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168 results

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Quoted phrase not found in phrase index: "Grade 3 Larynx Mucositis or Stomatitis by Clinical Examination Classification, CTCAE"
Page 1
Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer.
Forastiere AA, Goepfert H, Maor M, Pajak TF, Weber R, Morrison W, Glisson B, Trotti A, Ridge JA, Chao C, Peters G, Lee DJ, Leaf A, Ensley J, Cooper J. Forastiere AA, et al. N Engl J Med. 2003 Nov 27;349(22):2091-8. doi: 10.1056/NEJMoa031317. N Engl J Med. 2003. PMID: 14645636 Free article. Clinical Trial.
The median follow-up period was 3.8 years. At two years, the proportion of patients who had an intact larynx after radiotherapy with concurrent cisplatin (88 percent) differed significantly from the proportions in the groups given induction chemotherapy followed by …
The median follow-up period was 3.8 years. At two years, the proportion of patients who had an intact larynx after radiotherap …
Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.
Lee NY, Ferris RL, Psyrri A, Haddad RI, Tahara M, Bourhis J, Harrington K, Chang PM, Lin JC, Razaq MA, Teixeira MM, Lövey J, Chamois J, Rueda A, Hu C, Dunn LA, Dvorkin MV, De Beukelaer S, Pavlov D, Thurm H, Cohen E. Lee NY, et al. Lancet Oncol. 2021 Apr;22(4):450-462. doi: 10.1016/S1470-2045(20)30737-3. Lancet Oncol. 2021. PMID: 33794205 Clinical Trial.
METHODS: In this randomised, double-blind, placebo-controlled, phase 3 study, patients were recruited from 196 hospitals and cancer treatment centres in 22 countries. ...Median progression-free survival was not reached (95% CI 16.9 months-not estimable) in the avelumab gro …
METHODS: In this randomised, double-blind, placebo-controlled, phase 3 study, patients were recruited from 196 hospitals and cancer t …
Mucosal Bridge Reconstruction: A Novel Approach for the Vocal Fold Mucosal Bridge.
Başer E, Denizoğlu İİ. Başer E, et al. Ann Otol Rhinol Laryngol. 2022 Nov;131(11):1281-1286. doi: 10.1177/00034894211053272. Epub 2022 Jan 5. Ann Otol Rhinol Laryngol. 2022. PMID: 34984939
METHODS: Between January 2016 and February 2020, 5 patients who applied to the voice clinic due to dysphonia and were diagnosed with MB via laryngostroboscopic examination and direct laryngoscopy under general anesthesia were included in the study. ...Mean postoperative fo …
METHODS: Between January 2016 and February 2020, 5 patients who applied to the voice clinic due to dysphonia and were diagnosed with MB via …
Appendiceal goblet cell carcinomas have poor survival despite completion surgery.
Alabraba E, Pritchard DM, Griffin R, Diaz-Nieto R, Banks M, Cuthbertson DJ, Fenwick S. Alabraba E, et al. Endocrine. 2021 Sep;73(3):734-744. doi: 10.1007/s12020-021-02727-9. Epub 2021 Apr 23. Endocrine. 2021. PMID: 33891259
Appendicectomy was the index surgery in 32 patients, 24 of whom subsequently underwent completion surgery at median 3 (range 1.3-13.3) months later. Histology from completion surgery showed residual disease in 8 patients: nodal disease (n = 2) or residual tum …
Appendicectomy was the index surgery in 32 patients, 24 of whom subsequently underwent completion surgery at median 3 (range 1.3 …
Treatment of head and neck cancers: issues for clinical pharmacists.
Scarpace SL, Brodzik FA, Mehdi S, Belgam R. Scarpace SL, et al. Pharmacotherapy. 2009 May;29(5):578-92. doi: 10.1592/phco.29.5.578. Pharmacotherapy. 2009. PMID: 19397465 Review.
Head and neck cancers are a heterogeneous group of diseases involving the oral cavity, pharyngeal tube, and larynx. Given the drug therapy options available, clinical pharmacists can play an important role in the care of this patient population. ...Induction therapy …
Head and neck cancers are a heterogeneous group of diseases involving the oral cavity, pharyngeal tube, and larynx. Given the drug th …
Clinical outcome and toxicity after simultaneous integrated boost IMRT in head and neck squamous cell cancer patients.
