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Quoted phrase not found in phrase index: "Acute Myeloid Leukemia with Gene Mutations"
Page 1
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
Papaemmanuil E, Gerstung M, Bullinger L, Gaidzik VI, Paschka P, Roberts ND, Potter NE, Heuser M, Thol F, Bolli N, Gundem G, Van Loo P, Martincorena I, Ganly P, Mudie L, McLaren S, O'Meara S, Raine K, Jones DR, Teague JW, Butler AP, Greaves MF, Ganser A, Döhner K, Schlenk RF, Döhner H, Campbell PJ. Papaemmanuil E, et al. N Engl J Med. 2016 Jun 9;374(23):2209-2221. doi: 10.1056/NEJMoa1516192. N Engl J Med. 2016. PMID: 27276561 Free PMC article. Clinical Trial.
BACKGROUND: Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemia (AML). Our next challenge is to understand how this genetic diversity defines the pathophysiology of AML and informs clinical practice …
BACKGROUND: Recent studies have provided a detailed census of genes that are mutated in acute myeloid leukemi
The International Consensus Classification of acute myeloid leukemia.
Weinberg OK, Porwit A, Orazi A, Hasserjian RP, Foucar K, Duncavage EJ, Arber DA. Weinberg OK, et al. Virchows Arch. 2023 Jan;482(1):27-37. doi: 10.1007/s00428-022-03430-4. Epub 2022 Oct 20. Virchows Arch. 2023. PMID: 36264379 Review.
Acute myeloid leukemias (AMLs) are overlapping hematological neoplasms associated with rapid onset, progressive, and frequently chemo-resistant disease. ...A group with expertise in the clinical, pathologic, and genetic aspects of these disorders developed the Inter
Acute myeloid leukemias (AMLs) are overlapping hematological neoplasms associated with rapid onset, progressive, and frequentl
Molecular biomarkers in acute myeloid leukemia.
Prada-Arismendy J, Arroyave JC, Röthlisberger S. Prada-Arismendy J, et al. Blood Rev. 2017 Jan;31(1):63-76. doi: 10.1016/j.blre.2016.08.005. Epub 2016 Sep 2. Blood Rev. 2017. PMID: 27639498 Review.
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. ...This review summarizes the most relevant molecular (genetic, epigenetic, and protein) biomarkers associated with acute myeloid leukemia and discuss
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. ...This review summarizes the m
NPM1-mutated acute myeloid leukemia: from bench to bedside.
Falini B, Brunetti L, Sportoletti P, Martelli MP. Falini B, et al. Blood. 2020 Oct 8;136(15):1707-1721. doi: 10.1182/blood.2019004226. Blood. 2020. PMID: 32609823 Free article. Review.
NPM1 mutations represent the most common genetic lesion in adult acute myeloid leukemia (AML; about one third of cases), and they act deterministically to cause the aberrant cytoplasmic delocalization of NPM1 mutants. ...The contribution of HOX gene
NPM1 mutations represent the most common genetic lesion in adult acute myeloid leukemia (AML; about one third of …
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
Cancer Genome Atlas Research Network; Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson A, Hoadley K, Triche TJ Jr, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, Klco JM, Koboldt DC, Kanchi KL, Kulkarni S, Lamprecht TL, Larson DE, Lin L, Lu C, McLellan MD, McMichael JF, Payton J, Schmidt H, Spencer DH, Tomasson MH, Wallis JW, Wartman LD, Watson MA, Welch J, Wendl MC, Ally A, Balasundaram M, Birol I, Butterfield Y, Chiu R, Chu A, Chuah E, Chun HJ, Corbett R, Dhalla N, Guin R, He A, Hirst C, Hirst M, Holt RA, Jones S, Karsan A, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Mungall K, Parker J, Pleasance E, Plettner P, Schein J, Stoll D, Swanson L, Tam A, Thiessen N, Varhol R, Wye N, Zhao Y, Gabriel S, Getz G, Sougnez C, Zou L, Leiserson MD, Vandin F, Wu HT, Applebaum F, Baylin SB, Akbani R, Broom BM, Chen K, Motter TC, Nguyen K, Weinstein JN, Zhang N, Ferguson ML, Adams C, Black A, Bowen J, Gastier-Foster J, Grossman T, Lichtenberg T, Wise L, Davidsen T, Demchok JA, Shaw KR, Sheth M, Sofia HJ, Yang L, Downing JR, Eley G. Cancer Genome Atlas Research Network, et al. N Engl J Med. 2013 May 30;368(22):2059-74. doi: 10.1056/NEJMoa1301689. Epub 2013 May 1. N Engl J Med. 2013. PMID: 23634996 Free PMC article.
