Cawthorne MA - Search Results

1

Dual acting and pan-PPAR activators as potential anti-diabetic therapies.

Heald M, Cawthorne MA. Heald M, et al. Among authors: cawthorne ma. Handb Exp Pharmacol. 2011;(203):35-51. doi: 10.1007/978-3-642-17214-4_2. Handb Exp Pharmacol. 2011. PMID: 21484566 Review.

2

Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation.

Wargent E, Sennitt MV, Stocker C, Mayes AE, Brown L, O'Dowd J, Wang S, Einerhand AW, Mohede I, Arch JR, Cawthorne MA. Wargent E, et al. Among authors: cawthorne ma. Lipids Health Dis. 2005 Jan 10;4:3. doi: 10.1186/1476-511X-4-3. Lipids Health Dis. 2005. PMID: 15642120 Free PMC article.

3

Identification of a novel agonist of peroxisome proliferator-activated receptors alpha and gamma that may contribute to the anti-diabetic activity of guggulipid in Lep(ob)/Lep(ob) mice.

Cornick CL, Strongitharm BH, Sassano G, Rawlins C, Mayes AE, Joseph AN, O'Dowd J, Stocker C, Wargent E, Cawthorne MA, Brown AL, Arch JR. Cornick CL, et al. Among authors: cawthorne ma. J Nutr Biochem. 2009 Oct;20(10):806-15. doi: 10.1016/j.jnutbio.2008.07.010. Epub 2008 Oct 15. J Nutr Biochem. 2009. PMID: 18926687

4

A new, highly selective murine peroxisome proliferator-activated receptor δ agonist increases responsiveness to thermogenic stimuli and glucose uptake in skeletal muscle in obese mice.

Ngala RA, Stocker CJ, Roy AG, Hislop D, Wargent E, Bell R, Hassall DG, Harling JD, Billin AN, Willson TM, Arch JR, Cawthorne MA. Ngala RA, et al. Among authors: cawthorne ma. Diabetes Obes Metab. 2011 May;13(5):455-64. doi: 10.1111/j.1463-1326.2011.01371.x. Epub 2011 Jan 27. Diabetes Obes Metab. 2011. PMID: 21272187

5

Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone.

Wargent E, Stocker C, Augstein P, Heinke P, Meyer A, Hoffmann T, Subramanian A, Sennitt MV, Demuth HU, Arch JR, Cawthorne MA. Wargent E, et al. Among authors: cawthorne ma. Diabetes Obes Metab. 2005 Mar;7(2):170-81. doi: 10.1111/j.1463-1326.2004.00383.x. Diabetes Obes Metab. 2005. PMID: 15715890

6

Beta2-adrenoceptors and non-beta-adrenoceptors mediate effects of BRL37344 and clenbuterol on glucose uptake in soleus muscle: studies using knockout mice.

Ngala RA, O'Dowd J, Wang SJ, Stocker C, Cawthorne MA, Arch JR. Ngala RA, et al. Among authors: cawthorne ma. Br J Pharmacol. 2009 Dec;158(7):1676-82. doi: 10.1111/j.1476-5381.2009.00472.x. Br J Pharmacol. 2009. PMID: 19912225 Free PMC article.

7

Comparison of potential preventive effects of pomegranate flower, peel and seed oil on insulin resistance and inflammation in high-fat and high-sucrose diet-induced obesity mice model.

Harzallah A, Hammami M, Kępczyńska MA, Hislop DC, Arch JR, Cawthorne MA, Zaibi MS. Harzallah A, et al. Among authors: cawthorne ma. Arch Physiol Biochem. 2016;122(2):75-87. doi: 10.3109/13813455.2016.1148053. Epub 2016 Feb 26. Arch Physiol Biochem. 2016. PMID: 26822470

8

Retinoid X receptor agonists have anti-obesity effects and improve insulin sensitivity in Zucker fa/fa rats.

Liu YL, Sennitt MV, Hislop DC, Crombie DL, Heyman RA, Cawthorne MA. Liu YL, et al. Among authors: cawthorne ma. Int J Obes Relat Metab Disord. 2000 Aug;24(8):997-1004. doi: 10.1038/sj.ijo.0801351. Int J Obes Relat Metab Disord. 2000. PMID: 10951538

9

Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and beta2-adrenoceptor mechanisms.

Ngala RA, O'Dowd J, Wang SJ, Agarwal A, Stocker C, Cawthorne MA, Arch JR. Ngala RA, et al. Among authors: cawthorne ma. Br J Pharmacol. 2008 Oct;155(3):395-406. doi: 10.1038/bjp.2008.244. Epub 2008 Jun 16. Br J Pharmacol. 2008. PMID: 18552870 Free PMC article.

10

The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat.

Emilsson V, O'Dowd J, Wang S, Liu YL, Sennitt M, Heyman R, Cawthorne MA. Emilsson V, et al. Among authors: cawthorne ma. Metabolism. 2000 Dec;49(12):1610-5. doi: 10.1053/meta.2000.18692. Metabolism. 2000. PMID: 11145125

11

Opportunities and challenges for the development of pharmacological therapies for obesity treatment.

Cawthorne MA. Cawthorne MA. Obes Rev. 2007 Mar;8 Suppl 1:131-6. doi: 10.1111/j.1467-789X.2007.00332.x. Obes Rev. 2007. PMID: 17316316 Review. No abstract available.

12

Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases.

Christiansen E, Watterson KR, Stocker CJ, Sokol E, Jenkins L, Simon K, Grundmann M, Petersen RK, Wargent ET, Hudson BD, Kostenis E, Ejsing CS, Cawthorne MA, Milligan G, Ulven T. Christiansen E, et al. Among authors: cawthorne ma. Br J Nutr. 2015 Jun 14;113(11):1677-88. doi: 10.1017/S000711451500118X. Epub 2015 Apr 28. Br J Nutr. 2015. PMID: 25916176 Free article.

13

Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy.

Hansen SV, Christiansen E, Urban C, Hudson BD, Stocker CJ, Due-Hansen ME, Wargent ET, Shimpukade B, Almeida R, Ejsing CS, Cawthorne MA, Kassack MU, Milligan G, Ulven T. Hansen SV, et al. Among authors: cawthorne ma. J Med Chem. 2016 Mar 24;59(6):2841-6. doi: 10.1021/acs.jmedchem.5b01962. Epub 2016 Mar 15. J Med Chem. 2016. PMID: 26928019

14

The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity.

Wargent ET, Zaibi MS, Silvestri C, Hislop DC, Stocker CJ, Stott CG, Guy GW, Duncan M, Di Marzo V, Cawthorne MA. Wargent ET, et al. Among authors: cawthorne ma. Nutr Diabetes. 2013 May 27;3(5):e68. doi: 10.1038/nutd.2013.9. Nutr Diabetes. 2013. PMID: 23712280 Free PMC article.

15

Stimulation of glucose uptake in murine soleus muscle and adipocytes by 5-(4-phenoxybutoxy)psoralen (PAP-1) may be mediated by Kv1.5 rather than Kv1.3.

Ngala RA, Zaibi MS, Langlands K, Stocker CJ, Arch JR, Cawthorne MA. Ngala RA, et al. Among authors: cawthorne ma. PeerJ. 2014 Oct 7;2:e614. doi: 10.7717/peerj.614. eCollection 2014. PeerJ. 2014. PMID: 25320682 Free PMC article.

16

Leptin signalling in pancreatic islets and clonal insulin-secreting cells.

