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Page 1
The pathology of large granular lymphocyte leukemia.
Agnarsson BA, Loughran TP Jr, Starkebaum G, Kadin ME. Agnarsson BA, et al. Hum Pathol. 1989 Jul;20(7):643-51. doi: 10.1016/0046-8177(89)90151-2. Hum Pathol. 1989. PMID: 2661408
The bone marrow biopsies contained nonparatrabecular lymphoid infiltrates that were nodular or diffuse and interstitial. Plasmacytosis was found and in two cases there was myeloid maturation arrest. The liver biopsies contained sinusoidal and portal infiltrat …
The bone marrow biopsies contained nonparatrabecular lymphoid infiltrates that were nodular or diffuse and interstitial. Plasmacytosis was f …
Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia.
Druhan LJ, Ai J, Massullo P, Kindwall-Keller T, Ranalli MA, Avalos BR. Druhan LJ, et al. Blood. 2005 Jan 15;105(2):584-91. doi: 10.1182/blood-2004-07-2613. Epub 2004 Sep 7. Blood. 2005. PMID: 15353486 Free article.
Severe congenital neutropenia (SCN) is a rare disease diagnosed at or soon after birth, characterized by a myeloid maturation arrest in the bone marrow, ineffective neutrophil production, and recurrent infections. ...
Severe congenital neutropenia (SCN) is a rare disease diagnosed at or soon after birth, characterized by a myeloid maturation
Hepatic hemangioendothelioma in an infant with severe congenital neutropenia.
Dinand V, Yadav SP, Bellanné-Chantelot C, Jain S, Bhargava M, Sachdeva A. Dinand V, et al. J Pediatr Hematol Oncol. 2012 May;34(4):298-300. doi: 10.1097/MPH.0b013e318249a4dc. J Pediatr Hematol Oncol. 2012. PMID: 22510773
Postoperatively, severe neutropenia was noted. Bone marrow examination showed myeloid maturation arrest, diagnostic of SCN. Mutation analysis for the neutrophil elastase gene identified a novel heterozygous de novo ELANE missense mutation in exon 2 (c.215T&gt …
Postoperatively, severe neutropenia was noted. Bone marrow examination showed myeloid maturation arrest, diagnostic of …
Severe congenital neutropenia in 2 siblings of consanguineous parents. The role of HAX1 deficiency.
Mamishi S, Esfahani SA, Parvaneh N, Diestelhorst J, Rezaei N. Mamishi S, et al. J Investig Allergol Clin Immunol. 2009;19(6):500-3. J Investig Allergol Clin Immunol. 2009. PMID: 20128427 Free article.
A bone marrow biopsy, performed to determine the cause of their persistent severe neutropenia, revealed myeloid maturation arrest; thus confirming the diagnosis of SCN. Granulocyte colony-stimulating factor and prophylactic antibiotics were started. ...
A bone marrow biopsy, performed to determine the cause of their persistent severe neutropenia, revealed myeloid maturation