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Page 1
Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial.
Heerspink HJL, Radhakrishnan J, Alpers CE, Barratt J, Bieler S, Diva U, Inrig J, Komers R, Mercer A, Noronha IL, Rheault MN, Rote W, Rovin B, Trachtman H, Trimarchi H, Wong MG, Perkovic V; PROTECT Investigators. Heerspink HJL, et al. Among authors: rovin b. Lancet. 2023 May 13;401(10388):1584-1594. doi: 10.1016/S0140-6736(23)00569-X. Epub 2023 Apr 1. Lancet. 2023. PMID: 37015244 Clinical Trial.
The authors reply.
Barratt J, Rovin BH; NefIgArd Investigators. Barratt J, et al. Kidney Int. 2023 May;103(5):994-995. doi: 10.1016/j.kint.2023.02.014. Kidney Int. 2023. PMID: 37085260 No abstract available.
The authors reply.
Barratt J, Rovin BH; NefIgArd Investigators. Barratt J, et al. Kidney Int. 2023 May;103(5):996. doi: 10.1016/j.kint.2023.02.015. Kidney Int. 2023. PMID: 37085263 No abstract available.
The authors reply.
Barratt J, Rovin BH; NefIgArd Investigators. Barratt J, et al. Kidney Int. 2023 May;103(5):997. doi: 10.1016/j.kint.2023.02.016. Kidney Int. 2023. PMID: 37085265 No abstract available.
Targeting the Alternative Complement Pathway With Iptacopan to Treat IgA Nephropathy: Design and Rationale of the APPLAUSE-IgAN Study.
Rizk DV, Rovin BH, Zhang H, Kashihara N, Maes B, Trimarchi H, Perkovic V, Meier M, Kollins D, Papachristofi O, Charney A, Barratt J. Rizk DV, et al. Among authors: rovin bh. Kidney Int Rep. 2023 Feb 9;8(5):968-979. doi: 10.1016/j.ekir.2023.01.041. eCollection 2023 May. Kidney Int Rep. 2023. PMID: 37180505 Free PMC article.
IgA Nephropathy Patient Baseline Characteristics in the Sparsentan PROTECT Study.
Barratt J, Rovin B, Wong MG, Alpers CE, Bieler S, He P, Inrig J, Komers R, Heerspink HJL, Mercer A, Noronha IL, Radhakrishnan J, Rheault MN, Rote W, Trachtman H, Trimarchi H, Perkovic V; PROTECT investigators. Barratt J, et al. Among authors: rovin b. Kidney Int Rep. 2023 Mar 4;8(5):1043-1056. doi: 10.1016/j.ekir.2023.02.1086. eCollection 2023 May. Kidney Int Rep. 2023. PMID: 37180506 Free PMC article.
Efficacy and safety of a targeted-release formulation of budesonide in patients with primary IgA nephropathy (NefIgArd): 2-year results from a randomised phase 3 trial.
Lafayette R, Kristensen J, Stone A, Floege J, Tesař V, Trimarchi H, Zhang H, Eren N, Paliege A, Reich HN, Rovin BH, Barratt J; NefIgArd trial investigators. Lafayette R, et al. Lancet. 2023 Sep 9;402(10405):859-870. doi: 10.1016/S0140-6736(23)01554-4. Epub 2023 Aug 14. Lancet. 2023. PMID: 37591292 Clinical Trial.
Results of a randomized double-blind placebo-controlled Phase 2 study propose iptacopan as an alternative complement pathway inhibitor for IgA nephropathy.
Zhang H, Rizk DV, Perkovic V, Maes B, Kashihara N, Rovin B, Trimarchi H, Sprangers B, Meier M, Kollins D, Papachristofi O, Milojevic J, Junge G, Nidamarthy PK, Charney A, Barratt J. Zhang H, et al. Among authors: rovin b. Kidney Int. 2024 Jan;105(1):189-199. doi: 10.1016/j.kint.2023.09.027. Epub 2023 Oct 31. Kidney Int. 2024. PMID: 37914086 Free article. Clinical Trial.
Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis.
Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae DW, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, Trachtman H; DUPRO Steering Committee and DUPLEX Investigators. Rheault MN, et al. Among authors: rovin b. N Engl J Med. 2023 Dec 28;389(26):2436-2445. doi: 10.1056/NEJMoa2308550. Epub 2023 Nov 3. N Engl J Med. 2023. PMID: 37921461 Clinical Trial.
Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial.
Rovin BH, Barratt J, Heerspink HJL, Alpers CE, Bieler S, Chae DW, Diva UA, Floege J, Gesualdo L, Inrig JK, Kohan DE, Komers R, Kooienga LA, Lafayette R, Maes B, Małecki R, Mercer A, Noronha IL, Oh SW, Peh CA, Praga M, Preciado P, Radhakrishnan J, Rheault MN, Rote WE, Tang SCW, Tesar V, Trachtman H, Trimarchi H, Tumlin JA, Wong MG, Perkovic V; DUPRO steering committee and PROTECT Investigators. Rovin BH, et al. Lancet. 2023 Dec 2;402(10417):2077-2090. doi: 10.1016/S0140-6736(23)02302-4. Epub 2023 Nov 3. Lancet. 2023. PMID: 37931634 Clinical Trial.
Randomized Trial on the Effect of an Oral Spleen Tyrosine Kinase Inhibitor in the Treatment of IgA Nephropathy.
Tam FWK, Tumlin J, Barratt J, Rovin BH, Roberts ISD, Roufosse C, Cook HT, Bhangal G, Brown AL, Busch M, Dudhiya F, Duliege AM, Fraser DJ, Gale DP, Huang CC, Lai PC, Lee M, Masuda ES, McAdoo SP, Rosenkranz AR, Sommerer C, Sunder-Plassmann G, Szeto CC, Tang SCW, Williamson DE, Willcocks L, Vielhauer V, Kim MJ, Todd L, Zayed H, Tong-Starksen S, Lafayette R. Tam FWK, et al. Kidney Int Rep. 2023 Sep 30;8(12):2546-2556. doi: 10.1016/j.ekir.2023.09.024. eCollection 2023 Dec. Kidney Int Rep. 2023. PMID: 38106605 Free PMC article.
Effect of Belimumab on Preventing de novo Renal Lupus Flares.
Parodis I, Lindblom J, Cetrez N, Palazzo L, Ala H, Houssiau FA, Sjöwall C, Rovin BH. Parodis I, et al. Kidney Int Rep. 2023 Jul 6;8(9):1822-1830. doi: 10.1016/j.ekir.2023.06.021. eCollection 2023 Sep. Kidney Int Rep. 2023. PMID: 37705915 Free PMC article.
Corrigendum to "KDIGO 2024 Clinical Practice Guideline for the Management of Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis." Kidney Int. 2024;105(3S):S71-S116.
Kidney Disease: Improving Global Outcomes (KDIGO) ANCA Vasculitis Work Group. Kidney Disease: Improving Global Outcomes (KDIGO) ANCA Vasculitis Work Group. Kidney Int. 2024 May 8:S0085-2538(24)00266-7. doi: 10.1016/j.kint.2024.04.003. Online ahead of print. Kidney Int. 2024. PMID: 38739061 No abstract available.
Corrigendum to "Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Management of ANCA-Associated Vasculitis." Kidney Int. 2024;105(3):447-449.
Floege J, Jayne DRW, Sanders JF, Tesar V, Balk EM, Gordon CE, Adam G, Tonelli MA, Cheung M, Earley A, Rovin BH. Floege J, et al. Among authors: rovin bh. Kidney Int. 2024 May 8:S0085-2538(24)00267-9. doi: 10.1016/j.kint.2024.04.004. Online ahead of print. Kidney Int. 2024. PMID: 38739060 No abstract available.
