, Hata AN, Neal JW, Wakelee HA, Gentles AJ, Alizadeh AA, Diehn M. Nesselbush MC, et al. Nature. 2025 May;641(8063):759-768. doi: 10.1038/s41586-025-08834-1. Epub 2025 Apr 16. Nature. 2025. PMID: 40240612 Free PMC article.
Inferring gene expression from cell-free DNA fragmentation profiles.
Esfahani MS, Hamilton EG, Mehrmohamadi M, Nabet BY, Alig SK, King DA, Steen CB, Macaulay CW, Schultz A, Nesselbush MC, Soo J, Schroers-Martin JG, Chen B, Binkley MS, Stehr H, Chabon JJ, Sworder BJ, Hui AB, Frank MJ, Moding EJ, Liu CL, Newman AM, Isbell JM, Rudin CM, Li BT, Kurtz DM, Diehn M, Alizadeh AA. Esfahani MS, et al. Nat Biotechnol. 2022 Apr;40(4):585-597. doi: 10.1038/s41587-022-01222-4. Epub 2022 Mar 31. Nat Biotechnol. 2022. PMID: 35361996 Free PMC article.
Field-effect-informed urine liquid biopsy for bladder cancer.
Shi WY, Liu KJ, Esfahani MS, Mach KE, Phillips NA, Almanza D, Bajpai RK, Schroers-Martin JG, Trabanino L, Lee TJ, La V, Rodriguez G, Holton G, Chen SB, Mullane P, Wu DJ, Nesselbush MC, Sugio T, Cheng JC, Jabara I, Hamilton EG, Alig SK, Liu CL, Peterson DJ, Prado K, Shkolyar E, Thong A, Shah JB, Gill H, Kunder CA, Chan E, Khaki AR, Skinner EC, Alizadeh AA, Liao JC, Diehn M. Shi WY, et al. Cell. 2026 Feb 19;189(4):1024-1038.e9. doi: 10.1016/j.cell.2025.12.054. Epub 2026 Jan 27. Cell. 2026. PMID: 41605210 Free PMC article.
Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA.
Scherer F, Kurtz DM, Newman AM, Stehr H, Craig AF, Esfahani MS, Lovejoy AF, Chabon JJ, Klass DM, Liu CL, Zhou L, Glover C, Visser BC, Poultsides GA, Advani RH, Maeda LS, Gupta NK, Levy R, Ohgami RS, Kunder CA, Diehn M, Alizadeh AA. Scherer F, et al. Sci Transl Med. 2016 Nov 9;8(364):364ra155. doi: 10.1126/scitranslmed.aai8545. Sci Transl Med. 2016. PMID: 27831904 Free PMC article.
Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition.
Nabet BY, Esfahani MS, Moding EJ, Hamilton EG, Chabon JJ, Rizvi H, Steen CB, Chaudhuri AA, Liu CL, Hui AB, Almanza D, Stehr H, Gojenola L, Bonilla RF, Jin MC, Jeon YJ, Tseng D, Liu C, Merghoub T, Neal JW, Wakelee HA, Padda SK, Ramchandran KJ, Das M, Plodkowski AJ, Yoo C, Chen EL, Ko RB, Newman AM, Hellmann MD, Alizadeh AA, Diehn M. Nabet BY, et al. Cell. 2020 Oct 15;183(2):363-376.e13. doi: 10.1016/j.cell.2020.09.001. Epub 2020 Oct 1. Cell. 2020. PMID: 33007267 Free PMC article.
INTERLINK-1: A Phase III, Randomized, Placebo-Controlled Study of Monalizumab plus Cetuximab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma.
Fayette J, Licitra L, Harrington K, Haddad R, Siu LL, Liu YC, Tahara M, Machiels JP, Rischin D, Seiwert TY, Ferris RL, Keilholz U, Psyrri A, Keam B, Bossi P, Metcalf R, Hsieh CY, Clement PMJ, Isaev P, Mudunov A, Dinis J, Hoeben A, Kasper S, Klinghammer K, Hwang M, Blando J, Serrano O, Ruscica D, Cohen RB; INTERLINK-1 investigators. Fayette J, et al. Clin Cancer Res. 2025 Jul 1;31(13):2617-2627. doi: 10.1158/1078-0432.CCR-25-0073. Clin Cancer Res. 2025. PMID: 40300079 Free PMC article. Clinical Trial.
PURPOSE: Treatment options for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) after failure of immune checkpoint inhibitor treatment and platinum-based chemotherapy are limited. Preliminary data suggested that monalizumab plus cetuximab had clinic …
PURPOSE: Treatment options for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) after failure of immune check …
Development of a fibrin-targeted theranostic for gastric cancer.
Esfahani SA, Ma L, Krishna S, Ma H, Raheem SJ, Shuvaev S, Rotile NJ, Weigand-Whittier J, Boice AT, Borges N, Treaba CA, Deffler C, Diyabalanage H, Humblet V, Sosnovik DE, Mahmood U, Heidari P, Shih A, Catana C, Strickland MR, Klempner SJ, Caravan P. Esfahani SA, et al. Sci Transl Med. 2024 Dec 11;16(777):eadn7218. doi: 10.1126/scitranslmed.adn7218. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661705 Free PMC article.
CAR19 therapy drives expansion of clonal hematopoiesis and associated cytopenias.
Hamilton MP, Phillips N, Noordenbos T, Boegeholz J, Sugio T, Sworder BJ, Alig SK, Good Z, Schroers-Martin JG, Tamaresis J, Esfahani MS, Lu Y, Olsen M, Liu CL, Ehlinger Z, Desai M, Muffly L, Negrin RS, Arai S, Johnston L, Lowsky R, Meyer E, Rezvani A, Shizuru J, Weng WK, Shiraz P, Sidana S, Bharadwaj S, Smith M, Dahiya S, Sahaf B, Frank MJ, Mackall CL, Diehn M, Kurtz DM, Miklos DB, Alizadeh AA. Hamilton MP, et al. Res Sq [Preprint]. 2025 Oct 21:rs.3.rs-7746241. doi: 10.21203/rs.3.rs-7746241/v1. Res Sq. 2025. PMID: 41282159 Free PMC article. Preprint.
107 results