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179 results

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Page 1
New Insights into the Pathogenesis of Mastocytosis: Emerging Concepts in Diagnosis and Therapy.
Valent P, Akin C, Sperr WR, Horny HP, Arock M, Metcalfe DD, Galli SJ. Valent P, et al. Annu Rev Pathol. 2023 Jan 24;18:361-386. doi: 10.1146/annurev-pathmechdis-031521-042618. Epub 2022 Oct 21. Annu Rev Pathol. 2023. PMID: 36270293 Free article. Review.
Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and accumulation of clonal mast cells (MCs) in various organ systems. The disease may present as cutaneous mastocytosis or systemic mastocytosis (SM). On the basis of histopathologica …
Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and accumulation of clonal mast cells (MCs) in various or …
Pediatric mastocytosis.
Hussain SH. Hussain SH. Curr Opin Pediatr. 2020 Aug;32(4):531-538. doi: 10.1097/MOP.0000000000000922. Curr Opin Pediatr. 2020. PMID: 32692050 Review.
KIT mutations are found in the majority of pediatric cutaneous mastocytosis but are not correlated with prognosis. Serum tryptase levels may be elevated in pediatric cutaneous mastocytosis patients without systemic mastocytosis. ...The low risk of NSAI …
KIT mutations are found in the majority of pediatric cutaneous mastocytosis but are not correlated with prognosis. Serum trypt …
Mastocytosis.
Abid A, Malone MA, Curci K. Abid A, et al. Prim Care. 2016 Sep;43(3):505-18. doi: 10.1016/j.pop.2016.04.007. Prim Care. 2016. PMID: 27545739 Review.
There are no therapies that change the natural course of mastocytosis. For cutaneous mastocytosis, treatment is conservative and aimed at symptom relief....
There are no therapies that change the natural course of mastocytosis. For cutaneous mastocytosis, treatment is conservative a …
Perioperative management of mastocytosis.
Lau S, Sprung J, Volcheck GW, Butterfield JH, Divekar RD, Weingarten TN. Lau S, et al. J Anesth. 2023 Oct;37(5):741-748. doi: 10.1007/s00540-023-03228-x. Epub 2023 Jul 19. J Anesth. 2023. PMID: 37466804 Review.
Pediatric and Hereditary Mastocytosis.
Renke J, Irga-Jaworska N, Lange M. Renke J, et al. Immunol Allergy Clin North Am. 2023 Nov;43(4):665-679. doi: 10.1016/j.iac.2023.04.001. Epub 2023 May 19. Immunol Allergy Clin North Am. 2023. PMID: 37758405 Review.
To a large extent, the clinical picture of pediatric mastocytosis depends on the age at which it is diagnosed. A neonate with diffuse cutaneous mastocytosis may frequently present in a severe state requiring treatment. ...
To a large extent, the clinical picture of pediatric mastocytosis depends on the age at which it is diagnosed. A neonate with diffuse cut …
Pediatric Mastocytosis: Recognition and Management.
Schaffer JV. Schaffer JV. Am J Clin Dermatol. 2021 Mar;22(2):205-220. doi: 10.1007/s40257-020-00581-5. Am J Clin Dermatol. 2021. PMID: 33492611 Review.
This article reviews the molecular pathogenesis, skin findings, mast cell mediator-related symptoms, evaluation, and management of childhood-onset mastocytosis, noting differences from adult-onset disease. Current classification of cutaneous mastocytosis and the nat …
This article reviews the molecular pathogenesis, skin findings, mast cell mediator-related symptoms, evaluation, and management of childhood …
Pediatric mastocytosis.
Kettelhut BV, Metcalfe DD. Kettelhut BV, et al. J Invest Dermatol. 1991 Mar;96(3 Suppl):15S-18S; discussion 18S, 60S-65S. doi: 10.1111/1523-1747.ep12468942. J Invest Dermatol. 1991. PMID: 16799603 Free article. Review.
The typical presentation of pediatric-onset mastocytosis consists of cutaneous manifestations: either a solitary mastocytoma, urticaria pigmentosa, or, less commonly, diffuse cutaneous mastocytosis. Particularly in infants, bullous eruptions may occur. ...
The typical presentation of pediatric-onset mastocytosis consists of cutaneous manifestations: either a solitary mastocytoma, urticaria pigm …
Pediatric mastocytosis.
Kettelhut BV, Metcalfe DD. Kettelhut BV, et al. J Invest Dermatol. 1991 Mar;96(3):15S-18S. J Invest Dermatol. 1991. PMID: 1705949 Free article.
The typical presentation of pediatric-onset mastocytosis consists of cutaneous manifestations: either a solitary mastocytoma, urticaria pigmentosa, or, less commonly, diffuse cutaneous mastocytosis. Particularly in infants, bullous eruptions may occur. ...
The typical presentation of pediatric-onset mastocytosis consists of cutaneous manifestations: either a solitary mastocytoma, urticaria pigm …
Mastocytosis: a comprehensive insight.
VAN Gysel D, DE Maeseneer H, Oranje AP. VAN Gysel D, et al. G Ital Dermatol Venereol. 2016 Aug;151(4):385-96. Epub 2016 Apr 12. G Ital Dermatol Venereol. 2016. PMID: 27070304 Review.
Measurement of serum tryptase is important in the diagnostic algorithm of pediatric mastocytosis. In children with tryptase <20 ng/mL, the diagnosis of cutaneous mastocytosis (CM) may be decided upon without bone marrow examination (BME), unless other signs of SM …
Measurement of serum tryptase is important in the diagnostic algorithm of pediatric mastocytosis. In children with tryptase <20 ng/mL, th …
Cutaneous Lesions of Mastocytosis: Mast Cell Count, Morphology, and Immunomolecular Phenotype.
Damman J, Diercks GFH, van Doorn MB, Pasmans SG, Hermans MAW. Damman J, et al. Am J Dermatopathol. 2023 Oct 1;45(10):697-703. doi: 10.1097/DAD.0000000000002474. Epub 2023 Jun 28. Am J Dermatopathol. 2023. PMID: 37378479
Pathologists are often challenged with skin biopsies with a question of cutaneous lesions of mastocytosis (CLM) including cutaneous mastocytosis, mastocytosis in the skin, or systemic mastocytosis. ...Noteworthy, the total number and percentage of MCs is significant …
Pathologists are often challenged with skin biopsies with a question of cutaneous lesions of mastocytosis (CLM) including cutaneous …
179 results