Anomalous K(v) 7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H(2) S and persulfidation in skeletal muscle.
Vellecco V, Martelli A, Bibli IS, Vallifuoco M, Manzo OL, Panza E, Citi V, Calderone V, de Dominicis G, Cozzolino C, Basso EM, Mariniello M, Fleming I, Mancini A, Bucci M, Cirino G.
Vellecco V, et al.
Br J Pharmacol. 2020 Feb;177(4):810-823. doi: 10.1111/bph.14700. Epub 2019 May 3.
Br J Pharmacol. 2020.
PMID: 31051045
Free PMC article.
This increase contributes to skeletal muscle hypercontractility. K(v) 7 channels, expressed in skeletal muscle, may be a molecular target for H(2) S. ...Development and characterization of primary human skeletal muscle cells (PHSKMC) and evaluation of cell membrane potenti …
This increase contributes to skeletal muscle hypercontractility. K(v) 7 channels, expressed in skeletal muscle, may be a molecular ta …