Morton NM, Emilsson V, de Groot P, Pallett AL, Cawthorne MA. Morton NM, et al. Among authors: cawthorne ma. J Mol Endocrinol. 1999 Apr;22(2):173-84. doi: 10.1677/jme.0.0220173. J Mol Endocrinol. 1999. PMID: 10194520

17

BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro.

Board M, Doyle P, Cawthorne MA. Board M, et al. Among authors: cawthorne ma. Eur J Pharmacol. 2000 Oct 6;406(1):33-40. doi: 10.1016/s0014-2999(00)00671-3. Eur J Pharmacol. 2000. PMID: 11011029

18

Prevention of diet-induced obesity and impaired glucose tolerance in rats following administration of leptin to their mothers.

Stocker CJ, Wargent E, O'Dowd J, Cornick C, Speakman JR, Arch JR, Cawthorne MA. Stocker CJ, et al. Among authors: cawthorne ma. Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1810-8. doi: 10.1152/ajpregu.00676.2006. Epub 2007 Jan 18. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17234956 Free article.

19

Interleukin-1beta activates a short STAT-3 isoform in clonal insulin-secreting cells.

Morton NM, de Groot RP, Cawthorne MA, Emilsson V. Morton NM, et al. Among authors: cawthorne ma. FEBS Lett. 1999 Jan 8;442(1):57-60. doi: 10.1016/s0014-5793(98)01623-8. FEBS Lett. 1999. PMID: 9923604 Free article.

20

Hexosamines and nutrient excess induce leptin production and leptin receptor activation in pancreatic islets and clonal beta-cells.

Emilsson V, O'Dowd J, Nolan AL, Cawthorne MA. Emilsson V, et al. Among authors: cawthorne ma. Endocrinology. 2001 Oct;142(10):4414-9. doi: 10.1210/endo.142.10.8414. Endocrinology. 2001. PMID: 11564705

21

Modulation of susceptibility to weight gain and insulin resistance in low birthweight rats by treatment of their mothers with leptin during pregnancy and lactation.

Stocker C, O'Dowd J, Morton NM, Wargent E, Sennitt MV, Hislop D, Glund S, Seckl JR, Arch JR, Cawthorne MA. Stocker C, et al. Among authors: cawthorne ma. Int J Obes Relat Metab Disord. 2004 Jan;28(1):129-36. doi: 10.1038/sj.ijo.0802476. Int J Obes Relat Metab Disord. 2004. PMID: 14557827

22

Circulating levels of the cytokines IL10, IFNγ and resistin in an obese mouse model of developmental programming.

Kępczyńska MA, Wargent ET, Cawthorne MA, Arch JR, O'Dowd JF, Stocker CJ. Kępczyńska MA, et al. Among authors: cawthorne ma. J Dev Orig Health Dis. 2013 Dec;4(6):491-8. doi: 10.1017/S2040174413000263. J Dev Orig Health Dis. 2013. PMID: 24924228

23

The thiazolidinedione insulin sensitiser, BRL 49653, increases the expression of PPAR-gamma and aP2 in adipose tissue of high-fat-fed rats.

Pearson SL, Cawthorne MA, Clapham JC, Dunmore SJ, Holmes SD, Moore GB, Smith SA, Tadayyon M. Pearson SL, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1996 Dec 24;229(3):752-7. doi: 10.1006/bbrc.1996.1876. Biochem Biophys Res Commun. 1996. PMID: 8954968

24

Improved glucose tolerance in acyl CoA:diacylglycerol acyltransferase 1-null mice is dependent on diet.

Wang SJ, Cornick C, O'Dowd J, Cawthorne MA, Arch JR. Wang SJ, et al. Among authors: cawthorne ma. Lipids Health Dis. 2007 Jan 19;6:2. doi: 10.1186/1476-511X-6-2. Lipids Health Dis. 2007. PMID: 17239230 Free PMC article.

25

Enhanced diabetogenic effect of streptozotocin in mice overexpressing UCP-3 in skeletal muscle.

Wang S, Cawthorne MA, Clapham JC. Wang S, et al. Among authors: cawthorne ma. Ann N Y Acad Sci. 2002 Jun;967:112-9. doi: 10.1111/j.1749-6632.2002.tb04269.x. Ann N Y Acad Sci. 2002. PMID: 12079841

26

Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes.

Wargent ET, Zaibi MS, O'Dowd JF, Cawthorne MA, Wang SJ, Arch JR, Stocker CJ. Wargent ET, et al. Among authors: cawthorne ma. PeerJ. 2015 Feb 5;3:e753. doi: 10.7717/peerj.753. eCollection 2015. PeerJ. 2015. PMID: 25699203 Free PMC article.

27

Contrasts between the effects of zinc-α2-glycoprotein, a putative β3/2-adrenoceptor agonist and the β3/2-adrenoceptor agonist BRL35135 in C57Bl/6 (ob/ob) mice.

Wargent ET, O'Dowd JF, Zaibi MS, Gao D, Bing C, Trayhurn P, Cawthorne MA, Arch JR, Stocker CJ. Wargent ET, et al. Among authors: cawthorne ma. J Endocrinol. 2013 Jan 18;216(2):157-68. doi: 10.1530/JOE-12-0402. Print 2013 Feb. J Endocrinol. 2013. PMID: 23151357

28

The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity.

Butler J, Smyth N, Broadbridge R, Council CE, Lee AG, Stocker CJ, Hislop DC, Arch JR, Cawthorne MA, Malcolm East J. Butler J, et al. Among authors: cawthorne ma. Arch Biochem Biophys. 2015 Mar 1;569:26-31. doi: 10.1016/j.abb.2015.01.027. Epub 2015 Feb 7. Arch Biochem Biophys. 2015. PMID: 25660043 Free PMC article.

29

American Diabetes Association--61st scientific sessions. GLP-1, exendin and PPAR modulators.

Cawthorne M. Cawthorne M. IDrugs. 2001 Sep;4(9):978-82. IDrugs. 2001. PMID: 15965835 No abstract available.

30

Fetal origins of insulin resistance and obesity.

Stocker CJ, Arch JR, Cawthorne MA. Stocker CJ, et al. Among authors: cawthorne ma. Proc Nutr Soc. 2005 May;64(2):143-51. doi: 10.1079/pns2005417. Proc Nutr Soc. 2005. PMID: 15960859 Review.

31

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

Bellahcene M, O'Dowd JF, Wargent ET, Zaibi MS, Hislop DC, Ngala RA, Smith DM, Cawthorne MA, Stocker CJ, Arch JR. Bellahcene M, et al. Among authors: cawthorne ma. Br J Nutr. 2013 May 28;109(10):1755-64. doi: 10.1017/S0007114512003923. Epub 2012 Oct 31. Br J Nutr. 2013. PMID: 23110765

32

A novel method to assess collagen architecture in skin.

Osman OS, Selway JL, Harikumar PE, Stocker CJ, Wargent ET, Cawthorne MA, Jassim S, Langlands K. Osman OS, et al. Among authors: cawthorne ma. BMC Bioinformatics. 2013 Aug 26;14:260. doi: 10.1186/1471-2105-14-260. BMC Bioinformatics. 2013. PMID: 23971965 Free PMC article.

33

Leptin inhibits insulin secretion and reduces insulin mRNA levels in rat isolated pancreatic islets.

Pallett AL, Morton NM, Cawthorne MA, Emilsson V. Pallett AL, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1997 Sep 8;238(1):267-70. doi: 10.1006/bbrc.1997.7274. Biochem Biophys Res Commun. 1997. PMID: 9299491

34

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.

