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Page 1
Collapsing glomerulopathy: update.
Morales E, Alonso M, Gutiérrez E. Morales E, et al. Med Clin (Barc). 2019 May 3;152(9):361-367. doi: 10.1016/j.medcli.2018.10.021. Epub 2018 Dec 13. Med Clin (Barc). 2019. PMID: 30554809 Review. English, Spanish.
Collapsing glomerulopathy (CG) is a rare entity as a glomerular disease. ...
Collapsing glomerulopathy (CG) is a rare entity as a glomerular disease. ...
COVID-19-Associated Glomerular Disease.
Shetty AA, Tawhari I, Safar-Boueri L, Seif N, Alahmadi A, Gargiulo R, Aggarwal V, Usman I, Kisselev S, Gharavi AG, Kanwar Y, Quaggin SE. Shetty AA, et al. J Am Soc Nephrol. 2021 Jan;32(1):33-40. doi: 10.1681/ASN.2020060804. Epub 2020 Nov 19. J Am Soc Nephrol. 2021. PMID: 33214201 Free PMC article.
BACKGROUND: Studies have documented AKI with high-grade proteinuria in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In some patients, biopsies have revealed collapsing glomerulopathy, a distinct form of glomerular injury that …
BACKGROUND: Studies have documented AKI with high-grade proteinuria in patients with severe acute respiratory syndrome coronavirus 2 (SARS-C …
Digital spatial profiling of collapsing glomerulopathy.
Smith KD, Prince DK, Henriksen KJ, Nicosia RF, Alpers CE, Akilesh S. Smith KD, et al. Kidney Int. 2022 May;101(5):1017-1026. doi: 10.1016/j.kint.2022.01.033. Epub 2022 Feb 26. Kidney Int. 2022. PMID: 35227689 Free PMC article.
Collapsing glomerulopathy is a histologically distinct variant of focal and segmental glomerulosclerosis that presents with heavy proteinuria and portends a poor prognosis. Collapsing glomerulopathy can be triggered by viral infections such as HIV or S …
Collapsing glomerulopathy is a histologically distinct variant of focal and segmental glomerulosclerosis that presents with he …
Acute Kidney Injury in COVID-19.
Głowacka M, Lipka S, Młynarska E, Franczyk B, Rysz J. Głowacka M, et al. Int J Mol Sci. 2021 Jul 28;22(15):8081. doi: 10.3390/ijms22158081. Int J Mol Sci. 2021. PMID: 34360866 Free PMC article. Review.
Recent studies have confirmed the direct entry of SARS-CoV-2 into the renal cells, namely podocytes and proximal tubular cells, but this is not the only pathomechanism of kidney damage. Hypovolemia, cytokine storm and collapsing glomerulopathy also play an important …
Recent studies have confirmed the direct entry of SARS-CoV-2 into the renal cells, namely podocytes and proximal tubular cells, but this is …
Malaria, Collapsing Glomerulopathy, and Focal and Segmental Glomerulosclerosis.
Amoura A, Moktefi A, Halfon M, Karras A, Rafat C, Gibier JB, Gleeson PJ, Servais A, Argy N, Maillé P, Belenfant X, Gueutin V, Delpierre A, Tricot L, El Karoui K, Jourde-Chiche N, Houze S, Sahali D, Audard V. Amoura A, et al. Clin J Am Soc Nephrol. 2020 Jul 1;15(7):964-972. doi: 10.2215/CJN.00590120. Epub 2020 May 22. Clin J Am Soc Nephrol. 2020. PMID: 32444394 Free PMC article.
Pathologic findings included FSGS in 21 patients and minimal change nephrotic syndrome in 2 patients. Among patients with FSGS, 18 had collapsing glomerulopathy (including 9 patients with HIV-associated nephropathy). ...CONCLUSIONS: In patients of African ancestry, …
Pathologic findings included FSGS in 21 patients and minimal change nephrotic syndrome in 2 patients. Among patients with FSGS, 18 had co …
The metabolic effects of APOL1 in humans.