Green nephrology: an editor's journey.
De Chiara L, Ronco P, Rovin BH. De Chiara L, et al. Among authors: rovin bh. J Nephrol. 2024 Jan;37(1):3-5. doi: 10.1007/s40620-024-01890-2. J Nephrol. 2024. PMID: 38401016 No abstract available.
Mycophenolate mofetil withdrawal in patients with systemic lupus erythematosus: a multicentre, open-label, randomised controlled trial.
Chakravarty EF, Utset T, Kamen DL, Contreras G, McCune WJ, Aranow C, Kalunian K, Massarotti E, Clowse MEB, Rovin BH, Lim SS, Majithia V, Dall'Era M, Looney RJ, Erkan D, Saxena A, Olsen NJ, Ko K, Guthridge JM, Goldmuntz E, Springer J, D'Aveta C, Keyes-Elstein L, Barry B, Pinckney A, McNamara J, James JA. Chakravarty EF, et al. Among authors: rovin bh. Lancet Rheumatol. 2024 Mar;6(3):e168-e177. doi: 10.1016/S2665-9913(23)00320-X. Epub 2024 Jan 29. Lancet Rheumatol. 2024. PMID: 38301682 Clinical Trial.
The chromatin landscape of healthy and injured cell types in the human kidney.
Gisch DL, Brennan M, Lake BB, Basta J, Keller MS, Melo Ferreira R, Akilesh S, Ghag R, Lu C, Cheng YH, Collins KS, Parikh SV, Rovin BH, Robbins L, Stout L, Conklin KY, Diep D, Zhang B, Knoten A, Barwinska D, Asghari M, Sabo AR, Ferkowicz MJ, Sutton TA, Kelly KJ, De Boer IH, Rosas SE, Kiryluk K, Hodgin JB, Alakwaa F, Winfree S, Jefferson N, Türkmen A, Gaut JP, Gehlenborg N, Phillips CL, El-Achkar TM, Dagher PC, Hato T, Zhang K, Himmelfarb J, Kretzler M, Mollah S; Kidney Precision Medicine Project (KPMP); Jain S, Rauchman M, Eadon MT. Gisch DL, et al. Among authors: rovin bh. Nat Commun. 2024 Jan 10;15(1):433. doi: 10.1038/s41467-023-44467-6. Nat Commun. 2024. PMID: 38199997 Free PMC article.
KDIGO 2024 Clinical Practice Guideline for the management of LUPUS NEPHRITIS.
Kidney Disease: Improving Global Outcomes (KDIGO) Lupus Nephritis Work Group. Kidney Disease: Improving Global Outcomes (KDIGO) Lupus Nephritis Work Group. Kidney Int. 2024 Jan;105(1S):S1-S69. doi: 10.1016/j.kint.2023.09.002. Kidney Int. 2024. PMID: 38182286 Free article. No abstract available.
Urine and Plasma Complement Ba Levels During Disease Flares in Patients With Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.
Almaani S, Song H, Suthanthira M, Toy C, Fussner LA, Meara A, Nagaraja H, Cuthbertson D, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Warrington KJ, Monach PA, Merkel PA, Rovin B, Birmingham D. Almaani S, et al. Among authors: rovin b. Kidney Int Rep. 2023 Aug 20;8(11):2421-2427. doi: 10.1016/j.ekir.2023.08.017. eCollection 2023 Nov. Kidney Int Rep. 2023. PMID: 38025219 Free PMC article.
Circulating Metabolomic Associations with Neurocognitive Outcomes in Pediatric CKD.
Lee AM, Xu Y, Hooper SR, Abraham AG, Hu J, Xiao R, Matheson MB, Brunson C, Rhee EP, Coresh J, Vasan RS, Schrauben S, Kimmel PL, Warady BA, Furth SL, Hartung EA, Denburg MR; CKD Biomarkers Consortium. Lee AM, et al. Clin J Am Soc Nephrol. 2023 Oct 23;19(1):13-25. doi: 10.2215/CJN.0000000000000318. Online ahead of print. Clin J Am Soc Nephrol. 2023. PMID: 37871960
Association of COVID-19 Versus COVID-19 Vaccination With Kidney Function and Disease Activity in Primary Glomerular Disease: A Report of the Cure Glomerulonephropathy Study.
Wang CS, Glenn DA, Helmuth M, Smith AR, Bomback AS, Canetta PA, Coppock GM, Khalid M, Tuttle KR, Bou-Matar R, Greenbaum LA, Robinson BM, Holzman LB, Smoyer WE, Rheault MN, Gipson D, Mariani LH; Cure Glomerulonephropathy (CureGN) Study Consortium. Wang CS, et al. Am J Kidney Dis. 2024 Jan;83(1):37-46. doi: 10.1053/j.ajkd.2023.07.008. Epub 2023 Aug 31. Am J Kidney Dis. 2024. PMID: 37657635
Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy.
Barbour SJ, Fervenza FC, Induruwage D, Brenchley PE, Rovin B, Hladunewich MA, Reich HN, Lafayette R, Aslam N, Appel GB, Zand L, Kiryluk K, Liu L, Cattran DC; MENTOR Trial Investigators. Barbour SJ, et al. Among authors: rovin b. Clin J Am Soc Nephrol. 2023 Oct 1;18(10):1283-1293. doi: 10.2215/CJN.0000000000000237. Epub 2023 Jul 20. Clin J Am Soc Nephrol. 2023. PMID: 37471101
An atlas of healthy and injured cell states and niches in the human kidney.
Lake BB, Menon R, Winfree S, Hu Q, Melo Ferreira R, Kalhor K, Barwinska D, Otto EA, Ferkowicz M, Diep D, Plongthongkum N, Knoten A, Urata S, Mariani LH, Naik AS, Eddy S, Zhang B, Wu Y, Salamon D, Williams JC, Wang X, Balderrama KS, Hoover PJ, Murray E, Marshall JL, Noel T, Vijayan A, Hartman A, Chen F, Waikar SS, Rosas SE, Wilson FP, Palevsky PM, Kiryluk K, Sedor JR, Toto RD, Parikh CR, Kim EH, Satija R, Greka A, Macosko EZ, Kharchenko PV, Gaut JP, Hodgin JB; KPMP Consortium; Eadon MT, Dagher PC, El-Achkar TM, Zhang K, Kretzler M, Jain S. Lake BB, et al. Nature. 2023 Jul;619(7970):585-594. doi: 10.1038/s41586-023-05769-3. Epub 2023 Jul 19. Nature. 2023. PMID: 37468583 Free PMC article.
Effect of belimumab on kidney-related outcomes in patients with lupus nephritis: post hoc subgroup analyses of the phase 3 BLISS-LN trial.
Anders HJ, Furie R, Malvar A, Zhao MH, Hiromura K, Weinmann-Menke J, Green Y, Jones-Leone A, Negrini D, Levy RA, Lightstone L, Tanaka Y, Rovin BH. Anders HJ, et al. Nephrol Dial Transplant. 2023 Nov 30;38(12):2733-2742. doi: 10.1093/ndt/gfad167. Nephrol Dial Transplant. 2023. PMID: 37463054 Free PMC article. Clinical Trial.
Clinical Outcomes in Patients With Biopsy Proven Anticoagulant-Related Nephropathy.
Dasgupta A, Mikhalina G, Satoskar AA, Biederman L, Nadasdy T, Rovin B, Parikh S, Brodsky SV. Dasgupta A, et al. Among authors: rovin b. Kidney Int Rep. 2023 Apr 24;8(7):1445-1448. doi: 10.1016/j.ekir.2023.04.014. eCollection 2023 Jul. Kidney Int Rep. 2023. PMID: 37441464 Free PMC article. No abstract available.
