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1998 36
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2005 29
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2007 45
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2009 38
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1,287 results

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Quoted phrase not found in phrase index: "Childhood Gliomatosis Cerebri"
Page 1
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N. Aygun N. Curr Pediatr Rev. 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. Curr Pediatr Rev. 2018. PMID: 29380702 Review.
Neuroblastoma usually occurs sporadically, but familial cases are also observed. ALK and PHOX2B germline mutations can cause hereditary neuroblastoma, while a common genetic variation in chromosome 6p22 is associated to sporadic neuroblastoma. ...This embryonic malignancy …
Neuroblastoma usually occurs sporadically, but familial cases are also observed. ALK and PHOX2B germline mutations can cause heredita …
Origin and initiation mechanisms of neuroblastoma.
Tsubota S, Kadomatsu K. Tsubota S, et al. Cell Tissue Res. 2018 May;372(2):211-221. doi: 10.1007/s00441-018-2796-z. Epub 2018 Feb 14. Cell Tissue Res. 2018. PMID: 29445860 Review.
Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal medulla and paravertebral sympathetic ganglia in early childhood. Extensive studies have revealed the molecular characteristics of human neuroblastomas, including abnormalities at genom …
Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal medulla and paravertebral sympathetic ganglia in ear …
The immune cell atlas of human neuroblastoma.
Verhoeven BM, Mei S, Olsen TK, Gustafsson K, Valind A, Lindström A, Gisselsson D, Fard SS, Hagerling C, Kharchenko PV, Kogner P, Johnsen JI, Baryawno N. Verhoeven BM, et al. Cell Rep Med. 2022 Jun 21;3(6):100657. doi: 10.1016/j.xcrm.2022.100657. Epub 2022 Jun 9. Cell Rep Med. 2022. PMID: 35688160 Free PMC article.
In contrast to adult cancers and previous NB studies, we show an increase in inflammatory monocyte cell state when contrasting normal and tumor tissue, while no differences in cytotoxicity and exhaustion score for T cells, nor in Treg activity, are observed. Our rec …
In contrast to adult cancers and previous NB studies, we show an increase in inflammatory monocyte cell state when contrasting normal and tu …
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.
Kildisiute G, Kholosy WM, Young MD, Roberts K, Elmentaite R, van Hooff SR, Pacyna CN, Khabirova E, Piapi A, Thevanesan C, Bugallo-Blanco E, Burke C, Mamanova L, Keller KM, Langenberg-Ververgaert KPS, Lijnzaad P, Margaritis T, Holstege FCP, Tas ML, Wijnen MHWA, van Noesel MM, Del Valle I, Barone G, van der Linden R, Duncan C, Anderson J, Achermann JC, Haniffa M, Teichmann SA, Rampling D, Sebire NJ, He X, de Krijger RR, Barker RA, Meyer KB, Bayraktar O, Straathof K, Molenaar JJ, Behjati S. Kildisiute G, et al. Sci Adv. 2021 Feb 5;7(6):eabd3311. doi: 10.1126/sciadv.abd3311. Print 2021 Feb. Sci Adv. 2021. PMID: 33547074 Free PMC article.
Neuroblastoma is a childhood cancer that resembles developmental stages of the neural crest. ...We substantiated our findings in 650 neuroblastoma bulk transcriptomes and by integrating canonical features of the neuroblastoma genome with transcriptional signals. Overall, o …
Neuroblastoma is a childhood cancer that resembles developmental stages of the neural crest. ...We substantiated our findings in 650 …
Congenital Neuroblastoma.
Minakova E, Lang J. Minakova E, et al. Neoreviews. 2020 Nov;21(11):e716-e727. doi: 10.1542/neo.21-11-e716. Neoreviews. 2020. PMID: 33139509
Neuroblastoma is the most common extracranial solid tumor diagnosed during childhood and gives rise to various heterogeneous tumors along the sympathoadrenal axis. ...This article will provide information on the pathogenesis and variable clinical presentation of congenital …
Neuroblastoma is the most common extracranial solid tumor diagnosed during childhood and gives rise to various heterogeneous tumors a …
Long-term survival and cure fraction estimates for childhood cancer in Europe (EUROCARE-6): results from a population-based study.
