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Page 1
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Müller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J. Machnik A, et al. Among authors: alitalo k. Nat Med. 2009 May;15(5):545-52. doi: 10.1038/nm.1960. Epub 2009 May 3. Nat Med. 2009. PMID: 19412173
Lymphangiogenic gene therapy with minimal blood vascular side effects.
Saaristo A, Veikkola T, Tammela T, Enholm B, Karkkainen MJ, Pajusola K, Bueler H, Ylä-Herttuala S, Alitalo K. Saaristo A, et al. Among authors: alitalo k. J Exp Med. 2002 Sep 16;196(6):719-30. doi: 10.1084/jem.20020587. J Exp Med. 2002. PMID: 12235206 Free PMC article.
Genesis and pathogenesis of lymphatic vessels.
Jeltsch M, Tammela T, Alitalo K, Wilting J. Jeltsch M, et al. Among authors: alitalo k. Cell Tissue Res. 2003 Oct;314(1):69-84. doi: 10.1007/s00441-003-0777-2. Epub 2003 Aug 27. Cell Tissue Res. 2003. PMID: 12942362 Review.
The biology of vascular endothelial growth factors.
Tammela T, Enholm B, Alitalo K, Paavonen K. Tammela T, et al. Among authors: alitalo k. Cardiovasc Res. 2005 Feb 15;65(3):550-63. doi: 10.1016/j.cardiores.2004.12.002. Cardiovasc Res. 2005. PMID: 15664381 Review.
Molecular lymphangiogenesis: new players.
Tammela T, Petrova TV, Alitalo K. Tammela T, et al. Among authors: alitalo k. Trends Cell Biol. 2005 Aug;15(8):434-41. doi: 10.1016/j.tcb.2005.06.004. Trends Cell Biol. 2005. PMID: 16005628 Review.
VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain.
Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Bréant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL. Le Bras B, et al. Among authors: alitalo k. Nat Neurosci. 2006 Mar;9(3):340-8. doi: 10.1038/nn1646. Epub 2006 Feb 5. Nat Neurosci. 2006. PMID: 16462734
Early lymph vessel development from embryonic stem cells.
Kreuger J, Nilsson I, Kerjaschki D, Petrova T, Alitalo K, Claesson-Welsh L. Kreuger J, et al. Among authors: alitalo k. Arterioscler Thromb Vasc Biol. 2006 May;26(5):1073-8. doi: 10.1161/01.ATV.0000217610.58032.b7. Epub 2006 Mar 16. Arterioscler Thromb Vasc Biol. 2006. PMID: 16543496
Vascular endothelial growth factor-C accelerates diabetic wound healing.
Saaristo A, Tammela T, Farkkilā A, Kärkkäinen M, Suominen E, Yla-Herttuala S, Alitalo K. Saaristo A, et al. Among authors: alitalo k. Am J Pathol. 2006 Sep;169(3):1080-7. doi: 10.2353/ajpath.2006.051251. Am J Pathol. 2006. PMID: 16936280 Free PMC article.
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.
Tammela T, Zarkada G, Wallgard E, Murtomäki A, Suchting S, Wirzenius M, Waltari M, Hellström M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Ylä-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K. Tammela T, et al. Among authors: alitalo k. Nature. 2008 Jul 31;454(7204):656-60. doi: 10.1038/nature07083. Epub 2008 Jun 25. Nature. 2008. PMID: 18594512
Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation.
Bry M, Kivelä R, Holopainen T, Anisimov A, Tammela T, Soronen J, Silvola J, Saraste A, Jeltsch M, Korpisalo P, Carmeliet P, Lemström KB, Shibuya M, Ylä-Herttuala S, Alhonen L, Mervaala E, Andersson LC, Knuuti J, Alitalo K. Bry M, et al. Among authors: alitalo k. Circulation. 2010 Oct 26;122(17):1725-33. doi: 10.1161/CIRCULATIONAHA.110.957332. Epub 2010 Oct 11. Circulation. 2010. PMID: 20937974
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization.
Tvorogov D, Anisimov A, Zheng W, Leppänen VM, Tammela T, Laurinavicius S, Holnthoner W, Heloterä H, Holopainen T, Jeltsch M, Kalkkinen N, Lankinen H, Ojala PM, Alitalo K. Tvorogov D, et al. Among authors: alitalo k. Cancer Cell. 2010 Dec 14;18(6):630-40. doi: 10.1016/j.ccr.2010.11.001. Epub 2010 Dec 2. Cancer Cell. 2010. PMID: 21130043 Free article.
Biological basis of therapeutic lymphangiogenesis.
Norrmén C, Tammela T, Petrova TV, Alitalo K. Norrmén C, et al. Among authors: alitalo k. Circulation. 2011 Mar 29;123(12):1335-51. doi: 10.1161/CIRCULATIONAHA.107.704098. Circulation. 2011. PMID: 21444892 Review. No abstract available.
Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis.
Calvo CF, Fontaine RH, Soueid J, Tammela T, Makinen T, Alfaro-Cervello C, Bonnaud F, Miguez A, Benhaim L, Xu Y, Barallobre MJ, Moutkine I, Lyytikkä J, Tatlisumak T, Pytowski B, Zalc B, Richardson W, Kessaris N, Garcia-Verdugo JM, Alitalo K, Eichmann A, Thomas JL. Calvo CF, et al. Among authors: alitalo k. Genes Dev. 2011 Apr 15;25(8):831-44. doi: 10.1101/gad.615311. Genes Dev. 2011. PMID: 21498572 Free PMC article.
