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Platinum-Fluoropyrimidine and Paclitaxel-Based Chemotherapy in the Treatment of Advanced Anal Cancer Patients.
Sclafani F, Morano F, Cunningham D, Baratelli C, Kalaitzaki E, Watkins D, Starling N, Chau I, Rao S. Sclafani F, et al. Oncologist. 2017 Apr;22(4):402-408. doi: 10.1634/theoncologist.2016-0241. Epub 2017 Feb 16. Oncologist. 2017. PMID: 28209745 Free PMC article.
Five-year OS in the overall population was 15% (95% CI, 7.0%-25.0%). Age 65 years and liver metastases were predictive of better PFS (hazard ratio [HR], 0.39; 95% CI, 0.16-0.97; p = .04) and worse OS (HR, 2.25; 95% CI, 1.25-4.03; p = .01), respectively. ...Clinical trials …
Five-year OS in the overall population was 15% (95% CI, 7.0%-25.0%). Age 65 years and liver metastases were predictive of better PFS …
Does gap-free intensity modulated chemoradiation therapy provide a greater clinical benefit than 3D conformal chemoradiation in patients with anal cancer?
Dewas CV, Maingon P, Dalban C, Petitfils A, Peignaux K, Truc G, Martin E, Khoury C, Dewas S, Créhange G. Dewas CV, et al. Radiat Oncol. 2012 Nov 29;7:201. doi: 10.1186/1748-717X-7-201. Radiat Oncol. 2012. PMID: 23190693 Free PMC article.
IMRT makes it possible to remove the gap, but with no impact on the prognosis. Nonetheless, a longer follow-up is essential to determine whether or not IMRT has an impact on late toxicity, local control and survival compared with conventional 3D-CRT....
IMRT makes it possible to remove the gap, but with no impact on the prognosis. Nonetheless, a longer follow-up is essential to determ …