Zaibi MS, Stocker CJ, O'Dowd J, Davies A, Bellahcene M, Cawthorne MA, Brown AJ, Smith DM, Arch JR. Zaibi MS, et al. Among authors: cawthorne ma. FEBS Lett. 2010 Jun 3;584(11):2381-6. doi: 10.1016/j.febslet.2010.04.027. Epub 2010 Apr 20. FEBS Lett. 2010. PMID: 20399779 Free article.

35

Beta-cell tropin- and glucose-induced hypersecretion of insulin and amylin from perfused fatty rat pancreas.

Dunmore SJ, Cawthorne MA, Hislop DC, Morton JL, Beloff-Chain A. Dunmore SJ, et al. Among authors: cawthorne ma. J Endocrinol. 1993 Jun;137(3):375-81. doi: 10.1677/joe.0.1370375. J Endocrinol. 1993. PMID: 8396617

36

Increased fatty acid oxidation in transgenic mice overexpressing UCP3 in skeletal muscle.

Wang S, Subramaniam A, Cawthorne MA, Clapham JC. Wang S, et al. Among authors: cawthorne ma. Diabetes Obes Metab. 2003 Sep;5(5):295-301. doi: 10.1046/j.1463-1326.2003.00273.x. Diabetes Obes Metab. 2003. PMID: 12940866

37

Leptin inhibits glycogen synthesis in the isolated soleus muscle of obese (ob/ob) mice.

Liu YL, Emilsson V, Cawthorne MA. Liu YL, et al. Among authors: cawthorne ma. FEBS Lett. 1997 Jul 14;411(2-3):351-5. doi: 10.1016/s0014-5793(97)00732-1. FEBS Lett. 1997. PMID: 9271234 Free article.

38

Leanness in postnatally nutritionally programmed rats is associated with increased sensitivity to leptin and a melanocortin receptor agonist and decreased sensitivity to neuropeptide Y.

Stocker CJ, Wargent ET, Martin-Gronert MS, Cripps RL, O'Dowd JF, Zaibi MS, Cottrell EC, Mercer JG, Duncan JS, Cawthorne MA, Ozanne SE, Arch JR. Stocker CJ, et al. Among authors: cawthorne ma. Int J Obes (Lond). 2012 Aug;36(8):1040-6. doi: 10.1038/ijo.2011.226. Epub 2011 Nov 29. Int J Obes (Lond). 2012. PMID: 22124449 Free PMC article.

39

A novel automated image analysis method for accurate adipocyte quantification.

Osman OS, Selway JL, Kępczyńska MA, Stocker CJ, O'Dowd JF, Cawthorne MA, Arch JR, Jassim S, Langlands K. Osman OS, et al. Among authors: cawthorne ma. Adipocyte. 2013 Jul 1;2(3):160-4. doi: 10.4161/adip.24652. Epub 2013 Apr 16. Adipocyte. 2013. PMID: 23991362 Free PMC article.

40

The influence of leptin on early life programming of obesity.

Stocker CJ, Cawthorne MA. Stocker CJ, et al. Among authors: cawthorne ma. Trends Biotechnol. 2008 Oct;26(10):545-51. doi: 10.1016/j.tibtech.2008.06.004. Epub 2008 Aug 14. Trends Biotechnol. 2008. PMID: 18706724

41

5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats.

Martin-Gronert MS, Stocker CJ, Wargent ET, Cripps RL, Garfield AS, Jovanovic Z, D'Agostino G, Yeo GS, Cawthorne MA, Arch JR, Heisler LK, Ozanne SE. Martin-Gronert MS, et al. Among authors: cawthorne ma. Dis Model Mech. 2016 Apr;9(4):401-12. doi: 10.1242/dmm.023903. Epub 2016 Jan 14. Dis Model Mech. 2016. PMID: 26769798 Free PMC article.

42

Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice.

Sanchez JC, Converset V, Nolan A, Schmid G, Wang S, Heller M, Sennitt MV, Hochstrasser DF, Cawthorne MA. Sanchez JC, et al. Among authors: cawthorne ma. Proteomics. 2003 Aug;3(8):1500-20. doi: 10.1002/pmic.200300484. Proteomics. 2003. PMID: 12923776

43

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.

Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martínez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Tóth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H. Yavari A, et al. Among authors: cawthorne ma. Cell Metab. 2016 May 10;23(5):821-36. doi: 10.1016/j.cmet.2016.04.003. Epub 2016 Apr 28. Cell Metab. 2016. PMID: 27133129 Free PMC article.

44

BRL 35135, a potent and selective atypical beta-adrenoceptor agonist.

Cawthorne MA, Sennitt MV, Arch JR, Smith SA. Cawthorne MA, et al. Am J Clin Nutr. 1992 Jan;55(1 Suppl):252S-257S. doi: 10.1093/ajcn/55.1.252s. Am J Clin Nutr. 1992. PMID: 1345889 Review.

45

Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues.

Emilsson V, Arch JR, de Groot RP, Lister CA, Cawthorne MA. Emilsson V, et al. Among authors: cawthorne ma. FEBS Lett. 1999 Jul 16;455(1-2):170-4. doi: 10.1016/s0014-5793(99)00874-1. FEBS Lett. 1999. PMID: 10428495 Free article.

46

β2-adrenoceptor agonists can both stimulate and inhibit glucose uptake in mouse soleus muscle through ligand-directed signalling.

Ngala RA, O'Dowd JF, Stocker CJ, Cawthorne MA, Arch JR. Ngala RA, et al. Among authors: cawthorne ma. Naunyn Schmiedebergs Arch Pharmacol. 2013 Sep;386(9):761-73. doi: 10.1007/s00210-013-0860-5. Epub 2013 Apr 6. Naunyn Schmiedebergs Arch Pharmacol. 2013. PMID: 23564017

47

Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice.

Haynes AC, Chapman H, Taylor C, Moore GB, Cawthorne MA, Tadayyon M, Clapham JC, Arch JR. Haynes AC, et al. Among authors: cawthorne ma. Regul Pept. 2002 Mar 15;104(1-3):153-9. doi: 10.1016/s0167-0115(01)00358-5. Regul Pept. 2002. PMID: 11830290

48

Effect of rosiglitazone on the differential expression of diabetes-associated proteins in pancreatic islets of C57Bl/6 lep/lep mice.

Sanchez JC, Converset V, Nolan A, Schmid G, Wang S, Heller M, Sennitt MV, Hochstrasser DF, Cawthorne MA. Sanchez JC, et al. Among authors: cawthorne ma. Mol Cell Proteomics. 2002 Jul;1(7):509-16. doi: 10.1074/mcp.m200033-mcp200. Mol Cell Proteomics. 2002. PMID: 12239279 Free article.

49

Inhibition of insulin secretion by betagranin, an N-terminal chromogranin A fragment.

Schmid GM, Meda P, Caille D, Wargent E, O'Dowd J, Hochstrasser DF, Cawthorne MA, Sanchez JC. Schmid GM, et al. Among authors: cawthorne ma. J Biol Chem. 2007 Apr 27;282(17):12717-24. doi: 10.1074/jbc.M700788200. Epub 2007 Feb 8. J Biol Chem. 2007. PMID: 17289672 Free article.

50

Anti-hyperglycaemic action of BRL 26830, a novel beta-adrenoceptor agonist, in mice and rats.

Sennitt MV, Arch JR, Levy AL, Simson DL, Smith SA, Cawthorne MA. Sennitt MV, et al. Among authors: cawthorne ma. Biochem Pharmacol. 1985 Apr 15;34(8):1279-85. doi: 10.1016/0006-2952(85)90506-4. Biochem Pharmacol. 1985. PMID: 2859857

51

Effects of BRL 26830, a novel beta-adrenoceptor agonist, on glucose tolerance, insulin sensitivity and glucose turnover in Zucker (fa/fa) rats.