The chromatin landscape of healthy and injured cell types in the human kidney.
Gisch DL, Brennan M, Lake BB, Basta J, Keller M, Ferreira RM, Akilesh S, Ghag R, Lu C, Cheng YH, Collins KS, Parikh SV, Rovin BH, Robbins L, Conklin KY, Diep D, Zhang B, Knoten A, Barwinska D, Asghari M, Sabo AR, Ferkowicz MJ, Sutton TA, Kelly KJ, Boer IH, Rosas SE, Kiryluk K, Hodgin JB, Alakwaa F, Jefferson N, Gaut JP, Gehlenborg N, Phillips CL, El-Achkar TM, Dagher PC, Hato T, Zhang K, Himmelfarb J, Kretzler M, Mollah S; Kidney Precision Medicine Project (KPMP); Jain S, Rauchman M, Eadon MT. Gisch DL, et al. Among authors: rovin bh. bioRxiv [Preprint]. 2023 Jun 8:2023.06.07.543965. doi: 10.1101/2023.06.07.543965. bioRxiv. 2023. PMID: 37333123 Free PMC article. Updated. Preprint.
Development of American College of Rheumatology Quality Measures for Systemic Lupus Erythematosus: A Modified Delphi Process With Rheumatology Informatics System for Effectiveness (RISE) Registry Data Review.
Bartels CM, Jorge A, Feldman CH, Zell J, Bermas B, Barber CEH, Duarte-García A, Garg S, Haseley L, Jatwani S, Johansson T, Limanni A, Rodgers W, Rovin BH, Santiago-Casas Y, Suter LG, Barnado A, Ude J, Aguirre A, Li J, Schmajuk G, Yazdany J. Bartels CM, et al. Among authors: rovin bh. Arthritis Care Res (Hoboken). 2023 Nov;75(11):2295-2305. doi: 10.1002/acr.25143. Epub 2023 Jun 19. Arthritis Care Res (Hoboken). 2023. PMID: 37165898
Age of Onset and Disease Course in Biopsy-Proven Minimal Change Disease: An Analysis From the Cure Glomerulonephropathy Network.
Chen DP, Helmuth ME, Smith AR, Canetta PA, Ayoub I, Mucha K, Kallash M, Kopp JB, Gbadegesin R, Gillespie BW, Greenbaum LA, Parekh RS, Hunley TE, Sperati CJ, Selewski DT, Kidd J, Chishti A, Reidy K, Mottl AK, Gipson DS, Srivastava T, Twombley KE; CureGN Consortium. Chen DP, et al. Am J Kidney Dis. 2023 Jun;81(6):695-706.e1. doi: 10.1053/j.ajkd.2022.11.012. Epub 2023 Jan 3. Am J Kidney Dis. 2023. PMID: 36608921
Characterization of Glomerular and Tubulointerstitial Proteomes in a Case of Nonsteroidal Anti-Inflammatory Drug-Attributed Acute Kidney Injury: A Clinical Pathologic Molecular Correlation.
Parikh SV, Madhavan S, Shapiro J, Knight R, Rosenberg AZ, Parikh CR, Rovin B, Menez S; Kidney Precision Medicine Project. Parikh SV, et al. Among authors: rovin b. Clin J Am Soc Nephrol. 2023 Mar 1;18(3):402-410. doi: 10.2215/CJN.09260822. Epub 2023 Jan 30. Clin J Am Soc Nephrol. 2023. PMID: 36344211 Free PMC article.
Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease.
Liu J, Nair V, Zhao YY, Chang DY, Limonte C, Bansal N, Fermin D, Eichinger F, Tanner EC, Bellovich KA, Steigerwalt S, Bhat Z, Hawkins JJ, Subramanian L, Rosas SE, Sedor JR, Vasquez MA, Waikar SS, Bitzer M, Pennathur S, Brosius FC, De Boer I, Chen M, Kretzler M, Ju W; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group; Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group. Liu J, et al. Diabetes. 2022 Dec 1;71(12):2664-2676. doi: 10.2337/db22-0169. Diabetes. 2022. PMID: 36331122 Free PMC article.
Results from part A of the multi-center, double-blind, randomized, placebo-controlled NefIgArd trial, which evaluated targeted-release formulation of budesonide for the treatment of primary immunoglobulin A nephropathy.
Barratt J, Lafayette R, Kristensen J, Stone A, Cattran D, Floege J, Tesar V, Trimarchi H, Zhang H, Eren N, Paliege A, Rovin BH; NefIgArd Trial Investigators. Barratt J, et al. Kidney Int. 2023 Feb;103(2):391-402. doi: 10.1016/j.kint.2022.09.017. Epub 2022 Oct 19. Kidney Int. 2023. PMID: 36270561 Free article. Clinical Trial.
Racial and Ethnic Disparities in Acute Care Utilization Among Patients With Glomerular Disease.
Krissberg JR, O'Shaughnessy MM, Smith AR, Helmuth ME, Almaani S, Aviles DH, Brathwaite KE, Cai Y, Cattran D, Gbadegesin R, Glenn DA, Greenbaum LA, Iragorri S, Jain K, Khalid M, Kidd J, Kopp J, Lafayette R, Lane JC, Lugani F, Nestor JG, Parekh RS, Reidy K, Selewski DT, Sethna CB, Sperati CJ, Tuttle K, Twombley K, Vasylyeva TL, Weaver DJ Jr, Wenderfer SE, Gibson K; CureGN Consortium. Krissberg JR, et al. Am J Kidney Dis. 2023 Mar;81(3):318-328.e1. doi: 10.1053/j.ajkd.2022.08.010. Epub 2022 Oct 1. Am J Kidney Dis. 2023. PMID: 36191724 Free PMC article.
International Physicians Delphi Survey: Managing Patients With IgA Nephropathy.
Floege J, Barratt J, Coppo R, Lafayette R, Radhakrishnan J, Reich HN, Rovin BH, Selewski DT, Vivarelli M, Pham C, Tesař V. Floege J, et al. Kidney Int Rep. 2022 May 26;7(9):2076-2080. doi: 10.1016/j.ekir.2022.05.022. eCollection 2022 Sep. Kidney Int Rep. 2022. PMID: 36090484 Free PMC article. No abstract available.
A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology.
Lutnick B, Manthey D, Becker JU, Ginley B, Moos K, Zuckerman JE, Rodrigues L, Gallan AJ, Barisoni L, Alpers CE, Wang XX, Myakala K, Jones BA, Levi M, Kopp JB, Yoshida T, Zee J, Han SS, Jain S, Rosenberg AZ, Jen KY, Sarder P; Kidney Precision Medicine Project. Lutnick B, et al. Commun Med (Lond). 2022 Aug 19;2:105. doi: 10.1038/s43856-022-00138-z. eCollection 2022. Commun Med (Lond). 2022. PMID: 35996627 Free PMC article.
Molecular profiling of kidney compartments from serial biopsies differentiate treatment responders from non-responders in lupus nephritis.
Parikh SV, Malvar A, Song H, Shapiro J, Mejia-Vilet JM, Ayoub I, Almaani S, Madhavan S, Alberton V, Besso C, Lococo B, Satoskar A, Zhang J, Yu L, Fadda P, Eadon M, Birmingham D, Ganesan LP, Jarjour W, Rovin BH. Parikh SV, et al. Among authors: rovin bh. Kidney Int. 2022 Oct;102(4):845-865. doi: 10.1016/j.kint.2022.05.033. Epub 2022 Jul 2. Kidney Int. 2022. PMID: 35788359 Free PMC article.