Dragan T, Beauvois S, Moreau M, Paesmans M, Vandekerkhove C, Cordier L, Van Gestel D. Dragan T, et al. Oral Oncol. 2019 Nov;98:132-140. doi: 10.1016/j.oraloncology.2019.09.012. Epub 2019 Oct 3. Oral Oncol. 2019. PMID: 31586895
MATERIAL AND METHODS: 106 patients with HNSCC of the oral cavity (OC), oropharynx (OP), larynx (L) and hypopharynx (HP), consecutively treated at our cancer center between 3/2012 and 3/2014 were retrospectively analyzed. ...The observed acute grade …
MATERIAL AND METHODS: 106 patients with HNSCC of the oral cavity (OC), oropharynx (OP), larynx (L) and hypopharynx (HP), consecutivel …
Endoscopic Resection and Mucosal Reconstitution With Epidermal Grafting: A Pilot Study in Idiopathic Subglottic Stenosis.
Davis RJ, Lina I, Motz K, Gelbard A, Lorenz RR, Sandhu GS, Hillel AT. Davis RJ, et al. Otolaryngol Head Neck Surg. 2022 May;166(5):917-926. doi: 10.1177/01945998211028163. Epub 2021 Jul 13. Otolaryngol Head Neck Surg. 2022. PMID: 34253069 Free PMC article.
Prespecified outcomes included (1) perioperative outcomes (Clavien-Dindo grade 4/5 complications, need for staged tracheostomy, hospital length of stay), (2) postoperative outcomes (peak expiratory flow rate [PEFR], need for subsequent airway surgery, tracheostomy at follo …
Prespecified outcomes included (1) perioperative outcomes (Clavien-Dindo grade 4/5 complications, need for staged tracheostomy, hospi …
Primary Sarcomas of the Larynx: A Clinicopathologic Study of 27 Cases.
Velez Torres JM, Martinez Duarte E, Diaz-Perez JA, Leibowitz J, Weed DT, Thomas G, Civantos FJ, Arnold DJ, Gomez-Fernandez C, Rosenberg AE. Velez Torres JM, et al. Head Neck Pathol. 2021 Sep;15(3):905-916. doi: 10.1007/s12105-021-01314-8. Epub 2021 Mar 8. Head Neck Pathol. 2021. PMID: 33686585 Free PMC article.
Primary sarcomas of the larynx are rare and are associated with diagnostic and treatment challenges. ...The cases included conventional chondrosarcoma (16), well-differentiated liposarcoma (2), clear cell chondrosarcoma (1), leiomyosarcoma (2), high grade myxofibros …
Primary sarcomas of the larynx are rare and are associated with diagnostic and treatment challenges. ...The cases included convention …
Clinicopathological spectrums and prognosis of primary appendiceal adenocarcinoma, goblet cell adenocarcinoma, and low-grade appendiceal mucinous neoplasms.
Chen I, Liu X, Kovar-Peltz S, Conrad SJ, Chen HH, Liao X. Chen I, et al. Pathology. 2023 Apr;55(3):375-382. doi: 10.1016/j.pathol.2022.08.004. Epub 2022 Oct 13. Pathology. 2023. PMID: 36454563
Primary appendiceal adenocarcinoma (APCA), goblet cell adenocarcinoma (GCA), and low/high-grade appendiceal mucinous neoplasms (LAMN/HAMN) are distinct entities with overlapping clinical presentation and histomorphology, leading to diagnostic challenges. ...KRAS mut …
Primary appendiceal adenocarcinoma (APCA), goblet cell adenocarcinoma (GCA), and low/high-grade appendiceal mucinous neoplasms (LAMN/ …
A multicenter phase II trial of paclitaxel, carboplatin, and cetuximab followed by chemoradiotherapy in patients with unresectable locally advanced squamous cell carcinoma of the head and neck.
Enokida T, Ogawa T, Homma A, Okami K, Minami S, Nakanome A, Shimizu Y, Maki D, Ueda Y, Fujisawa T, Motegi A, Ohkoshi A, Taguchi J, Ebisumoto K, Nomura S, Okano S, Tahara M. Enokida T, et al. Cancer Med. 2020 Mar;9(5):1671-1682. doi: 10.1002/cam4.2852. Epub 2020 Jan 13. Cancer Med. 2020. PMID: 31943834 Free PMC article. Clinical Trial.
Response rate was 88.6% by IC and 93.8% in the CRT phase. Three year overall survival was 83.5%. Main grade 3 toxicities included neutropenia (11.4%) and skin rash (5.7%) during IC; and oral mucositis (31.3%) and neutropenia (12.5%) during CRT. No g …
Response rate was 88.6% by IC and 93.8% in the CRT phase. Three year overall survival was 83.5%. Main grade 3 toxicities inclu …
168 results