Smith SA, Levy AL, Sennitt MV, Simson DL, Cawthorne MA. Smith SA, et al. Among authors: cawthorne ma. Biochem Pharmacol. 1985 Jul 15;34(14):2425-9. doi: 10.1016/0006-2952(85)90521-0. Biochem Pharmacol. 1985. PMID: 2861816

52

Effects of novel beta-adrenoceptor agonists on carbohydrate metabolism: relevance for the treatment of non-insulin-dependent diabetes.

Cawthorne MA, Carroll MJ, Levy AL, Lister CA, Sennitt MV, Smith SA, Young P. Cawthorne MA, et al. Int J Obes. 1984;8 Suppl 1:93-102. Int J Obes. 1984. PMID: 6152558

53

Improved glycemic control in C57Bl/KsJ (db/db) mice after treatment with the thermogenic beta-adrenoceptor agonist, BRL 26830.

Carroll MJ, Lister CA, Sennitt MV, Stewart-Long N, Cawthorne MA. Carroll MJ, et al. Among authors: cawthorne ma. Diabetes. 1985 Nov;34(11):1198-204. doi: 10.2337/diab.34.11.1198. Diabetes. 1985. PMID: 2864298

54

Effect of a novel thermogenic beta-adrenoceptor agonist (BRL 26830) on insulin resistance in soleus muscle from obese Zucker rats.

Challiss RA, Budohoski L, Newsholme EA, Sennitt MV, Cawthorne MA. Challiss RA, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1985 Apr 30;128(2):928-35. doi: 10.1016/0006-291x(85)90135-4. Biochem Biophys Res Commun. 1985. PMID: 2986630

55

Effects of nafenopin, diphenylhydantoin, phenobarbitone and some acetylenes on body composition: is there a relationship between decreased carcass lipid and increased liver size and induction of drug metabolizing enzymes?

Arch JR, Green A, Cawthorne MA. Arch JR, et al. Among authors: cawthorne ma. Int J Obes. 1980;4(1):1-10. Int J Obes. 1980. PMID: 7390696

56

Effect of high-fat diet on the expression of proteins in muscle, adipose tissues, and liver of C57BL/6 mice.

Schmid GM, Converset V, Walter N, Sennitt MV, Leung KY, Byers H, Ward M, Hochstrasser DF, Cawthorne MA, Sanchez JC. Schmid GM, et al. Among authors: cawthorne ma. Proteomics. 2004 Aug;4(8):2270-82. doi: 10.1002/pmic.200300810. Proteomics. 2004. PMID: 15274121

57

Effects of acetylenedicarboxylate: relationship between decreased carcass lipid and increased liver size and lean body weight.

Arch JR, Cornish S, Green A, Cawthorne MA. Arch JR, et al. Among authors: cawthorne ma. Int J Obes. 1979;3(4):289-99. Int J Obes. 1979. PMID: 393646

58

SK&F 104078, a post-junctionally selective alpha 2-adrenoceptor antagonist in the human saphenous vein in vitro.

Roberts SP, Kelly J, Cawthorne MA, Sennitt MV. Roberts SP, et al. Among authors: cawthorne ma. Naunyn Schmiedebergs Arch Pharmacol. 1992 Mar;345(3):327-32. doi: 10.1007/BF00168694. Naunyn Schmiedebergs Arch Pharmacol. 1992. PMID: 1352382

59

The search for peripherally acting drugs for the treatment of obesity - a review.

Cawthorne MA, Arch JR. Cawthorne MA, et al. Int J Obes. 1982;6(1):1-10. Int J Obes. 1982. PMID: 7040264 Review.

60

Thermogenic and anorectic effects of ephedrine and congeners in mice and rats.

Arch JR, Ainsworth AT, Cawthorne MA. Arch JR, et al. Among authors: cawthorne ma. Life Sci. 1982 May 24;30(21):1817-26. doi: 10.1016/0024-3205(82)90319-8. Life Sci. 1982. PMID: 7098772

61

The contribution of classical (beta1/2-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta3-adrenoceptor agonists of differing selectivities.

Sennitt MV, Kaumann AJ, Molenaar P, Beeley LJ, Young PW, Kelly J, Chapman H, Henson SM, Berge JM, Dean DK, Kotecha NR, Morgan HK, Rami HK, Ward RW, Thompson M, Wilson S, Smith SA, Cawthorne MA, Stock MJ, Arch JR. Sennitt MV, et al. Among authors: cawthorne ma. J Pharmacol Exp Ther. 1998 Jun;285(3):1084-95. J Pharmacol Exp Ther. 1998. PMID: 9618411

62

A simple apparatus for comparative measurements of energy expenditure in human subjects: the thermic effect of caffeine.

Hollands MA, Arch JR, Cawthorne MA. Hollands MA, et al. Among authors: cawthorne ma. Am J Clin Nutr. 1981 Oct;34(10):2291-4. doi: 10.1093/ajcn/34.10.2291. Am J Clin Nutr. 1981. PMID: 7293955 Clinical Trial.

63

Atypical beta-adrenoceptor on brown adipocytes as target for anti-obesity drugs.

Arch JR, Ainsworth AT, Cawthorne MA, Piercy V, Sennitt MV, Thody VE, Wilson C, Wilson S. Arch JR, et al. Among authors: cawthorne ma. Nature. 1984 May 10-16;309(5964):163-5. doi: 10.1038/309163a0. Nature. 1984. PMID: 6325935

64

Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet.

Stolarczyk E, Vong CT, Perucha E, Jackson I, Cawthorne MA, Wargent ET, Powell N, Canavan JB, Lord GM, Howard JK. Stolarczyk E, et al. Among authors: cawthorne ma. Cell Metab. 2013 Apr 2;17(4):520-33. doi: 10.1016/j.cmet.2013.02.019. Cell Metab. 2013. PMID: 23562076 Free PMC article.

65

The beta-adrenoceptor selectivity profile of BRL 37344 in the pithed rat.

Oriowo MA, Sennitt MV, Smith SA, Ruffolo RR Jr, Cawthorne MA. Oriowo MA, et al. Among authors: cawthorne ma. J Auton Pharmacol. 1994 Oct;14(5):337-44. doi: 10.1111/j.1474-8673.1994.tb00614.x. J Auton Pharmacol. 1994. PMID: 7829538

66

Peripheral metabolic actions of leptin.

Cawthorne MA, Morton NM, Pallett AL, Liu YL, Emilsson V. Cawthorne MA, et al. Proc Nutr Soc. 1998 Aug;57(3):449-53. doi: 10.1079/pns19980064. Proc Nutr Soc. 1998. PMID: 9794003 Review. No abstract available.

67

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion.

Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M. Emilsson V, et al. Among authors: cawthorne ma. Diabetes. 1997 Feb;46(2):313-6. doi: 10.2337/diab.46.2.313. Diabetes. 1997. PMID: 9000710

68

Biphasic effects of the beta-adrenoceptor agonist, BRL 37344, on glucose utilization in rat isolated skeletal muscle.

Liu YL, Cawthorne MA, Stock MJ. Liu YL, et al. Among authors: cawthorne ma. Br J Pharmacol. 1996 Mar;117(6):1355-61. doi: 10.1111/j.1476-5381.1996.tb16736.x. Br J Pharmacol. 1996. PMID: 8882636 Free PMC article.

69

The selectivity in vitro of the stereoisomers of the beta-3 adrenoceptor agonist BRL 37344.