A reference tissue atlas for the human kidney.
Hansen J, Sealfon R, Menon R, Eadon MT, Lake BB, Steck B, Anjani K, Parikh S, Sigdel TK, Zhang G, Velickovic D, Barwinska D, Alexandrov T, Dobi D, Rashmi P, Otto EA, Rivera M, Rose MP, Anderton CR, Shapiro JP, Pamreddy A, Winfree S, Xiong Y, He Y, de Boer IH, Hodgin JB, Barisoni L, Naik AS, Sharma K, Sarwal MM, Zhang K, Himmelfarb J, Rovin B, El-Achkar TM, Laszik Z, He JC, Dagher PC, Valerius MT, Jain S, Satlin LM, Troyanskaya OG, Kretzler M, Iyengar R, Azeloglu EU; Kidney Precision Medicine Project. Hansen J, et al. Among authors: rovin b. Sci Adv. 2022 Jun 10;8(23):eabn4965. doi: 10.1126/sciadv.abn4965. Epub 2022 Jun 8. Sci Adv. 2022. PMID: 35675394 Free PMC article.
A challenge to the kidney community by a man-made crisis.
Coates PT, Wong G, Rovin BH, Ronco P; Entire Editorial and Management Team. Coates PT, et al. Kidney Int. 2022 May;101(5):854-855. doi: 10.1016/j.kint.2022.03.017. Kidney Int. 2022. PMID: 35461610 No abstract available.
Association of Uremic Solutes With Cardiovascular Death in Diabetic Kidney Disease.
Sapa H, Gutiérrez OM, Shlipak MG, Katz R, Ix JH, Sarnak MJ, Cushman M, Rhee EP, Kimmel PL, Vasan RS, Schrauben SJ, Feldman HI, Seegmiller JC, Brunengraber H, Hostetter TH, Schelling JR; CKD Biomarkers Consortium. Sapa H, et al. Am J Kidney Dis. 2022 Oct;80(4):502-512.e1. doi: 10.1053/j.ajkd.2022.02.016. Epub 2022 Mar 26. Am J Kidney Dis. 2022. PMID: 35351578 Free PMC article.
Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation.
Menon R, Bomback AS, Lake BB, Stutzke C, Grewenow SM, Menez S, D'Agati VD, Jain S; Kidney Precision Medicine Project. Menon R, et al. Kidney Int. 2022 Jun;101(6):1116-1125. doi: 10.1016/j.kint.2022.03.011. Epub 2022 Mar 23. Kidney Int. 2022. PMID: 35339536 Free PMC article. No abstract available.
Longitudinal TNFR1 and TNFR2 and Kidney Outcomes: Results from AASK and VA NEPHRON-D.
Chen TK, Coca SG, Estrella MM, Appel LJ, Coresh J, Thiessen Philbrook H, Obeid W, Fried LF, Heerspink HJL, Ix JH, Shlipak MG, Kimmel PL, Parikh CR, Grams ME; CKD Biomarkers Consortium (BioCon). Chen TK, et al. J Am Soc Nephrol. 2022 May;33(5):996-1010. doi: 10.1681/ASN.2021060735. Epub 2022 Mar 21. J Am Soc Nephrol. 2022. PMID: 35314457 Free PMC article.
A Focus Group Study of Self-Management in Patients With Glomerular Disease.
Carter SA, Teng C, Gutman T, Logeman C, Cattran D, Lightstone L, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster DJ, Coppo R, Fervenza FC, Floege J, Hladunewich MA, Hogan JJ, Kitching AR, Lafayette RA, Malvar A, Radhakrishnan J, Rovin BH, Scholes-Robertson N, Trimarchi H, Zhang H, Azukaitis K, Cho Y, Viecelli AK, Dunn L, Harris D, Johnson DW, Kerr PG, Laboi P, Ryan J, Shen JI, Ruiz L, Wang AY, Lee AHK, Ka Shun SF, Ka-Hang Tong M, Teixeira-Pinto A, Wilkie M, Alexander SI, Craig JC, Martin A, Tong A. Carter SA, et al. Kidney Int Rep. 2021 Oct 30;7(1):56-67. doi: 10.1016/j.ekir.2021.10.011. eCollection 2022 Jan. Kidney Int Rep. 2021. PMID: 35005314 Free PMC article.
A Core Outcome Set for Trials in Glomerular Disease: A Report of the Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD) Stakeholder Workshops.
Carter SA, Lightstone L, Cattran D, Tong A, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster DJ, Coppo R, Fervenza FC, Floege J, Hladunewich MA, Hogan JJ, Kitching AR, Lafayette RA, Malvar A, Radhakrishnan J, Rovin BH, Scholes-Robertson N, Trimarchi H, Zhang H, Anumudu S, Cho Y, Gutman T, O'Lone E, Viecelli AK, Au E, Azukaitis K, Baumgart A, Bernier-Jean A, Dunn L, Howell M, Ju A, Logeman C, Nataatmadja M, Sautenet B, Sharma A, Craig JC; SONG-GD Workshop Investigators. Carter SA, et al. Among authors: rovin bh. Clin J Am Soc Nephrol. 2022 Jan;17(1):53-64. doi: 10.2215/CJN.07840621. Epub 2021 Dec 30. Clin J Am Soc Nephrol. 2022. PMID: 34969698 Free PMC article.
A Participant-Centered Approach to Understanding Risks and Benefits of Participation in Research Informed by the Kidney Precision Medicine Project.
Butler CR, Appelbaum PS, Ascani H, Aulisio M, Campbell CE, de Boer IH, Dighe AL, Hall DE, Himmelfarb J, Knight R, Mehl K, Murugan R, Rosas SE, Sedor JR, O'Toole JF, Tuttle KR, Waikar SS, Freeman M; Kidney Precision Medicine Project. Butler CR, et al. Am J Kidney Dis. 2022 Jul;80(1):132-138. doi: 10.1053/j.ajkd.2021.10.006. Epub 2021 Dec 4. Am J Kidney Dis. 2022. PMID: 34871700 Free PMC article.
Prediction models of treatment response in lupus nephritis.
Ayoub I, Wolf BJ, Geng L, Song H, Khatiwada A, Tsao BP, Oates JC, Rovin BH. Ayoub I, et al. Kidney Int. 2022 Feb;101(2):379-389. doi: 10.1016/j.kint.2021.11.014. Epub 2021 Dec 3. Kidney Int. 2022. PMID: 34871620 Free PMC article.
Can Antinuclear Antibodies (ANA) be Monoclonal?
Biederman L, Satoskar AA, Doraiswamy M, Parikh S, Rovin B, Mussio B, Mikhalina G, Brodsky SV. Biederman L, et al. Among authors: rovin b. Case Rep Nephrol. 2021 Sep 30;2021:7006466. doi: 10.1155/2021/7006466. eCollection 2021. Case Rep Nephrol. 2021. PMID: 34631181 Free PMC article.
The lupus nephritis management renaissance.
Mejia-Vilet JM, Malvar A, Arazi A, Rovin BH. Mejia-Vilet JM, et al. Kidney Int. 2022 Feb;101(2):242-255. doi: 10.1016/j.kint.2021.09.012. Epub 2021 Oct 4. Kidney Int. 2022. PMID: 34619230 Review.
B-cell depletion with obinutuzumab for the treatment of proliferative lupus nephritis: a randomised, double-blind, placebo-controlled trial.
