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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1940 2
1942 1
1944 3
1945 2
1946 3
1947 10
1948 7
1949 6
1950 18
1951 10
1952 13
1953 11
1954 21
1955 13
1956 16
1957 14
1958 12
1959 10
1960 14
1961 11
1962 20
1963 13
1964 27
1965 35
1966 37
1967 41
1968 54
1969 43
1970 71
1971 54
1972 56
1973 51
1974 55
1975 69
1976 87
1977 88
1978 102
1979 112
1980 111
1981 138
1982 167
1983 198
1984 262
1985 261
1986 244
1987 273
1988 281
1989 316
1990 384
1991 526
1992 614
1993 685
1994 743
1995 852
1996 970
1997 1017
1998 1100
1999 1287
2000 1513
2001 1729
2002 2127
2003 2281
2004 2722
2005 3326
2006 3730
2007 4106
2008 4443
2009 4634
2010 5126
2011 5476
2012 5863
2013 6581
2014 6619
2015 6552
2016 6619
2017 6477
2018 6669
2019 6628
2020 7142
2021 7526
2022 7278
2023 6704
2024 2840

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121,314 results

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Page 1
Insulin Resistance: From Mechanisms to Therapeutic Strategies.
Lee SH, Park SY, Choi CS. Lee SH, et al. Diabetes Metab J. 2022 Jan;46(1):15-37. doi: 10.4093/dmj.2021.0280. Epub 2021 Dec 30. Diabetes Metab J. 2022. PMID: 34965646 Free PMC article. Review.
Although the underlying mechanism of insulin resistance is not fully understood, several credible theories have been proposed. ...In addition, we suggest potential therapeutic strategies for addressing insulin resistance....
Although the underlying mechanism of insulin resistance is not fully understood, several credible theories have been proposed. …
Insulin resistance: definition and consequences.
Lebovitz HE. Lebovitz HE. Exp Clin Endocrinol Diabetes. 2001;109 Suppl 2:S135-48. doi: 10.1055/s-2001-18576. Exp Clin Endocrinol Diabetes. 2001. PMID: 11460565 Review.
--Several mechanisms have been proposed as possible causes underlying the development of insulin resistance and the insulin resistance syndrome. These include: (1) genetic abnormalities of one or more proteins of the insulin action cascade (2) fetal ma …
--Several mechanisms have been proposed as possible causes underlying the development of insulin resistance and the insulin …
Insulin Resistance, Obesity and Lipotoxicity.
Yazıcı D, Sezer H. Yazıcı D, et al. Adv Exp Med Biol. 2017;960:277-304. doi: 10.1007/978-3-319-48382-5_12. Adv Exp Med Biol. 2017. PMID: 28585204 Review.
Mitochondrial dysfunction plays a role in the pathogenesis of insulin resistance. Endoplasmic reticulum stress, through mainly increased oxidative stress, also plays important role in the etiology of insulin resistance, especially seen in non-alcoholic …
Mitochondrial dysfunction plays a role in the pathogenesis of insulin resistance. Endoplasmic reticulum stress, through mainly …
Insulin Resistance.
Freeman AM, Acevedo LA, Pennings N. Freeman AM, et al. 2023 Aug 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29939616 Free Books & Documents.
The clinical definition of insulin resistance remains elusive, as there is no generally accepted test for insulin resistance. Clinically, insulin resistance is recognized via the metabolic consequences associated with insulin re …
The clinical definition of insulin resistance remains elusive, as there is no generally accepted test for insulin re …
Exercise and Insulin Resistance.
Whillier S. Whillier S. Adv Exp Med Biol. 2020;1228:137-150. doi: 10.1007/978-981-15-1792-1_9. Adv Exp Med Biol. 2020. PMID: 32342455 Review.
During exercise glucose uptake can occur independently of insulin regulation, and hence research into the effects of exercise on insulin resistance must be clearly defined to reflect whether glucose uptake has been enhanced as a result of the utilisation of these in …
During exercise glucose uptake can occur independently of insulin regulation, and hence research into the effects of exercise on insulin …
Insulin and insulin resistance.
Wilcox G. Wilcox G. Clin Biochem Rev. 2005 May;26(2):19-39. Clin Biochem Rev. 2005. PMID: 16278749 Free PMC article.
This review provides an overview of insulin, its history, structure, synthesis, secretion, actions and interactions followed by a discussion of insulin resistance and its associated clinical manifestations. Specific areas of focus include the actions of insulin and …
This review provides an overview of insulin, its history, structure, synthesis, secretion, actions and interactions followed by a discussion …
New classification and diagnostic criteria for insulin resistance syndrome.
Ogawa W, Araki E, Ishigaki Y, Hirota Y, Maegawa H, Yamauchi T, Yorifuji T, Katagiri H. Ogawa W, et al. Endocr J. 2022 Feb 28;69(2):107-113. doi: 10.1507/endocrj.EJ21-0725. Epub 2022 Feb 1. Endocr J. 2022. PMID: 35110500 Free article.
This report of a working group established by the Japan Diabetes Society proposes a new classification and diagnostic criteria for insulin resistance syndrome. Insulin resistance syndrome is defined as a condition characterized by severe attenuation of …
This report of a working group established by the Japan Diabetes Society proposes a new classification and diagnostic criteria for insuli …
Biomarkers of insulin sensitivity and insulin resistance: Past, present and future.
Park SE, Park CY, Sweeney G. Park SE, et al. Crit Rev Clin Lab Sci. 2015;52(4):180-90. doi: 10.3109/10408363.2015.1023429. Epub 2015 Jun 4. Crit Rev Clin Lab Sci. 2015. PMID: 26042993 Review.
Accurate diagnostic parameters reflective of insulin resistance are essential. Longstanding tests for fasting blood glucose and HbA1c are useful and although the hyperinsulinemic euglycemic clamp remains a "gold standard" for accurately determining insulin …
Accurate diagnostic parameters reflective of insulin resistance are essential. Longstanding tests for fasting blood glucose an …
Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches.
Ding PF, Zhang HS, Wang J, Gao YY, Mao JN, Hang CH, Li W. Ding PF, et al. Front Endocrinol (Lausanne). 2022 Dec 15;13:1092431. doi: 10.3389/fendo.2022.1092431. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36589857 Free PMC article. Review.
The pathological condition of insulin resistance prevents the neuroprotective effects of insulin. ...We explored the association between insulin resistance and the primary mechanisms of brain injury in ischemic stroke (inflammation, oxidative stress, a …
The pathological condition of insulin resistance prevents the neuroprotective effects of insulin. ...We explored the associati …
Obesity, Bioactive Lipids, and Adipose Tissue Inflammation in Insulin Resistance.
Kojta I, Chacińska M, Błachnio-Zabielska A. Kojta I, et al. Nutrients. 2020 May 3;12(5):1305. doi: 10.3390/nu12051305. Nutrients. 2020. PMID: 32375231 Free PMC article. Review.
Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. The exact mechanism by which adipose tissue induces insulin resistance is still unclear. ...Although studies have revealed that inflammation caused by excessi …
Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. The exact mechanism by which adi …
121,314 results
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