Oriowo MA, Chapman H, Kirkham DM, Sennitt MV, Ruffolo RR Jr, Cawthorne MA. Oriowo MA, et al. Among authors: cawthorne ma. J Pharmacol Exp Ther. 1996 Apr;277(1):22-7. J Pharmacol Exp Ther. 1996. PMID: 8613923

70

Vitamin E and hepatotoxic agents. 3. Vitamin E, synthetic antioxidants and carbon tetrachloride toxicity in the rat.

Cawthorne MA, Bunyan J, Sennitt MV, Green J, Grasso P. Cawthorne MA, et al. Br J Nutr. 1970 Jun;24(2):357-84. doi: 10.1079/bjn19700038. Br J Nutr. 1970. PMID: 5452694 No abstract available.

71

Respective degree of expression of beta 1-, beta 2- and beta 3-adrenoceptors in human brown and white adipose tissues.

Deng C, Paoloni-Giacobino A, Kuehne F, Boss O, Revelli JP, Moinat M, Cawthorne MA, Muzzin P, Giacobino JP. Deng C, et al. Among authors: cawthorne ma. Br J Pharmacol. 1996 Jun;118(4):929-34. doi: 10.1111/j.1476-5381.1996.tb15488.x. Br J Pharmacol. 1996. PMID: 8799564 Free PMC article.

72

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes.

Christiansen E, Hansen SV, Urban C, Hudson BD, Wargent ET, Grundmann M, Jenkins L, Zaibi M, Stocker CJ, Ullrich S, Kostenis E, Kassack MU, Milligan G, Cawthorne MA, Ulven T. Christiansen E, et al. Among authors: cawthorne ma. ACS Med Chem Lett. 2013 May 9;4(5):441-445. doi: 10.1021/ml4000673. Epub 2013 Apr 8. ACS Med Chem Lett. 2013. PMID: 23687558 Free PMC article.

73

Effects of BRL 35135, a beta-adrenoceptor agonist with novel selectivity, on glucose tolerance and insulin sensitivity in obese subjects.

Mitchell TH, Ellis RD, Smith SA, Robb G, Cawthorne MA. Mitchell TH, et al. Among authors: cawthorne ma. Int J Obes. 1989;13(6):757-66. Int J Obes. 1989. PMID: 2695481

74

The tissue distribution of the human beta3-adrenoceptor studied using a monoclonal antibody: direct evidence of the beta3-adrenoceptor in human adipose tissue, atrium and skeletal muscle.

Chamberlain PD, Jennings KH, Paul F, Cordell J, Berry A, Holmes SD, Park J, Chambers J, Sennitt MV, Stock MJ, Cawthorne MA, Young PW, Murphy GJ. Chamberlain PD, et al. Among authors: cawthorne ma. Int J Obes Relat Metab Disord. 1999 Oct;23(10):1057-65. doi: 10.1038/sj.ijo.0801039. Int J Obes Relat Metab Disord. 1999. PMID: 10557026

75

Free fatty acid receptor 1 (FFA1/GPR40) agonists: mesylpropoxy appendage lowers lipophilicity and improves ADME properties.

Christiansen E, Due-Hansen ME, Urban C, Grundmann M, Schröder R, Hudson BD, Milligan G, Cawthorne MA, Kostenis E, Kassack MU, Ulven T. Christiansen E, et al. Among authors: cawthorne ma. J Med Chem. 2012 Jul 26;55(14):6624-8. doi: 10.1021/jm3002026. Epub 2012 Jul 13. J Med Chem. 2012. PMID: 22724451

76

Discovery of a potent and selective free fatty acid receptor 1 agonist with low lipophilicity and high oral bioavailability.

Christiansen E, Due-Hansen ME, Urban C, Grundmann M, Schmidt J, Hansen SV, Hudson BD, Zaibi M, Markussen SB, Hagesaether E, Milligan G, Cawthorne MA, Kostenis E, Kassack MU, Ulven T. Christiansen E, et al. Among authors: cawthorne ma. J Med Chem. 2013 Feb 14;56(3):982-92. doi: 10.1021/jm301470a. Epub 2013 Jan 22. J Med Chem. 2013. PMID: 23294321

77

A MATLAB tool for pathway enrichment using a topology-based pathway regulation score.

Ibrahim M, Jassim S, Cawthorne MA, Langlands K. Ibrahim M, et al. Among authors: cawthorne ma. BMC Bioinformatics. 2014 Nov 4;15(1):358. doi: 10.1186/s12859-014-0358-2. BMC Bioinformatics. 2014. PMID: 25367050 Free PMC article.

78

A topology-based score for pathway enrichment.

Ibrahim MA, Jassim S, Cawthorne MA, Langlands K. Ibrahim MA, et al. Among authors: cawthorne ma. J Comput Biol. 2012 May;19(5):563-73. doi: 10.1089/cmb.2011.0182. Epub 2012 Apr 2. J Comput Biol. 2012. PMID: 22468678

79

Leptin action in intestinal cells.

Morton NM, Emilsson V, Liu YL, Cawthorne MA. Morton NM, et al. Among authors: cawthorne ma. J Biol Chem. 1998 Oct 2;273(40):26194-201. doi: 10.1074/jbc.273.40.26194. J Biol Chem. 1998. PMID: 9748302 Free article.

80

Muscles of diabetic (db/db) mice: fibre size, fibre type and the effects of a thermogenic, beta-adrenoceptor agonist.

Almond RE, Cawthorne MA, Enser M. Almond RE, et al. Among authors: cawthorne ma. Int J Obes. 1988;12(1):81-91. Int J Obes. 1988. PMID: 2896180

81

Chemerin, a novel adipokine in the regulation of angiogenesis.

Bozaoglu K, Curran JE, Stocker CJ, Zaibi MS, Segal D, Konstantopoulos N, Morrison S, Carless M, Dyer TD, Cole SA, Goring HH, Moses EK, Walder K, Cawthorne MA, Blangero J, Jowett JB. Bozaoglu K, et al. Among authors: cawthorne ma. J Clin Endocrinol Metab. 2010 May;95(5):2476-85. doi: 10.1210/jc.2010-0042. Epub 2010 Mar 17. J Clin Endocrinol Metab. 2010. PMID: 20237162 Free PMC article.

82

Brown adipose tissue is a major site of glucose utilisation in C57Bl/6 ob/ob mice treated with a thermogenic beta-adrenoceptor agonist.

Young P, Cawthorne MA, Smith SA. Young P, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1985 Jul 16;130(1):241-8. doi: 10.1016/0006-291x(85)90408-5. Biochem Biophys Res Commun. 1985. PMID: 4026829

83

Lipogenesis in vivo in lean and genetically obese (ob/ob) mice fed on diets with a high fat content.

Cawthorne MA, Cornish S. Cawthorne MA, et al. Int J Obes. 1979;3(1):83-90. Int J Obes. 1979. PMID: 528121

84

Quantification in vivo of the effects of insulin on glucose utilization in individual tissues of warm- and cold-acclimated rats.

Smith SA, Young P, Cawthorne MA. Smith SA, et al. Among authors: cawthorne ma. Biochem J. 1986 Aug 1;237(3):789-95. doi: 10.1042/bj2370789. Biochem J. 1986. PMID: 3541903 Free PMC article.

85

Defective activation by glucose of hepatic glycogen synthesis in the obese hyperglycaemic mouse.

Smith SA, Cawthorne MA, Levy AL, Simson DL. Smith SA, et al. Among authors: cawthorne ma. Biochem J. 1983 Nov 15;216(2):491-4. doi: 10.1042/bj2160491. Biochem J. 1983. PMID: 6419733 Free PMC article.

86

Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling.