Furie RA, Aroca G, Cascino MD, Garg JP, Rovin BH, Alvarez A, Fragoso-Loyo H, Zuta-Santillan E, Schindler T, Brunetta P, Looney CM, Hassan I, Malvar A. Furie RA, et al. Ann Rheum Dis. 2022 Jan;81(1):100-107. doi: 10.1136/annrheumdis-2021-220920. Epub 2021 Oct 6. Ann Rheum Dis. 2022. PMID: 34615636 Free PMC article. Clinical Trial.
Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation.
Bomback AS, Appel GB, Gipson DS, Hladunewich MA, Lafayette R, Nester CM, Parikh SV, Smith RJH, Trachtman H, Heeger PS, Ram S, Rovin BH, Ali S, Arceneaux N, Ashoor I, Bailey-Wickins L, Barratt J, Beck L, Cattran DC, Cravedi P, Erkan E, Fervenza F, Frazer-Abel AA, Fremeaux-Bacchi V, Fuller L, Gbadegesin R, Hogan JJ, Kiryluk K, le Quintrec-Donnette M, Licht C, Mahan JD, Pickering MC, Quigg R, Rheault M, Ronco P, Sarwal MM, Sethna C, Spino C, Stegall M, Vivarelli M, Feldman DL, Thurman JM. Bomback AS, et al. Among authors: rovin bh. Am J Kidney Dis. 2022 Apr;79(4):570-581. doi: 10.1053/j.ajkd.2021.07.025. Epub 2021 Sep 24. Am J Kidney Dis. 2022. PMID: 34571062
A secondary analysis of the Belimumab International Study in Lupus Nephritis trial examined effects of belimumab on kidney outcomes and preservation of kidney function in patients with lupus nephritis.
Rovin BH, Furie R, Teng YKO, Contreras G, Malvar A, Yu X, Ji B, Green Y, Gonzalez-Rivera T, Bass D, Gilbride J, Tang CH, Roth DA. Rovin BH, et al. Kidney Int. 2022 Feb;101(2):403-413. doi: 10.1016/j.kint.2021.08.027. Epub 2021 Sep 22. Kidney Int. 2022. PMID: 34560137 Free article. Clinical Trial.
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mejía-Vilet JM, Nester CM, Radhakrishnan J, Rave EM, Reich HN, Ronco P, Sanders JF, Sethi S, Suzuki Y, Tang SCW, Tesar V, Vivarelli M, Wetzels JFM, Lytvyn L, Craig JC, Tunnicliffe DJ, Howell M, Tonelli MA, Cheung M, Earley A, Floege J. Rovin BH, et al. Kidney Int. 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015. Kidney Int. 2021. PMID: 34556300 Free article.
KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases.
Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group. Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group. Kidney Int. 2021 Oct;100(4S):S1-S276. doi: 10.1016/j.kint.2021.05.021. Kidney Int. 2021. PMID: 34556256 Free article. No abstract available.
Urine Biomarkers of Kidney Tubule Health, Injury, and Inflammation are Associated with Progression of CKD in Children.
Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Ix JH, Jogalekar MP, Coca S, Waikar SS, Shlipak MG, Warady BA, Vasan RS, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S; CKD Biomarkers Consortium; CKD Biomarker consortium. Greenberg JH, et al. J Am Soc Nephrol. 2021 Oct;32(10):2664-2677. doi: 10.1681/ASN.2021010094. Epub 2021 Sep 20. J Am Soc Nephrol. 2021. PMID: 34544821 Free PMC article.
Natural antibody and complement activation characterize patients with idiopathic nephrotic syndrome.
Trachtman H, Laskowski J, Lee C, Renner B, Feemster A, Parikh S, Panzer SE, Zhong W, Cravedi P, Cantarelli C, Kulik L, You Z, Satchell S, Rovin B, Liu F, Kalled SL, Holers VM, Jalal D, Thurman JM. Trachtman H, et al. Among authors: rovin b. Am J Physiol Renal Physiol. 2021 Oct 1;321(4):F505-F516. doi: 10.1152/ajprenal.00041.2021. Epub 2021 Aug 30. Am J Physiol Renal Physiol. 2021. PMID: 34459222 Free PMC article.
Metabolite Biomarkers of CKD Progression in Children.
Denburg MR, Xu Y, Abraham AG, Coresh J, Chen J, Grams ME, Feldman HI, Kimmel PL, Rebholz CM, Rhee EP, Vasan RS, Warady BA, Furth SL; CKD Biomarkers Consortium. Denburg MR, et al. Clin J Am Soc Nephrol. 2021 Aug;16(8):1178-1189. doi: 10.2215/CJN.00220121. Clin J Am Soc Nephrol. 2021. PMID: 34362785 Free PMC article.
Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis.
Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS; Kidney Precision Medicine Project (KPMP). Schmidt IM, et al. Kidney Int. 2021 Sep;100(3):672-683. doi: 10.1016/j.kint.2021.04.037. Epub 2021 May 27. Kidney Int. 2021. PMID: 34051265 Free PMC article.
Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.
Rovin BH, Teng YKO, Ginzler EM, Arriens C, Caster DJ, Romero-Diaz J, Gibson K, Kaplan J, Lisk L, Navarra S, Parikh SV, Randhawa S, Solomons N, Huizinga RB. Rovin BH, et al. Lancet. 2021 May 29;397(10289):2070-2080. doi: 10.1016/S0140-6736(21)00578-X. Epub 2021 May 7. Lancet. 2021. PMID: 33971155 Clinical Trial.
Development of an international Delphi survey to establish core outcome domains for trials in adults with glomerular disease.
Carter SA, Logeman C, Howell M, Cattran D, Lightstone L, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster DJ, Coppo R, Fervenza FC, Floege J, Hladunewich MA, Hogan JJ, Kitching AR, Lafayette RA, Malvar A, Radhakrishnan J, Rovin BH, Scholes-Robertson N, Trimarchi H, Zhang H, Cho Y, Dunn L, Gipson DS, Liew A, Sautenet B, Viecelli AK, Harris D, Johnson DW, Wang AY, Teixeira-Pinto A, Alexander SI, Martin A, Tong A, Craig JC. Carter SA, et al. Among authors: rovin bh. Kidney Int. 2021 Oct;100(4):881-893. doi: 10.1016/j.kint.2021.04.027. Epub 2021 May 5. Kidney Int. 2021. PMID: 33964313
The authors reply.
Anders HJ, Lei Y, Rovin BH. Anders HJ, et al. Kidney Int. 2021 May;99(5):1242. doi: 10.1016/j.kint.2021.02.011. Kidney Int. 2021. PMID: 33892864 No abstract available.
Limited Significance of Antifactor H Antibodies in Patients with Membranous Nephropathy.
Sethi A, Miao J, Willrich MAV, Frinack JL, Cattran DC, Fervenza FC; MENTOR study Investigators; MENTOR study investigators. Sethi A, et al. Clin J Am Soc Nephrol. 2021 Jun;16(6):939-941. doi: 10.2215/CJN.16631020. Epub 2021 Apr 15. Clin J Am Soc Nephrol. 2021. PMID: 33858828 Free PMC article. No abstract available.
Looking back and moving forward.
Ronco P, Rovin BH; Entire Editorial and Management Team. Ronco P, et al. Kidney Int. 2021 Apr;99(4):787-790. doi: 10.1016/j.kint.2021.02.001. Kidney Int. 2021. PMID: 33745543 No abstract available.
A Novel Inflammatory Dendritic Cell That Is Abundant and Contiguous to T Cells in the Kidneys of Patients With Lupus Nephritis.
