N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis.
Hansen JM, Golchin SA, Veyrier FJ, Domenech P, Boneca IG, Azad AK, Rajaram MV, Schlesinger LS, Divangahi M, Reed MB, Behr MA.
Hansen JM, et al.
J Infect Dis. 2014 Apr 1;209(7):1045-54. doi: 10.1093/infdis/jit622. Epub 2013 Nov 21.
J Infect Dis. 2014.
PMID: 24265438
These results indicate that the modified MDP is an important contributor to the unusual immunogenicity of mycobacteria but has a limited role in the pathogenesis of M. tuberculosis infection....
These results indicate that the modified MDP is an important contributor to the unusual immunogenicity of mycobacteria but has a limited rol …