Young PW, Cawthorne MA, Coyle PJ, Holder JC, Holman GD, Kozka IJ, Kirkham DM, Lister CA, Smith SA. Young PW, et al. Among authors: cawthorne ma. Diabetes. 1995 Sep;44(9):1087-92. doi: 10.2337/diab.44.9.1087. Diabetes. 1995. PMID: 7657033

87

Glucose metabolism in the obese hyperglycaemic (C57B1/6 ob/ob) mouse: the effects of fasting on glucose turnover rates.

Smith SA, Cawthorne MA, Simson DL. Smith SA, et al. Among authors: cawthorne ma. Diabetes Res. 1986 Feb;3(2):83-6. Diabetes Res. 1986. PMID: 3698484

88

The effects of the beta3-adrenoceptor agonist BRL 35135 on UCP isoform mRNA expression.

Emilsson V, Summers RJ, Hamilton S, Liu YL, Cawthorne MA. Emilsson V, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1998 Nov 18;252(2):450-4. doi: 10.1006/bbrc.1998.9667. Biochem Biophys Res Commun. 1998. PMID: 9826550

89

[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents.

Cantello BC, Cawthorne MA, Cottam GP, Duff PT, Haigh D, Hindley RM, Lister CA, Smith SA, Thurlby PL. Cantello BC, et al. Among authors: cawthorne ma. J Med Chem. 1994 Nov 11;37(23):3977-85. doi: 10.1021/jm00049a017. J Med Chem. 1994. PMID: 7966158

90

The effects of insulin and the pituitary peptide beta-cell tropin on the incorporation of D-3-3H-glucose into lipid in brown adipocytes from lactating and non-lactating rats.

Davenport M, Morton JL, Beloff-Chain A, Dunmore SJ, Cawthorne MA. Davenport M, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1437-41. doi: 10.1016/0006-291x(91)92100-x. Biochem Biophys Res Commun. 1991. PMID: 1662498

91

Two non-psychoactive cannabinoids reduce intracellular lipid levels and inhibit hepatosteatosis.

Silvestri C, Paris D, Martella A, Melck D, Guadagnino I, Cawthorne M, Motta A, Di Marzo V. Silvestri C, et al. J Hepatol. 2015 Jun;62(6):1382-90. doi: 10.1016/j.jhep.2015.01.001. Epub 2015 Jan 13. J Hepatol. 2015. PMID: 25595882

92

Changes in plasma beta-cell tropin concentrations during pregnancy in rats.

Davenport M, Morton JL, Cawthorne MA. Davenport M, et al. Among authors: cawthorne ma. J Endocrinol. 1995 Jul;146(1):177-82. doi: 10.1677/joe.0.1460177. J Endocrinol. 1995. PMID: 7561615

93

Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells.

Ibrahimi A, Teboul L, Gaillard D, Amri EZ, Ailhaud G, Young P, Cawthorne MA, Grimaldi PA. Ibrahimi A, et al. Among authors: cawthorne ma. Mol Pharmacol. 1994 Dec;46(6):1070-6. Mol Pharmacol. 1994. PMID: 7808426

94

Correlation of beta 3-adrenoceptor-induced activation of cyclic AMP-dependent protein kinase with activation of lipolysis in rat white adipocytes.

Murphy GJ, Kirkham DM, Cawthorne MA, Young P. Murphy GJ, et al. Among authors: cawthorne ma. Biochem Pharmacol. 1993 Aug 17;46(4):575-81. doi: 10.1016/0006-2952(93)90540-d. Biochem Pharmacol. 1993. PMID: 8103324

95

Control of beta 3-adrenergic receptor gene expression in brown adipocytes in culture.

Klaus S, Muzzin P, Revelli JP, Cawthorne MA, Giacobino JP, Ricquier D. Klaus S, et al. Among authors: cawthorne ma. Mol Cell Endocrinol. 1995 Apr 1;109(2):189-95. doi: 10.1016/0303-7207(95)03502-x. Mol Cell Endocrinol. 1995. PMID: 7664982

96

ADA - 60th Scientific Sessions. Late-breaking research abstracts.

Cawthorne M. Cawthorne M. IDrugs. 2000 Sep;3(9):1004-5. IDrugs. 2000. PMID: 16049852 No abstract available.

97

Obesity: non-insulin dependent diabetes mellitus.

Cawthorne M. Cawthorne M. IDrugs. 2000 Aug;3(8):887-9. IDrugs. 2000. PMID: 16059803 No abstract available.

98

Evaluation of inhibitory guanine nucleotide regulatory protein Gi function in hepatocyte and liver membranes from obese Zucker (fa/fa) rats and their lean (Fa/?) littermates.

Young P, Kirkham DM, Murphy GJ, Cawthorne MA. Young P, et al. Among authors: cawthorne ma. Diabetologia. 1991 Aug;34(8):565-9. doi: 10.1007/BF00400274. Diabetologia. 1991. PMID: 1936659

99

Identification of beta-cell-trophin, a peptide of the pituitary pars intermedia which stimulates insulin secretion in plasma from genetically obese (ob/ob) mice.

Billingham N, Beloff-Chain A, Cawthorne MA. Billingham N, et al. Among authors: cawthorne ma. J Endocrinol. 1982 Jul;94(1):125-30. doi: 10.1677/joe.0.0940125. J Endocrinol. 1982. PMID: 7047665

100

Acute regulation of insulin release by the pituitary gland in relation to hyperinsulinaemia and obesity.

Beloff-Chain A, Bogdanovic S, Cawthorne MA. Beloff-Chain A, et al. Among authors: cawthorne ma. J Endocrinol. 1979 Jun;81(3):271-9. doi: 10.1677/joe.0.0810271. J Endocrinol. 1979. PMID: 381564

101

Influence of fasting on basal and pituitary-stimulated insulin secretion from perifused pancreatic islets of lean and obese mice.

Beloff-Chain A, Bogdanovic S, Cawthorne MA. Beloff-Chain A, et al. Among authors: cawthorne ma. FEBS Lett. 1977 Apr 15;76(2):290-3. doi: 10.1016/0014-5793(77)80170-1. FEBS Lett. 1977. PMID: 324802 Free article. No abstract available.

102

Stimulation of insulin secretion from mouse pancreatic islets, maintained in tissue culture, by the pituitary neurointermediate lobe of the genetically obese mouse (ob/ob).

Beloff-Chain A, Billingham N, Cawthorne MA. Beloff-Chain A, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1980 Jul 31;95(2):792-5. doi: 10.1016/0006-291x(80)90856-6. Biochem Biophys Res Commun. 1980. PMID: 6251818 No abstract available.

103

Increased insulin binding and glucose transport in white adipocytes isolated from C57B1/6 ob/ob mice treated with the thermogenic beta-adrenoceptor agonist BRL 26830.

Young P, King L, Cawthorne MA. Young P, et al. Among authors: cawthorne ma. Biochem Biophys Res Commun. 1985 Dec 17;133(2):457-61. doi: 10.1016/0006-291x(85)90928-3. Biochem Biophys Res Commun. 1985. PMID: 2867764

104

Assessment of Gi function in an animal model of non-insulin dependent diabetes.

Murphy GJ, Kirkham DM, Cawthorne MA, Young P. Murphy GJ, et al. Among authors: cawthorne ma. Biochem Soc Trans. 1990 Dec;18(6):1289-90. doi: 10.1042/bst0181289. Biochem Soc Trans. 1990. PMID: 2128483 No abstract available.

105

Important sites of lipogenesis in the mouse other than liver and white adipose tissue.

Hollands MA, Cawthorne MA. Hollands MA, et al. Among authors: cawthorne ma. Biochem J. 1981 May 15;196(2):645-7. doi: 10.1042/bj1960645. Biochem J. 1981. PMID: 7317003 Free PMC article.