Botta L, Gatta G, Capocaccia R, Stiller C, Cañete A, Dal Maso L, Innos K, Mihor A, Erdmann F, Spix C, Lacour B, Marcos-Gragera R, Murray D, Rossi S; EUROCARE-6 Working Group. Botta L, et al. Lancet Oncol. 2022 Dec;23(12):1525-1536. doi: 10.1016/S1470-2045(22)00637-4. Epub 2022 Nov 16. Lancet Oncol. 2022. PMID: 36400102
BACKGROUND: The EUROCARE-5 study revealed disparities in childhood cancer survival among European countries, giving rise to important initiatives across Europe to reduce the gap. ...The cure fraction for patients with childhood cancer increased over time from 74% (9 …
BACKGROUND: The EUROCARE-5 study revealed disparities in childhood cancer survival among European countries, giving rise to important …
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM. Waszak SM, et al. Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9. Lancet Oncol. 2018. PMID: 29753700 Free PMC article.
Patients with germline mutations in SUFU and PTCH1 mostly developed infant MB(SHH). Germline TP53 mutations presented only in childhood patients in the MB(SHH) subgroup and explained more than half (eight [57%] of 14) of all chromothripsis events in this subgroup. Germline …
Patients with germline mutations in SUFU and PTCH1 mostly developed infant MB(SHH). Germline TP53 mutations presented only in childhood …
Neonatal Neuroblastoma.
Davidoff AM. Davidoff AM. Clin Perinatol. 2021 Mar;48(1):101-115. doi: 10.1016/j.clp.2020.11.006. Epub 2021 Jan 12. Clin Perinatol. 2021. PMID: 33583499 Review.
Despite the disproportionate contribution of neuroblastoma to childhood cancer deaths, neonatal neuroblastoma has a favorable prognosis, often with little or no therapy required. ...
Despite the disproportionate contribution of neuroblastoma to childhood cancer deaths, neonatal neuroblastoma has a favorable prognos …
Cancer predictive studies.
Amelio I, Bertolo R, Bove P, Candi E, Chiocchi M, Cipriani C, Di Daniele N, Ganini C, Juhl H, Mauriello A, Marani C, Marshall J, Montanaro M, Palmieri G, Piacentini M, Sica G, Tesauro M, Rovella V, Tisone G, Shi Y, Wang Y, Melino G. Amelio I, et al. Biol Direct. 2020 Oct 14;15(1):18. doi: 10.1186/s13062-020-00274-3. Biol Direct. 2020. PMID: 33054808 Free PMC article. Review.
The identification of individual or clusters of predictive genetic alterations might help in defining the outcome of cancer treatment, allowing for the stratification of patients into distinct cohorts for selective therapeutic protocols. Neuroblastoma (NB) is the most comm …
The identification of individual or clusters of predictive genetic alterations might help in defining the outcome of cancer treatment …
Childhood medulloblastoma.
Massimino M, Giangaspero F, Garrè ML, Gandola L, Poggi G, Biassoni V, Gatta G, Rutkowski S. Massimino M, et al. Crit Rev Oncol Hematol. 2011 Jul;79(1):65-83. doi: 10.1016/j.critrevonc.2010.07.010. Epub 2010 Dec 3. Crit Rev Oncol Hematol. 2011. PMID: 21129995 Review.
Among all the childhood central nervous system tumours, medulloblastoma and other neuroectodermal tumours account for 16-25% of cases. ...Current and currently planned clinical trials will:define molecular and biological markers that improve outcome prediction in pa …
Among all the childhood central nervous system tumours, medulloblastoma and other neuroectodermal tumours account for 16-25% of cases …
1,287 results