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1993 | 1 |
1995 | 1 |
1997 | 3 |
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Page 1
CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents.
Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3642-9. doi: 10.1073/pnas.92.9.3642.
Proc Natl Acad Sci U S A. 1995.
PMID: 7731958
Free PMC article.
Review.
High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA.
Eis PS, Smith JA, Rydzewski JM, Case DA, Boger DL, Chazin WJ.
Eis PS, et al.
J Mol Biol. 1997 Sep 19;272(2):237-52. doi: 10.1006/jmbi.1997.1223.
J Mol Biol. 1997.
PMID: 9299351
Item in Clipboard
Catalysis of the CC-1065 and duocarmycin DNA alkylation reaction: DNA binding induced conformational change in the agent results in activation.
Boger DL, Garbaccio RM.
Boger DL, et al.
Bioorg Med Chem. 1997 Feb;5(2):263-76. doi: 10.1016/s0968-0896(96)00238-6.
Bioorg Med Chem. 1997.
PMID: 9061191
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Evaluation of functional analogs of CC-1065 and the duocarmycins incorporating the cross-linking 9a-chloromethyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e (C2BI) alkylation subunit.
Boger DL, Johnson DS, Palanki MS, Kitos PA, Chang J, Dowell P.
Boger DL, et al.
Bioorg Med Chem. 1993 Jul;1(1):27-38. doi: 10.1016/s0968-0896(00)82100-8.
Bioorg Med Chem. 1993.
PMID: 8081835
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CC-1065/duocarmycin and bleomycin A2 hybrid agents: lack of enhancement of DNA alkylation by attachment to noncomplementary DNA binding subunits.
Boger DL, Han N.
Boger DL, et al.
Bioorg Med Chem. 1997 Feb;5(2):233-43. doi: 10.1016/s0968-0896(96)00237-4.
Bioorg Med Chem. 1997.
PMID: 9061188
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