106

Novel alpha 2-adrenoceptor antagonists show selectivity for alpha 2A- and alpha 2B-adrenoceptor subtypes.

Young P, Berge J, Chapman H, Cawthorne MA. Young P, et al. Among authors: cawthorne ma. Eur J Pharmacol. 1989 Sep 22;168(3):381-6. doi: 10.1016/0014-2999(89)90801-7. Eur J Pharmacol. 1989. PMID: 2573535

107

On the relationship between vitamin A and vitamin E in the rat.

Cawthorne MA, Bunyan J, Diplock AT, Murrell EA, Green J. Cawthorne MA, et al. Br J Nutr. 1968 Feb;22(1):133-43. doi: 10.1079/bjn19680016. Br J Nutr. 1968. PMID: 5645164 No abstract available.

108

Vitamin E and hepatotoxic agents. 1. Carbon tetrachloride and lipid peroxidation in the rat.

Green J, Bunyan J, Cawthorne MA, Diplock AT. Green J, et al. Among authors: cawthorne ma. Br J Nutr. 1969 Jun;23(2):297-307. doi: 10.1079/bjn19690037. Br J Nutr. 1969. PMID: 5787657 No abstract available.

109

Vitamin E and hepatotoxic agents. 2. Lipid peroxidation and poisoning with orotic acid, ethanol and thioacetamide in rats.

Bunyan J, Cawthorne MA, Diplock AT, Green J. Bunyan J, et al. Among authors: cawthorne ma. Br J Nutr. 1969 Jun;23(2):309-17. doi: 10.1079/bjn19690038. Br J Nutr. 1969. PMID: 5797388 No abstract available.

110

On the postulated peroxidation of unsaturated lipids in the tissues of vitamin E-deficient rats.

Bunyan J, Green J, Murrell EA, Diplock AT, Cawthorne MA. Bunyan J, et al. Among authors: cawthorne ma. Br J Nutr. 1968 Feb;22(1):97-110. doi: 10.1079/bjn19680012. Br J Nutr. 1968. PMID: 5645172 No abstract available.

111

Vitamin E and stress. 8. Nutritional effects of dietary stress with silver in vitamin E-deficient chicks and rats.

Bunyan J, Diplock AT, Cawthorne MA, Green J. Bunyan J, et al. Among authors: cawthorne ma. Br J Nutr. 1968 May;22(2):165-82. doi: 10.1079/bjn19680023. Br J Nutr. 1968. PMID: 5673539 No abstract available.

112

Effects of protein and vitamin E on haemoglobin formation in rats.

Bunyan J, Green J, Cawthorne MA. Bunyan J, et al. Among authors: cawthorne ma. Br J Nutr. 1968 Dec;22(4):751-5. doi: 10.1079/bjn19680084. Br J Nutr. 1968. PMID: 5712041 No abstract available.

113

Vitamin E and stress. 5. The effect of high and low oxygen tension on the metabolism of [14C]D-alpha-tocopherol in the vitamin E-deficient rat.

Cawthorne MA, Diplock AT, Muthy IR, Bunyan J, Murrell EA, Green J. Cawthorne MA, et al. Br J Nutr. 1967 Aug;21(3):671-9. doi: 10.1079/bjn19670069. Br J Nutr. 1967. PMID: 6052882 No abstract available.

114

Vitamin E and stress. 6. Iron overloading and the metabolism of D-alpha-tocopherol in the rat.

Diplock AT, Green J, Bunyan J, Cawthorne MA, Dawson J. Diplock AT, et al. Among authors: cawthorne ma. Br J Nutr. 1967 Aug;21(3):725-30. doi: 10.1079/bjn19670073. Br J Nutr. 1967. PMID: 6052886 No abstract available.

115

Vitamin E and stress. 7. The interrelationships between polyunsaturated fatty acid stress, vitamin A and vitamin E in the rat and the chick.

Green J, Muthy IR, Diplock AT, Bunyan J, Cawthorne MA, Murrell EA. Green J, et al. Among authors: cawthorne ma. Br J Nutr. 1967;21(4):845-64. doi: 10.1079/bjn19670086. Br J Nutr. 1967. PMID: 6077459 No abstract available.

116

In vivo effects of carbon tetrachloride and chloroform on liver and kidney glucose-6-phosphatase in mice.

Cawthorne MA, Palmer ED, Bunyan J, Green J. Cawthorne MA, et al. Biochem Pharmacol. 1971 Feb;20(2):494-6. doi: 10.1016/0006-2952(71)90090-6. Biochem Pharmacol. 1971. PMID: 4338362 No abstract available.

117

Effect of ethoxyquin on the carbon tetrachloride-induced changes in rat hepatic microsomal enzymes.

Cawthorne MA, Palmer ED, Green J. Cawthorne MA, et al. Biochem Pharmacol. 1973 Aug 15;22(16):2066-8. doi: 10.1016/0006-2952(73)90088-9. Biochem Pharmacol. 1973. PMID: 4353671 No abstract available.

118

Effect of 6-ethoxy 2,2,4-trimethyl-1,2-dihydroquinoline (ethoxyquin) on carbon tetrachloride metabolism in the rat.

Cawthorne MA, Palmer ED, Green J. Cawthorne MA, et al. Biochem Pharmacol. 1973 Apr 1;22(7):783-8. doi: 10.1016/0006-2952(73)90356-0. Biochem Pharmacol. 1973. PMID: 4692645 No abstract available.

119

Studies on unidentified growth factors. 1. Factor G, a growth factor for rats.

Bunyan J, Murrell EA, Cawthorne MA, Redman BT. Bunyan J, et al. Among authors: cawthorne ma. Br J Nutr. 1974 Mar;31(2):167-78. doi: 10.1079/bjn19740022. Br J Nutr. 1974. PMID: 4820971 No abstract available.

120

Studies on unidentified growth factors. 2. Progressin, a growth factor for chicks.

Bunyan J, Murrell EA, Cawthorne MA, Redman BT. Bunyan J, et al. Among authors: cawthorne ma. Br J Nutr. 1974 Mar;31(2):179-84. doi: 10.1079/bjn19740023. Br J Nutr. 1974. PMID: 4856578 No abstract available.

121

The effect of ethoxyquin on the mortality of sheep treated with DDT and carbon tetrachloride.

Cawthorne MA, Murrell EA, Bunyan J, Leiper JW, Green J, Watkins JH. Cawthorne MA, et al. Res Vet Sci. 1971 Nov;12(6):516-20. Res Vet Sci. 1971. PMID: 5145348 No abstract available.

122

Inhibition of thiabendazole metabolism in the rat.

Wilson CG, Parke DV, Green J, Cawthorne MA. Wilson CG, et al. Among authors: cawthorne ma. Xenobiotica. 1979 Jun;9(6):343-51. doi: 10.3109/00498257909038738. Xenobiotica. 1979. PMID: 494664

123

Adjuvant-induced arthritis and drug-metabolizing enzymes.

Cawthorne MA, Palmer ED, Green J. Cawthorne MA, et al. Biochem Pharmacol. 1976 Dec 15;25(24):2683-8. doi: 10.1016/0006-2952(76)90257-4. Biochem Pharmacol. 1976. PMID: 1008892 No abstract available.

124

The role of cytochrome P-450 in cholesterol biogenesis and catabolism.

Atkin SD, Palmer ED, English PD, Morgan B, Cawthorne MA, Green J. Atkin SD, et al. Among authors: cawthorne ma. Biochem J. 1972 Jun;128(2):237-42. doi: 10.1042/bj1280237. Biochem J. 1972. PMID: 5084788 Free PMC article.