BACKGROUND: Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. ...Nearly all samples had at least 1 nonsynonymous mutation in one of nine categories of genes that are almost certainly relevan …
BACKGROUND: Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. .. …
Acute myeloid leukaemia.
Khwaja A, Bjorkholm M, Gale RE, Levine RL, Jordan CT, Ehninger G, Bloomfield CD, Estey E, Burnett A, Cornelissen JJ, Scheinberg DA, Bouscary D, Linch DC. Khwaja A, et al. Nat Rev Dis Primers. 2016 Mar 10;2:16010. doi: 10.1038/nrdp.2016.10. Nat Rev Dis Primers. 2016. PMID: 27159408 Review.
Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived from primitive haematopoietic stem cells or progenitor cells. ...The genomic landscape of AML has been determined and genetic instability is infrequent with a relatively smal
Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived from primitive haematopoietic stem
How I investigate acute myeloid leukemia.
Narayanan D, Weinberg OK. Narayanan D, et al. Int J Lab Hematol. 2020 Feb;42(1):3-15. doi: 10.1111/ijlh.13135. Epub 2019 Dec 10. Int J Lab Hematol. 2020. PMID: 31820579 Review.
Acute myeloid leukemia (AML) is a neoplasm of immature myeloid cells and is associated with a wide variety of clinical presentations, morphological features, immunophenotypes, and genetic findings. Recent advances in identification of cytogenetic abnor
Acute myeloid leukemia (AML) is a neoplasm of immature myeloid cells and is associated with a wide variety of cl
A concise review on the molecular genetics of acute myeloid leukemia.
Padmakumar D, Chandraprabha VR, Gopinath P, Vimala Devi ART, Anitha GRJ, Sreelatha MM, Padmakumar A, Sreedharan H. Padmakumar D, et al. Leuk Res. 2021 Dec;111:106727. doi: 10.1016/j.leukres.2021.106727. Epub 2021 Oct 16. Leuk Res. 2021. PMID: 34700049 Review.
Acute myeloid leukemia (AML) is the most common acute leukemia in adults that affects the myeloid lineage. ...These gene mutations serve as important prognostic markers as well as potential therapeutic targets. ...
Acute myeloid leukemia (AML) is the most common acute leukemia in adults that affects the myeloid
Genomics of Acute Myeloid Leukemia Diagnosis and Pathways.
Bullinger L, Döhner K, Döhner H. Bullinger L, et al. J Clin Oncol. 2017 Mar 20;35(9):934-946. doi: 10.1200/JCO.2016.71.2208. Epub 2017 Feb 13. J Clin Oncol. 2017. PMID: 28297624 Review.
In recent years, our understanding of the molecular pathogenesis of myeloid neoplasms, including acute myeloid leukemia (AML), has been greatly advanced by genomics discovery studies that use novel high-throughput sequencing techniques. ...Mutations
In recent years, our understanding of the molecular pathogenesis of myeloid neoplasms, including acute myeloid leuke
Leukemia secondary to myeloproliferative neoplasms.
Dunbar AJ, Rampal RK, Levine R. Dunbar AJ, et al. Blood. 2020 Jul 2;136(1):61-70. doi: 10.1182/blood.2019000943. Blood. 2020. PMID: 32430500 Free PMC article. Review.
Secondary acute myeloid leukemias (AMLs) evolving from an antecedent myeloproliferative neoplasm (MPN) are characterized by a unique set of cytogenetic and molecular features distinct from de novo AML. ...Here, we review known risk factors for the development of leu …
Secondary acute myeloid leukemias (AMLs) evolving from an antecedent myeloproliferative neoplasm (MPN) are characterized by a …
2,729 results