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Quoted phrase not found in phrase index: "Chondroitin sulfate excretion in urine"
Page 1
Quantification of orally administered chondroitin sulfate oligosaccharides in human plasma and urine.
Mizuta H, Kawahara S, Tsutsumi N, Miyamoto N. Mizuta H, et al. Glycobiology. 2023 Oct 29;33(9):755-763. doi: 10.1093/glycob/cwad054. Glycobiology. 2023. PMID: 37440435
Four types of chondroitin sulfate with varying molecular weight [chondroitin sulfate tetrasaccharide (MW. 980), CSOS-1 (MW. 1,500), CSOS-2 (MW. 2,800), and HMWCS (MW. 70,000)] were orally administered and quantified in plasma and urine. ...Quant …
Four types of chondroitin sulfate with varying molecular weight [chondroitin sulfate tetrasaccharide (MW. 980), …
Urinary sulfated glycosaminoglycan insufficiency and chondroitin sulfate supplement in urolithiasis.
Dissayabutra T, Kalpongnukul N, Chindaphan K, Srisa-Art M, Ungjaroenwathana W, Kaewwongse M, Iampenkhae K, Tosukhowong P. Dissayabutra T, et al. PLoS One. 2019 Mar 7;14(3):e0213180. doi: 10.1371/journal.pone.0213180. eCollection 2019. PLoS One. 2019. PMID: 30845174 Free PMC article.
Familial members of urolithiasis have high risk for stone development. We observed the low sulfated glycosaminoglycan (GAG) excretion in urolithiasis patients and their descendants. In this study, we investigated urinary excretion of sulfated GAG, chondroitin …
Familial members of urolithiasis have high risk for stone development. We observed the low sulfated glycosaminoglycan (GAG) excretion …
Oral treatment for mucopolysaccharidosis VI: Outcomes of the first phase IIa study with odiparcil.
Guffon N, Chowdary P, Teles EL, Hughes D, Hennermann JB, Huot-Marchand P, Faudot-Vernier E, Lacombe O, Fiquet A, Richard MP, Abitbol JL, Tallandier M, Hendriksz CJ. Guffon N, et al. J Inherit Metab Dis. 2022 Mar;45(2):340-352. doi: 10.1002/jimd.12467. Epub 2021 Dec 30. J Inherit Metab Dis. 2022. PMID: 34910312 Clinical Trial.
Odiparcil is an orally available small molecule that results in the synthesis of odiparcil-linked GAGs facilitating their excretion and reducing cellular and tissue GAG accumulation. Improve MPS treatment was a Phase 2a study of the safety, pharmacokinetics/pharmacodynamic …
Odiparcil is an orally available small molecule that results in the synthesis of odiparcil-linked GAGs facilitating their excretion a …
Urinary glycosaminoglycan excretion in healthy subjects and in patients with mucopolysaccharidoses.
Gallegos-Arreola MP, Machorro-Lazo MV, Flores-Martínez SE, Zúñiga-González GM, Figuera LE, González-Noriega A, Sánchez-Corona J. Gallegos-Arreola MP, et al. Arch Med Res. 2000 Sep-Oct;31(5):505-10. doi: 10.1016/s0188-4409(00)00104-1. Arch Med Res. 2000. PMID: 11179586
A different tendency was present in patients with MPS, because levels of GAG excretion in this group were higher (by four standard deviations up) compared with healthy individuals. The electrophoretic patterns of urinary GAGs in healthy subjects showed that the higher leve …
A different tendency was present in patients with MPS, because levels of GAG excretion in this group were higher (by four standard de …
Dermatan sulphate in urine reflects the extent of skin affection in psoriasis.
Poulsen JH, Cramers MK. Poulsen JH, et al. Clin Chim Acta. 1982 Dec 9;126(2):119-26. doi: 10.1016/0009-8981(82)90027-4. Clin Chim Acta. 1982. PMID: 6817946
By using a simple method based on susceptibility to chondroitinases the excretion of dermatan sulphate, chondroitin-4/6-sulphate and heparan sulphate in the psoriatics was found to be increased with 104, 62 and 47% from uronic acid mean excretions of 1.97, 6. …
By using a simple method based on susceptibility to chondroitinases the excretion of dermatan sulphate, chondroitin-4/6-sulpha …
Importance of the combined urinary procedure for the diagnosis of Mucopolysaccharidoses.