Parikh SV, Malvar A, Shapiro J, Turman JM, Song H, Alberton V, Lococo B, Mejia-Vilet JM, Madhavan S, Zhang J, Yu L, Satoskar AA, Birmingham D, Jarjour WN, Rovin BH, Ganesan LP. Parikh SV, et al. Among authors: rovin bh. Front Immunol. 2021 Feb 17;12:621039. doi: 10.3389/fimmu.2021.621039. eCollection 2021. Front Immunol. 2021. PMID: 33659005 Free PMC article.
Innovating and invigorating the clinical trial infrastructure for glomerular diseases.
Barisoni L, Barratt J, Campbell K, Eva L, Gillespie BS, Gipson D, Huber T, Jardine M, Kamil E, Kretzler M, Lee L, Levtchenk E, Mehr AP, Nachman PH, Oh J, Saleem M, Shankland SJ, Smith K, Smokler I, Smoyer W, Tarnoff J, Thompson A, Trachtman H, Udani S, Vivarelli M, Walker P, West M, Rovin BH. Barisoni L, et al. Kidney Int. 2021 Mar;99(3):519-523. doi: 10.1016/j.kint.2020.09.038. Kidney Int. 2021. PMID: 33637197 No abstract available.
Patient perspectives and involvement in precision medicine research.
Tuttle KR, Bebiak J, Brown K, Campbell C, Dighe A, Hyashi L, Jefferson N, Roberts GV, Stutzke C, Knight R; Kidney Precision Medicine Project. Tuttle KR, et al. Kidney Int. 2021 Mar;99(3):511-514. doi: 10.1016/j.kint.2020.10.036. Kidney Int. 2021. PMID: 33637195
Rationale and design of the Kidney Precision Medicine Project.
de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J; Kidney Precision Medicine Project. de Boer IH, et al. Kidney Int. 2021 Mar;99(3):498-510. doi: 10.1016/j.kint.2020.08.039. Kidney Int. 2021. PMID: 33637194 Free PMC article.
Establishing a Case for Anti-complement Therapy in Membranous Nephropathy.
Ayoub I, Shapiro JP, Song H, Zhang XL, Parikh S, Almaani S, Madhavan S, Brodsky SV, Satoskar A, Bott C, Yu L, Merchant M, Klein J, Mejia-Vilet JM, Nadasdy T, Birmingham D, Rovin BH. Ayoub I, et al. Kidney Int Rep. 2020 Dec 13;6(2):484-492. doi: 10.1016/j.ekir.2020.11.032. eCollection 2021 Feb. Kidney Int Rep. 2020. PMID: 33615073 Free PMC article.
Avacopan for the Treatment of ANCA-Associated Vasculitis.
Jayne DRW, Merkel PA, Schall TJ, Bekker P; ADVOCATE Study Group. Jayne DRW, et al. N Engl J Med. 2021 Feb 18;384(7):599-609. doi: 10.1056/NEJMoa2023386. N Engl J Med. 2021. PMID: 33596356 Clinical Trial.
Molecular characterization of the human kidney interstitium in health and disease.
Barwinska D, El-Achkar TM, Melo Ferreira R, Syed F, Cheng YH, Winfree S, Ferkowicz MJ, Hato T, Collins KS, Dunn KW, Kelly KJ, Sutton TA, Rovin BH, Parikh SV, Phillips CL, Dagher PC, Eadon MT; Kidney Precision Medicine Project. Barwinska D, et al. Sci Adv. 2021 Feb 10;7(7):eabd3359. doi: 10.1126/sciadv.abd3359. Print 2021 Feb. Sci Adv. 2021. PMID: 33568476 Free PMC article.
The ALPHA Project: Establishing consensus and prioritisation of global community recommendations to address major challenges in lupus diagnosis, care, treatment and research.
Tse K, Sangodkar S, Bloch L, Arntsen K, Bae SC, Bruce IN, Connolly-Strong E, Costenbader KH, Dickerson B, Dörner T, Evans S, Kalunian K, Kao AH, Manzi S, Morand EF, Raymond SC, Rovin BH, Schanberg LE, Von Feldt JM, Werth VP, Williams Derricott A, Zook D, Franson T, Getz K, Peña Y, Hanrahan LM; ALPHA Project Global Advisory Committee. Tse K, et al. Among authors: rovin bh. Lupus Sci Med. 2021 Feb;8(1):e000433. doi: 10.1136/lupus-2020-000433. Lupus Sci Med. 2021. PMID: 33563729 Free PMC article.
Belimumab in Lupus Nephritis. Reply.
Furie R, Rovin BH, Roth DA. Furie R, et al. N Engl J Med. 2021 Jan 14;384(2):188. doi: 10.1056/NEJMc2032520. N Engl J Med. 2021. PMID: 33497559 No abstract available.
In this issue-2020 draws to a close.
Rovin BH. Rovin BH. Kidney Int. 2020 Dec;98(6):1361. doi: 10.1016/j.kint.2020.10.011. Kidney Int. 2020. PMID: 33276858 Free PMC article. No abstract available.
Integrating Patient Priorities with Science by Community Engagement in the Kidney Precision Medicine Project.
Tuttle KR, Knight R, Appelbaum PS, Arora T, Bansal S, Bebiak J, Brown K, Campbell C, Cooperman L, Corona-Villalobos CP, Dighe A, de Boer IH, Hall DE, Jefferson N, Jolly S, Kermani A, Lee SC, Mehl K, Murugan R, Roberts GV, Rosas SE, Himmelfarb J, Miller RT; Kidney Precision Medicine Project. Tuttle KR, et al. Clin J Am Soc Nephrol. 2021 Apr 7;16(4):660-668. doi: 10.2215/CJN.10270620. Epub 2020 Nov 30. Clin J Am Soc Nephrol. 2021. PMID: 33257411 Free PMC article.
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.
El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. El-Achkar TM, et al. Among authors: rovin bh. Physiol Genomics. 2021 Jan 1;53(1):1-11. doi: 10.1152/physiolgenomics.00104.2020. Epub 2020 Nov 16. Physiol Genomics. 2021. PMID: 33197228 Free PMC article.
Letter to the Editor.
Almaani S, De Rosa M, Rovin BH. Almaani S, et al. Kidney Int Rep. 2020 Aug 28;5(11):2121. doi: 10.1016/j.ekir.2020.08.024. eCollection 2020 Nov. Kidney Int Rep. 2020. PMID: 33186416 Free PMC article. No abstract available.
Why Target the Gut to Treat IgA Nephropathy?
Barratt J, Rovin BH, Cattran D, Floege J, Lafayette R, Tesar V, Trimarchi H, Zhang H; NefIgArd Study Steering Committee. Barratt J, et al. Kidney Int Rep. 2020 Aug 20;5(10):1620-1624. doi: 10.1016/j.ekir.2020.08.009. eCollection 2020 Oct. Kidney Int Rep. 2020. PMID: 33102954 Free PMC article. No abstract available.
Systematic Review and Meta-Analysis of Native Kidney Biopsy Complications.
Poggio ED, McClelland RL, Blank KN, Hansen S, Bansal S, Bomback AS, Canetta PA, Khairallah P, Kiryluk K, Lecker SH, McMahon GM, Palevsky PM, Parikh S, Rosas SE, Tuttle K, Vazquez MA, Vijayan A, Rovin BH; Kidney Precision Medicine Project. Poggio ED, et al. Clin J Am Soc Nephrol. 2020 Nov 6;15(11):1595-1602. doi: 10.2215/CJN.04710420. Epub 2020 Oct 15. Clin J Am Soc Nephrol. 2020. PMID: 33060160 Free PMC article.
Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.