125

Distribution of menaquinones in aerobic Micrococcaceae.

Jeffries L, Cawthorne MA, Harris M, Diplock AT, Green J, Price SA. Jeffries L, et al. Among authors: cawthorne ma. Nature. 1967 Jul 15;215(5098):257-9. doi: 10.1038/215257a0. Nature. 1967. PMID: 6059508 No abstract available.

126

Menaquinone-4 and -5 in a bacterium.

Cawthorne MA, Jeffries LR, Harris M, Price SA, Diplock AT, Green J. Cawthorne MA, et al. Biochem J. 1967 Aug;104(2):35contd-36c. doi: 10.1042/bj1040035c. Biochem J. 1967. PMID: 6048777 Free PMC article. No abstract available.

127

Reduced maximum capacity of glycolysis in brown adipose tissue of genetically obese, diabetic (db/db) mice and its restoration following treatment with a thermogenic beta-adrenoceptor agonist.

Young P, Cawthorne MA, Levy AL, Wilson K. Young P, et al. Among authors: cawthorne ma. FEBS Lett. 1984 Oct 15;176(1):16-20. doi: 10.1016/0014-5793(84)80903-5. FEBS Lett. 1984. PMID: 6149150 Free article.

128

Fatty acid synthesis in mice during the 24hr cycle and during meal-feeding.

Cornish S, Cawthorne MA. Cornish S, et al. Among authors: cawthorne ma. Horm Metab Res. 1978 Jul;10(4):286-90. doi: 10.1055/s-0028-1093416. Horm Metab Res. 1978. PMID: 567166

129

Characterization of a new, highly specific, beta 3-adrenergic receptor radioligand, [3H]SB 206606.

Muzzin P, Boss O, Mathis N, Revelli JP, Giacobino JP, Willcocks K, Badman GT, Cantello BC, Hindley RM, Cawthorne MA. Muzzin P, et al. Among authors: cawthorne ma. Mol Pharmacol. 1994 Aug;46(2):357-63. Mol Pharmacol. 1994. PMID: 8078497

130

Menaquinone determination in the taxonomy of micrococcaceae.

Jeffries L, Cawthorne MA, Harris M, Cook B, Diplock AT. Jeffries L, et al. Among authors: cawthorne ma. J Gen Microbiol. 1968 Dec;54(3):365-80. doi: 10.1099/00221287-54-3-365. J Gen Microbiol. 1968. PMID: 5709278 No abstract available.

131

The effects of 1-alkylimidazoles on hepatic drug-metabolizing enzyme activity.

Palmer ED, Cawthorne MA. Palmer ED, et al. Among authors: cawthorne ma. Xenobiotica. 1974 Apr;4(4):209-17. doi: 10.3109/00498257409062539. Xenobiotica. 1974. PMID: 4847029 No abstract available.

132

Taspoglutide, an analog of human glucagon-like Peptide-1 with enhanced stability and in vivo potency.

Sebokova E, Christ AD, Wang H, Sewing S, Dong JZ, Taylor J, Cawthorne MA, Culler MD. Sebokova E, et al. Among authors: cawthorne ma. Endocrinology. 2010 Jun;151(6):2474-82. doi: 10.1210/en.2009-1459. Epub 2010 Apr 9. Endocrinology. 2010. PMID: 20382695

133

The mouse SWISS-2D PAGE database: a tool for proteomics study of diabetes and obesity.

Sanchez JC, Chiappe D, Converset V, Hoogland C, Binz PA, Paesano S, Appel RD, Wang S, Sennitt M, Nolan A, Cawthorne MA, Hochstrasser DF. Sanchez JC, et al. Among authors: cawthorne ma. Proteomics. 2001 Jan;1(1):136-63. doi: 10.1002/1615-9861(200101)1:1<136::AID-PROT136>3.0.CO;2-1. Proteomics. 2001. PMID: 11680894

134

Treatment with the thiazolidinedione (BRL 49653) decreases insulin resistance in obese Zucker hindlimb.

Eldershaw TP, Rattigan S, Cawthorne MA, Buckingham RE, Colquhoun EQ, Clark MG. Eldershaw TP, et al. Among authors: cawthorne ma. Horm Metab Res. 1995 Apr;27(4):169-72. doi: 10.1055/s-2007-979932. Horm Metab Res. 1995. PMID: 7750898

135

Potential defect in the vascular control of nonshivering thermogenesis in the obese Zucker rat hind limb.

Eldershaw TP, Rattigan S, Dora KA, Colquhoun EQ, Clark MG, Cawthorne MA, Buckingham RE. Eldershaw TP, et al. Among authors: cawthorne ma. Can J Physiol Pharmacol. 1994 Dec;72(12):1567-73. doi: 10.1139/y94-225. Can J Physiol Pharmacol. 1994. PMID: 7736349

136

Does brown adipose tissue have a role to play in glucose homeostasis?

Cawthorne MA. Cawthorne MA. Proc Nutr Soc. 1989 Jul;48(2):207-14. doi: 10.1079/pns19890031. Proc Nutr Soc. 1989. PMID: 2678116 Review. No abstract available.

137

Lipid metabolism in diabetes.

Cawthorne MA. Cawthorne MA. Biochem Soc Trans. 1987 Jun;15(3):343-5. doi: 10.1042/bst0150343. Biochem Soc Trans. 1987. PMID: 3622911 No abstract available.

138

The determination of alpha-adrenergic receptor concentration on rat pancreatic islet cells.

Fyles JM, Cawthorne MA, Howell SL. Fyles JM, et al. Among authors: cawthorne ma. Biosci Rep. 1987 Jan;7(1):17-22. doi: 10.1007/BF01122723. Biosci Rep. 1987. PMID: 3040138

139

The characteristics of beta-adrenergic binding sites on pancreatic islets of Langerhans.

Fyles JM, Cawthorne MA, Howell SL. Fyles JM, et al. Among authors: cawthorne ma. J Endocrinol. 1986 Nov;111(2):263-70. doi: 10.1677/joe.0.1110263. J Endocrinol. 1986. PMID: 3025326

140

Brown adipose tissue, hibernation and obesity.

Cawthorne MA. Cawthorne MA. J R Soc Med. 1983 Mar;76(3):173-4. doi: 10.1177/014107688307600302. J R Soc Med. 1983. PMID: 6834366 Free PMC article. No abstract available.

141

Impairment of effects of vasopressin on [1-14C]oleate metabolism in hepatocytes from obese (ob/ob) mice.

Edwards MW, Cawthorne MA, Williamson DH. Edwards MW, et al. Among authors: cawthorne ma. Biochem J. 1981 Jul 15;198(1):239-42. doi: 10.1042/bj1980239. Biochem J. 1981. PMID: 7326000 Free PMC article.

142

Effects of vasopressin on lipogenesis in obese mice.

Edwards MW, Brooks SL, Gove CD, Hems DA, Cawthorne MA. Edwards MW, et al. Among authors: cawthorne ma. FEBS Lett. 1981 May 5;127(1):25-7. doi: 10.1016/0014-5793(81)80332-8. FEBS Lett. 1981. PMID: 6788601 Free article. No abstract available.

143

Catabolic effects of adrenaline and angiotensin II in the perfused liver of normal and genetically obese (ob/ob) mice.

Ma GY, Gove CD, Cawthorne MA, Hems DA. Ma GY, et al. Among authors: cawthorne ma. Clin Sci (Lond). 1979 May;56(5):493-9. doi: 10.1042/cs0560493. Clin Sci (Lond). 1979. PMID: 38934

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