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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1951 2
1952 3
1953 2
1954 4
1955 1
1956 2
1957 3
1958 4
1959 1
1961 3
1963 2
1964 2
1965 6
1966 10
1967 23
1968 20
1969 43
1970 25
1971 33
1972 28
1973 40
1974 32
1975 55
1976 47
1977 51
1978 39
1979 54
1980 47
1981 43
1982 53
1983 62
1984 59
1985 55
1986 48
1987 85
1988 58
1989 73
1990 85
1991 88
1992 60
1993 66
1994 89
1995 79
1996 88
1997 90
1998 87
1999 91
2000 109
2001 104
2002 115
2003 155
2004 110
2005 117
2006 157
2007 229
2008 159
2009 212
2010 169
2011 188
2012 213
2013 201
2014 211
2015 202
2016 191
2017 187
2018 228
2019 227
2020 261
2021 299
2022 281
2023 211
2024 84

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5,982 results

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Page 1
Update on the Management of Infectious Keratitis.
Austin A, Lietman T, Rose-Nussbaumer J. Austin A, et al. Ophthalmology. 2017 Nov;124(11):1678-1689. doi: 10.1016/j.ophtha.2017.05.012. Epub 2017 Sep 21. Ophthalmology. 2017. PMID: 28942073 Free PMC article. Review.
The randomized controlled Mycotic Ulcer Treatment Trial (MUTT) I showed a benefit of topical natamycin over topical voriconazole for fungal ulcers, particularly among those caused by Fusarium. ...Future strategies to reduce the morbidity associated with infectious …
The randomized controlled Mycotic Ulcer Treatment Trial (MUTT) I showed a benefit of topical natamycin over topical voriconazo …
Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes.
Sharma N, Bagga B, Singhal D, Nagpal R, Kate A, Saluja G, Maharana PK. Sharma N, et al. Ocul Surf. 2022 Apr;24:22-30. doi: 10.1016/j.jtos.2021.12.001. Epub 2021 Dec 13. Ocul Surf. 2022. PMID: 34915188 Review.
Infectious keratitis is a significant cause of corneal blindness worldwide. Although less prevalent in the developed world, cases of fungal keratitis account for almost half of all keratitis cases, occurring in the developing countries. ...The advent of rapid …
Infectious keratitis is a significant cause of corneal blindness worldwide. Although less prevalent in the developed world, cases of …
Conjunctivitis in dupilumab clinical trials.
Akinlade B, Guttman-Yassky E, de Bruin-Weller M, Simpson EL, Blauvelt A, Cork MJ, Prens E, Asbell P, Akpek E, Corren J, Bachert C, Hirano I, Weyne J, Korotzer A, Chen Z, Hultsch T, Zhu X, Davis JD, Mannent L, Hamilton JD, Teper A, Staudinger H, Rizova E, Pirozzi G, Graham NMH, Shumel B, Ardeleanu M, Wollenberg A. Akinlade B, et al. Br J Dermatol. 2019 Sep;181(3):459-473. doi: 10.1111/bjd.17869. Epub 2019 May 7. Br J Dermatol. 2019. PMID: 30851191 Free PMC article.
OBJECTIVES: To characterize further the occurrence and risk factors of conjunctivitis in dupilumab clinical trials. METHODS: We evaluated randomized placebo-controlled trials of dupilumab in AD (n = 2629), asthma (n = 2876), chronic rhinosinusitis with nasal polyps …
OBJECTIVES: To characterize further the occurrence and risk factors of conjunctivitis in dupilumab clinical trials. METHODS: We evalu …
Antibiotics versus placebo for acute bacterial conjunctivitis.
Chen YY, Liu SH, Nurmatov U, van Schayck OC, Kuo IC. Chen YY, et al. Cochrane Database Syst Rev. 2023 Mar 13;3(3):CD001211. doi: 10.1002/14651858.CD001211.pub4. Cochrane Database Syst Rev. 2023. PMID: 36912752 Free PMC article. Review.
A total of 8805 participants were randomized. All treatments were topical in the form of drops or ointment. ...Based on intention-to-treat (ITT) population, antibiotics likely improved clinical cure (resolution of clinical symptoms or signs) by 26% (RR 1.26, …
A total of 8805 participants were randomized. All treatments were topical in the form of drops or ointment. ...Based on intention-to- …
Thygeson's superficial punctate keratitis.
Mandal N, Yeung SN, Tadrous C, Iovieno A. Mandal N, et al. Graefes Arch Clin Exp Ophthalmol. 2022 Jun;260(6):1837-1841. doi: 10.1007/s00417-022-05617-6. Epub 2022 Mar 12. Graefes Arch Clin Exp Ophthalmol. 2022. PMID: 35286434 Review.