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Tammela T, Zarkada G, Nurmi H, Jakobsson L, Heinolainen K, Tvorogov D, Zheng W, Franco CA, Murtomäki A, Aranda E, Miura N, Ylä-Herttuala S, Fruttiger M, Mäkinen T, Eichmann A, Pollard JW, Gerhardt H, Alitalo K. Tammela T, et al. Among authors: alitalo k. Nat Cell Biol. 2011 Sep 11;13(10):1202-13. doi: 10.1038/ncb2331. Nat Cell Biol. 2011. PMID: 21909098 Free PMC article.
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis.
Anisimov A, Tvorogov D, Alitalo A, Leppänen VM, An Y, Han EC, Orsenigo F, Gaál EI, Holopainen T, Koh YJ, Tammela T, Korpisalo P, Keskitalo S, Jeltsch M, Ylä-Herttuala S, Dejana E, Koh GY, Choi C, Saharinen P, Alitalo K. Anisimov A, et al. Among authors: alitalo a, alitalo k. Circulation. 2013 Jan 29;127(4):424-34. doi: 10.1161/CIRCULATIONAHA.112.127472. Circulation. 2013. PMID: 23357661
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.
Wiig H, Schröder A, Neuhofer W, Jantsch J, Kopp C, Karlsen TV, Boschmann M, Goss J, Bry M, Rakova N, Dahlmann A, Brenner S, Tenstad O, Nurmi H, Mervaala E, Wagner H, Beck FX, Müller DN, Kerjaschki D, Luft FC, Harrison DG, Alitalo K, Titze J. Wiig H, et al. Among authors: alitalo k. J Clin Invest. 2013 Jul;123(7):2803-15. doi: 10.1172/JCI60113. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722907 Free PMC article.
Growth factor therapy and lymph node graft for lymphedema.
Tervala TV, Hartiala P, Tammela T, Visuri MT, Ylä-Herttuala S, Alitalo K, Saarikko AM. Tervala TV, et al. Among authors: alitalo k. J Surg Res. 2015 Jun 1;196(1):200-7. doi: 10.1016/j.jss.2015.02.031. Epub 2015 Feb 19. J Surg Res. 2015. PMID: 25777822
VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling.
Heinolainen K, Karaman S, D'Amico G, Tammela T, Sormunen R, Eklund L, Alitalo K, Zarkada G. Heinolainen K, et al. Among authors: alitalo k. Circ Res. 2017 Apr 28;120(9):1414-1425. doi: 10.1161/CIRCRESAHA.116.310477. Epub 2017 Mar 15. Circ Res. 2017. PMID: 28298294 Free PMC article.
Vascular endothelial growth factors VEGF-B and VEGF-C.
Joukov V, Kaipainen A, Jeltsch M, Pajusola K, Olofsson B, Kumar V, Eriksson U, Alitalo K. Joukov V, et al. Among authors: alitalo k. J Cell Physiol. 1997 Nov;173(2):211-5. doi: 10.1002/(SICI)1097-4652(199711)173:2<211::AID-JCP23>3.0.CO;2-H. J Cell Physiol. 1997. PMID: 9365524 Review. No abstract available.
Vascular endothelial growth factor receptor-3.
Taipale J, Makinen T, Arighi E, Kukk E, Karkkainen M, Alitalo K. Taipale J, et al. Among authors: alitalo k. Curr Top Microbiol Immunol. 1999;237:85-96. doi: 10.1007/978-3-642-59953-8_5. Curr Top Microbiol Immunol. 1999. PMID: 9893347 Review. No abstract available.
Vascular growth factors and lymphangiogenesis.
Jussila L, Alitalo K. Jussila L, et al. Among authors: alitalo k. Physiol Rev. 2002 Jul;82(3):673-700. doi: 10.1152/physrev.00005.2002. Physiol Rev. 2002. PMID: 12087132 Free article. Review.
Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.
Tammela T, Saaristo A, Lohela M, Morisada T, Tornberg J, Norrmén C, Oike Y, Pajusola K, Thurston G, Suda T, Yla-Herttuala S, Alitalo K. Tammela T, et al. Among authors: alitalo k. Blood. 2005 Jun 15;105(12):4642-8. doi: 10.1182/blood-2004-08-3327. Epub 2005 Mar 3. Blood. 2005. PMID: 15746084 Free article.
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy.
Karpanen T, Bry M, Ollila HM, Seppänen-Laakso T, Liimatta E, Leskinen H, Kivelä R, Helkamaa T, Merentie M, Jeltsch M, Paavonen K, Andersson LC, Mervaala E, Hassinen IE, Ylä-Herttuala S, Oresic M, Alitalo K. Karpanen T, et al. Among authors: alitalo k. Circ Res. 2008 Oct 24;103(9):1018-26. doi: 10.1161/CIRCRESAHA.108.178459. Epub 2008 Aug 28. Circ Res. 2008. PMID: 18757827 Free PMC article.
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