Zampini L, Padella L, Marchesiello RL, Santoro L, Monachesi C, Giovagnoni A, Catassi C, Gabrielli O, Coppa GV, Galeazzi T. Zampini L, et al. Clin Chim Acta. 2017 Jan;464:165-169. doi: 10.1016/j.cca.2016.11.024. Epub 2016 Nov 16. Clin Chim Acta. 2017. PMID: 27865974
BACKGROUND: Mucopolysaccharidoses are characterized by the accumulation of undegraded glycosaminoglycans in lysosomes in multiple organs and by their excretion in high amounts in urine. The aim of this study is to determine if this simple, reliable and reprod …
BACKGROUND: Mucopolysaccharidoses are characterized by the accumulation of undegraded glycosaminoglycans in lysosomes in multiple organs and …
Increased excretion of urinary glycosaminoglycans in meningococcal septicemia and their relationship to proteinuria.
Oragui EE, Nadel S, Kyd P, Levin M. Oragui EE, et al. Crit Care Med. 2000 Aug;28(8):3002-8. doi: 10.1097/00003246-200008000-00054. Crit Care Med. 2000. PMID: 10966286
The size-distribution and nature of glycosaminoglycans were defined by Polyacrylamide Gel Electrophoresis and specific enzyme digestion. Urinary excretion of heparan sulfate, chondroitin-4-sulfate, and chondroitin-6-sulfate were significa …
The size-distribution and nature of glycosaminoglycans were defined by Polyacrylamide Gel Electrophoresis and specific enzyme digestion. Uri …
Urine bikunin as a marker of renal impairment in Fabry's disease.
Lepedda AJ, Fancellu L, Zinellu E, De Muro P, Nieddu G, Deiana GA, Canu P, Concolino D, Sestito S, Formato M, Sechi G. Lepedda AJ, et al. Biomed Res Int. 2013;2013:205948. doi: 10.1155/2013/205948. Epub 2013 Jun 12. Biomed Res Int. 2013. PMID: 23841057 Free PMC article.
In this respect, no differences were evidenced in plasma chondroitin sulfate isomers level/structure indicating a likely direct kidney involvement. Noteworthy, urine bikunin levels are higher in patients since early symptoms of renal impairment occur (protein …
In this respect, no differences were evidenced in plasma chondroitin sulfate isomers level/structure indicating a likely direc …
Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes.
Lepedda AJ, Nieddu G, Rocchiccioli S, Ucciferri N, Idini M, De Muro P, Formato M. Lepedda AJ, et al. J Diabetes Res. 2018 Feb 6;2018:9378515. doi: 10.1155/2018/9378515. eCollection 2018. J Diabetes Res. 2018. PMID: 29541644 Free PMC article.
In the last years, we reported an association among urinary trypsin inhibitor (UTI), a small proteoglycan that plays pleiotropic roles in many inflammatory processes, and both type 1 and 2 diabetes and developed a method for its direct quantitation and structural characterization …
In the last years, we reported an association among urinary trypsin inhibitor (UTI), a small proteoglycan that plays pleiotropic roles in ma …
Acid glycosaminoglycan (aGAG) excretion is increased in children with autism spectrum disorder, and it can be controlled by diet.
Endreffy I, Bjørklund G, Dicső F, Urbina MA, Endreffy E. Endreffy I, et al. Metab Brain Dis. 2016 Apr;31(2):273-8. doi: 10.1007/s11011-015-9745-2. Epub 2015 Oct 14. Metab Brain Dis. 2016. PMID: 26464064
Proteoglycans (PG) regulate diverse functions in the central nervous system. Heparan sulfate (HS) and chondroitin sulfate (CS) are two major GAGs present in the PGs of the CNS. ...Within groups (controls and ASD), no gender differences in GAG excretion …
Proteoglycans (PG) regulate diverse functions in the central nervous system. Heparan sulfate (HS) and chondroitin sulfate …
38 results