METHOD: A literature search was done on PubMed using keywords including Thygeson's superficial punctate keratitis, punctate keratitis, etiology, management, and treatment. ...Mechanisms proposed including viral infection, immune-mediated, and immune responses to vir …
METHOD: A literature search was done on PubMed using keywords including Thygeson's superficial punctate keratitis, punctate kerati …
In vivo CRISPR gene editing in patients with herpetic stromal keratitis.
Wei A, Yin D, Zhai Z, Ling S, Le H, Tian L, Xu J, Paludan SR, Cai Y, Hong J. Wei A, et al. Mol Ther. 2023 Nov 1;31(11):3163-3175. doi: 10.1016/j.ymthe.2023.08.021. Epub 2023 Aug 31. Mol Ther. 2023. PMID: 37658603 Clinical Trial.
In vivo CRISPR gene therapy holds large clinical potential, but the safety and efficacy remain largely unknown. Here, we injected a single dose of herpes simplex virus 1 (HSV-1)-targeting CRISPR formulation in the cornea of three patients with severe refractory herpetic st …
In vivo CRISPR gene therapy holds large clinical potential, but the safety and efficacy remain largely unknown. Here, we injected a s …
The Orphan Drug for Acanthamoeba Keratitis (ODAK) Trial: PHMB 0.08% (Polihexanide) and Placebo versus PHMB 0.02% and Propamidine 0.1.
Dart JKG, Papa V, Rama P, Knutsson KA, Ahmad S, Hau S, Sanchez S, Franch A, Birattari F, Leon P, Fasolo A, Kominek EM, Jadczyk-Sorek K, Carley F, Hossain P, Minassian DC. Dart JKG, et al. Ophthalmology. 2024 Mar;131(3):277-287. doi: 10.1016/j.ophtha.2023.09.031. Epub 2023 Oct 5. Ophthalmology. 2024. PMID: 37802392 Free article. Clinical Trial.
METHODS: Principal inclusion criteria were 12 years of age or older and in vivo confocal microscopy with clinical findings consistent with AK. Also included were participants with concurrent bacterial keratitis who were using topical steroids and antiviral and antif …
METHODS: Principal inclusion criteria were 12 years of age or older and in vivo confocal microscopy with clinical findings consistent …
Cross-linking for microbial keratitis.
Chan TC, Agarwal T, Vajpayee RB, Jhanji V. Chan TC, et al. Curr Opin Ophthalmol. 2016 Jul;27(4):348-52. doi: 10.1097/ICU.0000000000000271. Curr Opin Ophthalmol. 2016. PMID: 27093100 Review.
SUMMARY: CXL appears to be a promising adjunctive treatment in selective cases of mild to moderate bacterial keratitis. Its efficacy in fungal and amoebic keratitis is questionable. Treatment protocols in microbial keratitis need to be individualized. Long-te …
SUMMARY: CXL appears to be a promising adjunctive treatment in selective cases of mild to moderate bacterial keratitis. Its efficacy …
20 years since the Herpetic Eye Disease Study: Lessons, developments and applications to clinical practice.
Arshad S, Petsoglou C, Lee T, Al-Tamimi A, Carnt NA. Arshad S, et al. Clin Exp Optom. 2021 Apr;104(3):396-405. doi: 10.1080/08164622.2021.1877531. Epub 2021 Feb 24. Clin Exp Optom. 2021. PMID: 33689622 Free article.
The Herpetic Eye Disease Study (HEDS) was a landmark series of randomised controlled trials in the 1990s that set the benchmark for evidence-based treatment guidelines for anterior eye herpetic disease. ...However, many of the principles of the HEDS study remain rightly en …
The Herpetic Eye Disease Study (HEDS) was a landmark series of randomised controlled trials in the 1990s that set the benchmark for e …
Steroids in the Management of Infectious Keratitis.
Keenan JD. Keenan JD. Cornea. 2023 Nov 1;42(11):1333-1339. doi: 10.1097/ICO.0000000000003340. Epub 2023 Jul 4. Cornea. 2023. PMID: 38112645 Review.
No randomized trials have assessed the safety and effectiveness of steroids for fungal or acanthamoeba keratitis. ...CONCLUSIONS: Topical corticosteroids, when used as an adjunct to antimicrobial therapy, may be beneficial if the antimicrobial being used can effecti …
No randomized trials have assessed the safety and effectiveness of steroids for fungal or acanthamoeba keratitis. ...CONCLUSIO …
5,982 results