Furie R, Rovin BH, Houssiau F, Malvar A, Teng YKO, Contreras G, Amoura Z, Yu X, Mok CC, Santiago MB, Saxena A, Green Y, Ji B, Kleoudis C, Burriss SW, Barnett C, Roth DA. Furie R, et al. Among authors: rovin bh. N Engl J Med. 2020 Sep 17;383(12):1117-1128. doi: 10.1056/NEJMoa2001180. N Engl J Med. 2020. PMID: 32937045 Clinical Trial.
Assessing the Impact of Losmapimod on Proteinuria in Idiopathic Focal Segmental Glomerulosclerosis.
Gipson DS, Hladunewich MA, Lafayette R, Sedor JR, Rovin BH, Barbour SJ, McMahon A, Jennette JC, Nachman PH, Willette RN, Paglione M, Gao F, Ross Terres JA, Vallow S, Holland MC, Thorneloe KS, Sprecher DL. Gipson DS, et al. Kidney Int Rep. 2020 May 26;5(8):1228-1239. doi: 10.1016/j.ekir.2020.05.024. eCollection 2020 Aug. Kidney Int Rep. 2020. PMID: 32775822 Free PMC article.
A tolvaptan skeptic repents.
Rovin BH. Rovin BH. Kidney Int. 2020 Aug;98(2):293. doi: 10.1016/j.kint.2020.04.005. Kidney Int. 2020. PMID: 32709291 No abstract available.
Persistent Disease Activity in Patients With Long-Standing Glomerular Disease.
Delbarba E, Marasa M, Canetta PA, Piva SE, Chatterjee D, Kil BH, Mu X, Gibson KL, Hladunewich MA, Hogan JJ, Julian BA, Kidd JM, Laurin LP, Nachman PH, Rheault MN, Rizk DV, Sanghani NS, Trachtman H, Wenderfer SE, Gharavi AG, Bomback AS; CureGN Consortium. Delbarba E, et al. Kidney Int Rep. 2020 Mar 20;5(6):860-871. doi: 10.1016/j.ekir.2020.03.017. eCollection 2020 Jun. Kidney Int Rep. 2020. PMID: 32518868 Free PMC article.
Identifying Outcomes Important to Patients with Glomerular Disease and Their Caregivers.
Carter SA, Gutman T, Logeman C, Cattran D, Lightstone L, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster D, Coppo R, Fervenza FC, Floege J, Hladunewich M, Hogan JJ, Kitching AR, Lafayette RA, Malvar A, Radhakrishnan J, Rovin BH, Scholes-Robertson N, Trimarchi H, Zhang H, Azukaitis K, Cho Y, Viecelli AK, Dunn L, Harris D, Johnson DW, Kerr PG, Laboi P, Ryan J, Shen JI, Ruiz L, Wang AY, Lee AHK, Fung S, Tong MK, Teixeira-Pinto A, Wilkie M, Alexander SI, Craig JC, Tong A; SONG-GD Investigators. Carter SA, et al. Clin J Am Soc Nephrol. 2020 May 7;15(5):673-684. doi: 10.2215/CJN.13101019. Epub 2020 Apr 30. Clin J Am Soc Nephrol. 2020. PMID: 32354728 Free PMC article.
Early experience with COVID-19 in kidney transplantation.
Coates PT, Wong G, Drueke T, Rovin B, Ronco P; Associate Editors, for the Entire Editorial Team. Coates PT, et al. Among authors: rovin b. Kidney Int. 2020 Jun;97(6):1074-1075. doi: 10.1016/j.kint.2020.04.001. Epub 2020 Apr 9. Kidney Int. 2020. PMID: 32354635 Free PMC article. No abstract available.
Kidney International and the COVID-19 infection.
Rovin BH, Ronco P; Associate Editors; Entire Editorial Team. Rovin BH, et al. Kidney Int. 2020 May;97(5):823. doi: 10.1016/j.kint.2020.03.010. Epub 2020 Mar 26. Kidney Int. 2020. PMID: 32284224 Free PMC article. No abstract available.
Membranous Nephropathy With Crescents.
Alawieh R, Brodsky SV, Satoskar AA, Nadasdy T, Parikh SV, Rovin B, Cassol CA. Alawieh R, et al. Among authors: rovin b. Kidney Int Rep. 2020 Jan 30;5(4):537-541. doi: 10.1016/j.ekir.2020.01.010. eCollection 2020 Apr. Kidney Int Rep. 2020. PMID: 32274459 Free PMC article. No abstract available.
Update on Lupus Nephritis: Core Curriculum 2020.
Parikh SV, Almaani S, Brodsky S, Rovin BH. Parikh SV, et al. Am J Kidney Dis. 2020 Aug;76(2):265-281. doi: 10.1053/j.ajkd.2019.10.017. Epub 2020 Mar 24. Am J Kidney Dis. 2020. PMID: 32220510 Review.
The authors reply.
Malvar A, Rovin BH. Malvar A, et al. Kidney Int. 2020 Apr;97(4):807. doi: 10.1016/j.kint.2020.01.010. Kidney Int. 2020. PMID: 32200867 Free article. No abstract available.
Systemic autoimmune diseases and the kidney.
Rovin BH. Rovin BH. Kidney Int. 2020 Feb;97(2):222-225. doi: 10.1016/j.kint.2019.11.002. Kidney Int. 2020. PMID: 31980066 Free article. No abstract available.
Do kidneys grow old gracefully?
Rovin BH. Rovin BH. Kidney Int. 2020 Jan;97(1):40-41. doi: 10.1016/j.kint.2019.08.031. Kidney Int. 2020. PMID: 31901356 Free article. No abstract available.
Development of a Set of Lupus-Specific, Ambulatory Care-Sensitive, Potentially Preventable Adverse Conditions: A Delphi Consensus Study.
Feldman CH, Speyer C, Ashby R, L Bermas B, Bhattacharyya S, Chakravarty E, Everett B, Ferucci E, Hersh AO, Marty FM, Merola JF, Ramsey-Goldman R, Rovin BH, Son MB, Tarter L, Waikar S, Yazdany J, Weissman JS, Costenbader KH. Feldman CH, et al. Among authors: rovin bh. Arthritis Care Res (Hoboken). 2021 Jan;73(1):146-157. doi: 10.1002/acr.24095. Arthritis Care Res (Hoboken). 2021. PMID: 31628721 Free PMC article. Review.
Rethinking Lupus Nephritis Classification on a Molecular Level.
Almaani S, Prokopec SD, Zhang J, Yu L, Avila-Casado C, Wither J, Scholey JW, Alberton V, Malvar A, Parikh SV, Boutros PC, Rovin BH, Reich HN. Almaani S, et al. J Clin Med. 2019 Sep 23;8(10):1524. doi: 10.3390/jcm8101524. J Clin Med. 2019. PMID: 31547518 Free PMC article.
Global consensus building and prioritisation of fundamental lupus challenges: the ALPHA project.
Manzi S, Raymond S, Tse K, Peña Y, Anderson A, Arntsen K, Bae SC, Bruce I, Dörner T, Getz K, Hanrahan L, Kao A, Morand E, Rovin B, Schanberg LE, Von Feldt JM, Werth VP, Costenbader K. Manzi S, et al. Among authors: rovin b. Lupus Sci Med. 2019 Jul 19;6(1):e000342. doi: 10.1136/lupus-2019-000342. eCollection 2019. Lupus Sci Med. 2019. PMID: 31413854 Free PMC article.
Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy.
