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Year | Number of Results |
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2002 | 2 |
2003 | 3 |
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Page 1
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.
J Med Chem. 2002 Aug 1;45(16):3381-93. doi: 10.1021/jm020056z.
J Med Chem. 2002.
PMID: 12139449
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor.
Davies TG, Bentley J, Arris CE, Boyle FT, Curtin NJ, Endicott JA, Gibson AE, Golding BT, Griffin RJ, Hardcastle IR, Jewsbury P, Johnson LN, Mesguiche V, Newell DR, Noble ME, Tucker JA, Wang L, Whitfield HJ.
Davies TG, et al. Among authors: mesguiche v.
Nat Struct Biol. 2002 Oct;9(10):745-9. doi: 10.1038/nsb842.
Nat Struct Biol. 2002.
PMID: 12244298
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N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2.
Hardcastle IR, Arris CE, Bentley J, Boyle FT, Chen Y, Curtin NJ, Endicott JA, Gibson AE, Golding BT, Griffin RJ, Jewsbury P, Menyerol J, Mesguiche V, Newell DR, Noble ME, Pratt DJ, Wang LZ, Whitfield HJ.
Hardcastle IR, et al. Among authors: mesguiche v.
J Med Chem. 2004 Jul 15;47(15):3710-22. doi: 10.1021/jm0311442.
J Med Chem. 2004.
PMID: 15239650
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Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2.
Sayle KL, Bentley J, Boyle FT, Calvert AH, Cheng Y, Curtin NJ, Endicott JA, Golding BT, Hardcastle IR, Jewsbury P, Mesguiche V, Newell DR, Noble ME, Parsons RJ, Pratt DJ, Wang LZ, Griffin RJ.
Sayle KL, et al. Among authors: mesguiche v.
Bioorg Med Chem Lett. 2003 Sep 15;13(18):3079-82. doi: 10.1016/s0960-894x(03)00651-6.
Bioorg Med Chem Lett. 2003.
PMID: 12941338
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4-Alkoxy-2,6-diaminopyrimidine derivatives: inhibitors of cyclin dependent kinases 1 and 2.
Mesguiche V, Parsons RJ, Arris CE, Bentley J, Boyle FT, Curtin NJ, Davies TG, Endicott JA, Gibson AE, Golding BT, Griffin RJ, Jewsbury P, Johnson LN, Newell DR, Noble ME, Wang LZ, Hardcastle IR.
Mesguiche V, et al.
Bioorg Med Chem Lett. 2003 Jan 20;13(2):217-22. doi: 10.1016/s0960-894x(02)00884-3.
Bioorg Med Chem Lett. 2003.
PMID: 12482427
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Facilitation of addition-elimination reactions in pyrimidines and purines using trifluoroacetic acid in trifluoroethanol.
Whitfield HJ, Griffin RJ, Hardcastle IR, Henderson A, Meneyrol J, Mesguiche V, Sayle KL, Golding BT.
Whitfield HJ, et al. Among authors: mesguiche v.
Chem Commun (Camb). 2003 Nov 21;(22):2802-3. doi: 10.1039/b308948g.
Chem Commun (Camb). 2003.
PMID: 14651112
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Structure-based design of 2-arylamino-4-cyclohexylmethoxy-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinase 2.
Marchetti F, Sayle KL, Bentley J, Clegg W, Curtin NJ, Endicott JA, Golding BT, Griffin RJ, Haggerty K, Harrington RW, Mesguiche V, Newell DR, Noble ME, Parsons RJ, Pratt DJ, Wang LZ, Hardcastle IR.
Marchetti F, et al. Among authors: mesguiche v.
Org Biomol Chem. 2007 May 21;5(10):1577-85. doi: 10.1039/b703241b. Epub 2007 Apr 23.
Org Biomol Chem. 2007.
PMID: 17571187
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