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Trial of Prasinezumab in Early-Stage Parkinson's Disease.
Pagano G, Taylor KI, Anzures-Cabrera J, Marchesi M, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Azulay JP, Mollenhauer B, López-Manzanares L, Russell DS, Boyd JT, Nicholas AP, Luquin MR, Hauser RA, Gasser T, Poewe W, Ricci B, Boulay A, Vogt A, Boess FG, Dukart J, D'Urso G, Finch R, Zanigni S, Monnet A, Pross N, Hahn A, Svoboda H, Britschgi M, Lipsmeier F, Volkova-Volkmar E, Lindemann M, Dziadek S, Holiga Š, Rukina D, Kustermann T, Kerchner GA, Fontoura P, Umbricht D, Doody R, Nikolcheva T, Bonni A; PASADENA Investigators; Prasinezumab Study Group. Pagano G, et al. N Engl J Med. 2022 Aug 4;387(5):421-432. doi: 10.1056/NEJMoa2202867. N Engl J Med. 2022. PMID: 35921451 Clinical Trial.
Circulating miR-26b-5p and miR-451a as diagnostic biomarkers in medullary thyroid carcinoma patients.
Besharat ZM, Trocchianesi S, Verrienti A, Ciampi R, Cantara S, Romei C, Sabato C, Noviello TMR, Po A, Citarella A, Caruso FP, Panariello I, Gianno F, Carpino G, Gaudio E, Chiacchiarini M, Masuelli L, Sponziello M, Pecce V, Ramone T, Maino F, Dotta F, Ceccarelli M, Pezzullo L, Durante C, Castagna MG, Elisei R, Ferretti E. Besharat ZM, et al. J Endocrinol Invest. 2023 Dec;46(12):2583-2599. doi: 10.1007/s40618-023-02115-2. Epub 2023 Jun 7. J Endocrinol Invest. 2023. PMID: 37286863 Free PMC article.
The endocrine disruptor cadmium modulates the androgen-estrogen receptors ratio and induces inflammatory cytokines in luminal (A) cell models of breast cancer.
Bimonte VM, Catanzaro G, Po A, Trocchianesi S, Besharat ZM, Spinello Z, Curreli M, Fabi A, Bei R, Milella M, Vacca A, Ferretti E, Migliaccio S. Bimonte VM, et al. Endocrine. 2024 Mar;83(3):798-809. doi: 10.1007/s12020-023-03594-2. Epub 2023 Nov 18. Endocrine. 2024. PMID: 37979099 Free PMC article.
Thus, aim of this study was to evaluate effects of Cd on Luminal A BC estrogen receptor (ER) positive/progesterone receptor positive cell models in vitro to characterize the mechanism(s) involved in breast cell homeostasis disruption. METHODS: T47D and MCF7 were exposed to Cd (0. …
Thus, aim of this study was to evaluate effects of Cd on Luminal A BC estrogen receptor (ER) positive/progesterone receptor positive cell mo …
Electric field induced alignment of graphene oxide nanoplatelets in polyethersulfone matrix.
Besharat F, Manteghian M, Gallone G, Lazzeri A. Besharat F, et al. Nanotechnology. 2020 Apr 10;31(15):155701. doi: 10.1088/1361-6528/ab646b. Epub 2019 Dec 20. Nanotechnology. 2020. PMID: 31860895
Aligned GO/PES nanocomposite membrane films were prepared by non-solvent phase inversion technique after the starting sol phase was preliminarily exposed to high electric fields (50 kV m(-1)). Either AC (100, 1000 Hz) or DC mode electric fields were alternatively employed, …
Aligned GO/PES nanocomposite membrane films were prepared by non-solvent phase inversion technique after the starting sol phase was prelimin …
The impact of sleeve gastrectomy on polycystic ovarian syndrome: a single-center 1-year cohort study.
Alamdari NM, Sadegh GHM, Farsi Y, Besharat S, Hajimirzaie SH, Abbasi M. Alamdari NM, et al. Ir J Med Sci. 2024 Apr;193(2):721-724. doi: 10.1007/s11845-023-03488-2. Epub 2023 Aug 14. Ir J Med Sci. 2024. PMID: 37574528
METHODS: Female patients with a definite diagnosis of PCOS and body mass index (BMI) > 40 kg/m(2) who were candidates for sleeve gastrectomy were enrolled in this cohort study and followed for 1 year postoperatively. ...The mean BMI before and after the surgery was 44.2 …
METHODS: Female patients with a definite diagnosis of PCOS and body mass index (BMI) > 40 kg/m(2) who were candidates for sleeve g …