Adeva-Andany MM, Funcasta-Calderón R, Fernández-Fernández C, Ameneiros-Rodríguez E, Vila-Altesor M, Castro-Quintela E. Adeva-Andany MM, et al. Pflugers Arch. 2023 Aug;475(8):911-932. doi: 10.1007/s00424-023-02821-z. Epub 2023 Jun 1. Pflugers Arch. 2023. PMID: 37261508 Free PMC article. Review.
Harboring apolipoprotein L1 (APOL1) variants coded by the G1 or G2 alleles of the APOL1 gene increases the risk for collapsing glomerulopathy, focal segmental glomerulosclerosis, albuminuria, chronic kidney disease, and accelerated kidney function decline towards en …
Harboring apolipoprotein L1 (APOL1) variants coded by the G1 or G2 alleles of the APOL1 gene increases the risk for collapsing glo …
Treatment potential in APOL1-associated nephropathy.
Friedman DJ, Ma L, Freedman BI. Friedman DJ, et al. Curr Opin Nephrol Hypertens. 2022 Sep 1;31(5):442-448. doi: 10.1097/MNH.0000000000000816. Epub 2022 Jul 11. Curr Opin Nephrol Hypertens. 2022. PMID: 35894278 Review.
RECENT FINDINGS: Since the 2010 discovery of APOL1 as a cause of nondiabetic nephropathy in individuals with sub-Saharan African ancestry, it has become apparent that aggressive hypertension control, renin-angiotensin system blockade, steroids and conventional immunosuppressive a …
RECENT FINDINGS: Since the 2010 discovery of APOL1 as a cause of nondiabetic nephropathy in individuals with sub-Saharan African ancestry, i …
Collapsing Focal Segmental Glomerulosclerosis in Viral Infections.
Muehlig AK, Gies S, Huber TB, Braun F. Muehlig AK, et al. Front Immunol. 2022 Jan 13;12:800074. doi: 10.3389/fimmu.2021.800074. eCollection 2021. Front Immunol. 2022. PMID: 35095882 Free PMC article. Review.
Collapsing glomerulopathy represents a special variant of the proteinuric kidney disease focal segmental glomerulosclerosis (FSGS). ...
Collapsing glomerulopathy represents a special variant of the proteinuric kidney disease focal segmental glomerulosclerosis (F …
Pathogenesis of coronavirus disease 2019-associated kidney injury.
Smith KD, Akilesh S. Smith KD, et al. Curr Opin Nephrol Hypertens. 2021 May 1;30(3):324-331. doi: 10.1097/MNH.0000000000000708. Curr Opin Nephrol Hypertens. 2021. PMID: 33767060 Review.
Severe COVID-19-associated acute kidney injury is likely multifactorial and results from the physiologic disturbances and therapies used to treat this illness. COVID-19-associated collapsing glomerulopathy (COVAN) is seen almost exclusively in patients with apolipop …
Severe COVID-19-associated acute kidney injury is likely multifactorial and results from the physiologic disturbances and therapies used to …
AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk Genotype.
Wu H, Larsen CP, Hernandez-Arroyo CF, Mohamed MMB, Caza T, Sharshir M, Chughtai A, Xie L, Gimenez JM, Sandow TA, Lusco MA, Yang H, Acheampong E, Rosales IA, Colvin RB, Fogo AB, Velez JCQ. Wu H, et al. J Am Soc Nephrol. 2020 Aug;31(8):1688-1695. doi: 10.1681/ASN.2020050558. Epub 2020 Jun 19. J Am Soc Nephrol. 2020. PMID: 32561682 Free PMC article.
At biopsy day, mean serum creatinine was 6.5 mg/dl and mean urine protein-creatinine ratio was 11.5 g. Kidney biopsy specimens showed collapsing glomerulopathy, extensive foot process effacement, and focal/diffuse acute tubular injury. ...Five patients needed dialys …
At biopsy day, mean serum creatinine was 6.5 mg/dl and mean urine protein-creatinine ratio was 11.5 g. Kidney biopsy specimens showed col …
91 results