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59 results

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Page 1
Pediatric focal epilepsy syndromes.
Sánchez Fernández I, Loddenkemper T. Sánchez Fernández I, et al. J Clin Neurophysiol. 2012 Oct;29(5):425-40. doi: 10.1097/WNP.0b013e31826bd943. J Clin Neurophysiol. 2012. PMID: 23027100 Review.
They share major common characteristics: the appearance and resolution of electroclinical features are age related, there is a strong genetic predisposition, the clinical course is often mild with infrequent and easy to control seizures, interictal epileptiform a …
They share major common characteristics: the appearance and resolution of electroclinical features are age related, there is a strong geneti …
Seizure forecasting: Where do we stand?
Andrzejak RG, Zaveri HP, Schulze-Bonhage A, Leguia MG, Stacey WC, Richardson MP, Kuhlmann L, Lehnertz K. Andrzejak RG, et al. Epilepsia. 2023 Dec;64 Suppl 3(Suppl 3):S62-S71. doi: 10.1111/epi.17546. Epub 2023 Mar 8. Epilepsia. 2023. PMID: 36780237 Free PMC article.
Most prominently, this has allowed the confirmation of the long-suspected cyclical nature of interictal epileptiform activity, seizure risk, and seizures. The timescales cover daily, multi-day, and yearly cycles. ...Considering epilepsy as a large-scale netwo …
Most prominently, this has allowed the confirmation of the long-suspected cyclical nature of interictal epileptiform activi …
Seizure Cycles under Pharmacotherapy.
Friedrichs-Maeder C, Proix T, Tcheng TK, Skarpaas T, Rao VR, Baud MO. Friedrichs-Maeder C, et al. Ann Neurol. 2024 Apr;95(4):743-753. doi: 10.1002/ana.26878. Epub 2024 Feb 20. Ann Neurol. 2024. PMID: 38379195
OBJECTIVE: This study was undertaken to determine the effects of antiseizure medications (ASMs) on multidien (multiday) cycles of interictal epileptiform activity (IEA) and seizures and evaluate their potential clinical significance. ...INTERPRETATION: In thi …
OBJECTIVE: This study was undertaken to determine the effects of antiseizure medications (ASMs) on multidien (multiday) cycles of interic …
Possible Clinical and Pharmacogenetic Predictors of the Efficacy and Safety of Carbamazepine in Post-COVID-19 Depression.
Vaiman E, Gayduk A, Strelnik A, Smirnova D, Davydkin I, Fedyashov I, Cumming P, Shnayder N, Nasyrova R. Vaiman E, et al. Psychiatr Danub. 2022 Sep;34(Suppl 8):31-37. Psychiatr Danub. 2022. PMID: 36170698 Free article. Review.
The aim of the review was to investigate pharmacogenetic predictors of safety and efficacy of CMZ in patients with depressive symptoms of Long COVID during the post-infection period. ...CONCLUSIONS: The choice of antidepressant treatment for patients with Long COVID is fra …
The aim of the review was to investigate pharmacogenetic predictors of safety and efficacy of CMZ in patients with depressive symptom …
Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers.
Hillebrand A, Holmes N, Sijsma N, O'Neill GC, Tierney TM, Liberton N, Stam AH, van Klink N, Stam CJ, Bowtell R, Brookes MJ, Barnes GR. Hillebrand A, et al. Sci Rep. 2023 Mar 21;13(1):4623. doi: 10.1038/s41598-023-31111-y. Sci Rep. 2023. PMID: 36944674 Free PMC article.
Importantly, the wearability of OPMs enabled the recording of seizure activity in a patient with hyperkinetic movements during the seizure. The observed ictal onset and semiology were in agreement with previous video- and stereo-EEG recordings. ...
Importantly, the wearability of OPMs enabled the recording of seizure activity in a patient with hyperkinetic movements during the seizure. …
Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders.
Milovanovic M, Radivojevic V, Radosavljev-Kircanski J, Grujicic R, Toskovic O, Aleksić-Hil O, Pejovic-Milovancevic M. Milovanovic M, et al. Epilepsy Behav. 2019 Mar;92:45-52. doi: 10.1016/j.yebeh.2018.12.011. Epub 2019 Jan 3. Epilepsy Behav. 2019. PMID: 30611007

There was a slight tendency of the VABS-II motor skills score to be higher in the group of patients with autism without clinical diagnosis of epilepsy and without subclinical epileptiform discharges (p < 0.05) in comparison with the two other groups. According to this t

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There was a slight tendency of the VABS-II motor skills score to be higher in the group of patients with autism without clinical diag …
Alterations of Neuronal Dynamics as a Mechanism for Cognitive Impairment in Epilepsy.
Lenck-Santini PP, Sakkaki S. Lenck-Santini PP, et al. Curr Top Behav Neurosci. 2022;55:65-106. doi: 10.1007/7854_2020_193. Curr Top Behav Neurosci. 2022. PMID: 33454922 Review.
These alterations, caused by the underlying etiologies of epilepsy syndromes, are observed in both animal models and patients in the form of abnormal oscillation patterns in unit firing, local field potentials, and electroencephalogram (EEG). Evidence suggests that such me …
These alterations, caused by the underlying etiologies of epilepsy syndromes, are observed in both animal models and patients in the …
An update on the seizures beget seizures theory.
Jiruska P, Freestone D, Gnatkovsky V, Wang Y. Jiruska P, et al. Epilepsia. 2023 Dec;64 Suppl 3:S13-S24. doi: 10.1111/epi.17721. Epub 2023 Aug 2. Epilepsia. 2023. PMID: 37466948
We critically review the existing data and observations on the consequences of recurrent seizures on brain networks and highlight a range of factors that speak for and against the theory. ...Epilepsy worsening can be attributed to the various forms of interictal …
We critically review the existing data and observations on the consequences of recurrent seizures on brain networks and highlight a r …
Language organization and reorganization in epilepsy.
Hamberger MJ, Cole J. Hamberger MJ, et al. Neuropsychol Rev. 2011 Sep;21(3):240-51. doi: 10.1007/s11065-011-9180-z. Epub 2011 Aug 13. Neuropsychol Rev. 2011. PMID: 21842185 Free PMC article. Review.
Investigators have used these techniques to explore the influence of unique clinical features inherent in epilepsy that might contribute to the reorganization of language, such as location of seizure onset, age of seizure onset, and extent of interictal epileptiform …
Investigators have used these techniques to explore the influence of unique clinical features inherent in epilepsy that might contribute to …
Neocortical temporal lobe epilepsy.
Kennedy JD, Schuele SU. Kennedy JD, et al. J Clin Neurophysiol. 2012 Oct;29(5):366-70. doi: 10.1097/WNP.0b013e31826bd78b. J Clin Neurophysiol. 2012. PMID: 23027092 Review.
Neurophysiologic findings in NTLE are typically a predominance of lateral temporal interictal epileptiform activity (IEA) and an ictal onset pattern consisting of irregular, hemispheric delta slowing. ...
Neurophysiologic findings in NTLE are typically a predominance of lateral temporal interictal epileptiform activity (IE …
59 results