Fervenza FC, Appel GB, Barbour SJ, Rovin BH, Lafayette RA, Aslam N, Jefferson JA, Gipson PE, Rizk DV, Sedor JR, Simon JF, McCarthy ET, Brenchley P, Sethi S, Avila-Casado C, Beanlands H, Lieske JC, Philibert D, Li T, Thomas LF, Green DF, Juncos LA, Beara-Lasic L, Blumenthal SS, Sussman AN, Erickson SB, Hladunewich M, Canetta PA, Hebert LA, Leung N, Radhakrishnan J, Reich HN, Parikh SV, Gipson DS, Lee DK, da Costa BR, Jüni P, Cattran DC; MENTOR Investigators. Fervenza FC, et al. Among authors: rovin bh. N Engl J Med. 2019 Jul 4;381(1):36-46. doi: 10.1056/NEJMoa1814427. N Engl J Med. 2019. PMID: 31269364 Clinical Trial.
Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease.
Carter SA, Lightstone L, Cattran D, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster D, Coppo R, Fervenza FC, Floege J, Hladunewich M, Hogan JJ, Kitching AR, Lafayette R, Malvar A, Radhakrishnan J, Rovin BH, Zhang H, Gutman T, Howell M, Logeman C, Shen JI, Teixeira-Pinto A, Alexander SI, Cho Y, Craig JC, Harris D, Johnson DW, Kerr PG, Ryan J, Viecelli AK, Wang AY, Wilkie M, Scholes-Robertson N, Tong A; SONG-GD Initiative. Carter SA, et al. Kidney Int. 2019 Jun;95(6):1280-1283. doi: 10.1016/j.kint.2019.01.047. Kidney Int. 2019. PMID: 31122702 Free PMC article. No abstract available.
The authors reply.
Rovin BH, Solomons N, Huizinga RB. Rovin BH, et al. Kidney Int. 2019 Apr;95(4):992-993. doi: 10.1016/j.kint.2018.12.010. Kidney Int. 2019. PMID: 30904071 Free article. No abstract available.
Health-related quality of life in glomerular disease.
Canetta PA, Troost JP, Mahoney S, Kogon AJ, Carlozzi N, Bartosh SM, Cai Y, Davis TK, Fernandez H, Fornoni A, Gbadegesin RA, Herreshoff E, Mahan JD, Nachman PH, Selewski DT, Sethna CB, Srivastava T, Tuttle KR, Wang CS, Falk RJ, Gharavi AG, Gillespie BW, Greenbaum LA, Holzman LB, Kretzler M, Robinson BM, Smoyer WE, Guay-Woodford LM, Reeve B, Gipson DS; CureGN Consortium. Canetta PA, et al. Kidney Int. 2019 May;95(5):1209-1224. doi: 10.1016/j.kint.2018.12.018. Epub 2019 Feb 27. Kidney Int. 2019. PMID: 30898342 Free PMC article.
Citius, altius, fortius . . . . faster, higher, stronger.
Ronco P, Rovin B; Associate Editors; Entire Editorial Team. Ronco P, et al. Among authors: rovin b. Kidney Int. 2019 Mar;95(3):476-478. doi: 10.1016/j.kint.2019.01.001. Kidney Int. 2019. PMID: 30784651 Free article. No abstract available.
Response to: 'ANA testing in "real life"' by Infantino etal.
Pisetsky DS, Spencer DM, Lipsky PE, Rovin BH. Pisetsky DS, et al. Ann Rheum Dis. 2020 Jan;79(1):e4. doi: 10.1136/annrheumdis-2018-214650. Epub 2018 Nov 17. Ann Rheum Dis. 2020. PMID: 30448767 No abstract available.
A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis.
Rovin BH, Solomons N, Pendergraft WF 3rd, Dooley MA, Tumlin J, Romero-Diaz J, Lysenko L, Navarra SV, Huizinga RB; AURA-LV Study Group. Rovin BH, et al. Kidney Int. 2019 Jan;95(1):219-231. doi: 10.1016/j.kint.2018.08.025. Epub 2018 Nov 9. Kidney Int. 2019. PMID: 30420324 Free article. Clinical Trial.
CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease.
Mariani LH, Bomback AS, Canetta PA, Flessner MF, Helmuth M, Hladunewich MA, Hogan JJ, Kiryluk K, Nachman PH, Nast CC, Rheault MN, Rizk DV, Trachtman H, Wenderfer SE, Bowers C, Hill-Callahan P, Marasa M, Poulton CJ, Revell A, Vento S, Barisoni L, Cattran D, D'Agati V, Jennette JC, Klein JB, Laurin LP, Twombley K, Falk RJ, Gharavi AG, Gillespie BW, Gipson DS, Greenbaum LA, Holzman LB, Kretzler M, Robinson B, Smoyer WE, Guay-Woodford LM; CureGN Consortium. Mariani LH, et al. Am J Kidney Dis. 2019 Feb;73(2):218-229. doi: 10.1053/j.ajkd.2018.07.020. Epub 2018 Nov 9. Am J Kidney Dis. 2019. PMID: 30420158 Free PMC article.
Establishing Surrogate Kidney End Points for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes.
Mackay M, Dall'Era M, Fishbein J, Kalunian K, Lesser M, Sanchez-Guerrero J, Levy DM, Silverman E, Petri M, Arriens C, Lewis EJ, Korbet SM, Conti F, Tesar V, Hruskova Z, Borba EF, Bonfa E, Chan TM, Rathi M, Gupta KL, Jha V, Hasni S, West MR, Solomons N, Houssiau FA, Romero-Diaz J, Mejia-Vilet J, Rovin BH. Mackay M, et al. Arthritis Rheumatol. 2019 Mar;71(3):411-419. doi: 10.1002/art.40724. Epub 2019 Feb 1. Arthritis Rheumatol. 2019. PMID: 30225865
B-cell therapy in lupus nephritis: an overview.
Almaani S, Rovin BH. Almaani S, et al. Nephrol Dial Transplant. 2019 Jan 1;34(1):22-29. doi: 10.1093/ndt/gfy267. Nephrol Dial Transplant. 2019. PMID: 30165690 Free PMC article. Review.
Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes.
Looker HC, Merchant ML, Rane MJ, Nelson RG, Kimmel PL, Rovin BH, Klein JB, Mauer M; CKD Biomarkers Consortium. Looker HC, et al. Among authors: rovin bh. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1484-F1492. doi: 10.1152/ajprenal.00183.2018. Epub 2018 Aug 22. Am J Physiol Renal Physiol. 2018. PMID: 30132343 Free PMC article.
Biological Variability of Estimated GFR and Albuminuria in CKD.
Waikar SS, Rebholz CM, Zheng Z, Hurwitz S, Hsu CY, Feldman HI, Xie D, Liu KD, Mifflin TE, Eckfeldt JH, Kimmel PL, Vasan RS, Bonventre JV, Inker LA, Coresh J; Chronic Kidney Disease Biomarkers Consortium Investigators. Waikar SS, et al. Am J Kidney Dis. 2018 Oct;72(4):538-546. doi: 10.1053/j.ajkd.2018.04.023. Epub 2018 Jul 18. Am J Kidney Dis. 2018. PMID: 30031564 Free PMC article.
Lupus community panel proposals for optimising clinical trials: 2018.
Merrill JT, Manzi S, Aranow C, Askanase A, Bruce I, Chakravarty E, Chong B, Costenbader K, Dall'Era M, Ginzler E, Hanrahan L, Kalunian K, Merola J, Raymond S, Rovin B, Saxena A, Werth VP. Merrill JT, et al. Among authors: rovin b. Lupus Sci Med. 2018 Mar 23;5(1):e000258. doi: 10.1136/lupus-2018-000258. eCollection 2018. Lupus Sci Med. 2018. PMID: 29657738 Free PMC article. Review.
412 results