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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 2
1975 2
1976 2
1977 1
1978 2
1979 1
1980 2
1981 1
1983 2
1984 1
1985 7
1986 2
1987 2
1988 4
1989 2
1990 5
1991 2
1993 3
1994 8
1995 6
1996 1
1997 3
1998 3
1999 3
2000 4
2001 6
2002 6
2003 12
2004 8
2005 18
2006 13
2007 12
2008 14
2009 6
2010 12
2011 20
2012 38
2013 43
2014 44
2015 53
2016 48
2017 53
2018 56
2019 77
2020 62
2021 35
2022 41
2023 21
2024 5

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Search Results

644 results

Results by year

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Page 1
Parkinson's disease.
Bloem BR, Okun MS, Klein C. Bloem BR, et al. Lancet. 2021 Jun 12;397(10291):2284-2303. doi: 10.1016/S0140-6736(21)00218-X. Epub 2021 Apr 10. Lancet. 2021. PMID: 33848468 Review.
Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. ...Clinically manifest Parkinson's disease is preceded by a potentially long prodromal period. Presently, establishment of prodromal symptoms has …
Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. ...Clinically manif …
Schizophrenia-An Overview.
McCutcheon RA, Reis Marques T, Howes OD. McCutcheon RA, et al. JAMA Psychiatry. 2020 Feb 1;77(2):201-210. doi: 10.1001/jamapsychiatry.2019.3360. JAMA Psychiatry. 2020. PMID: 31664453 Review.
This educational review is integrated with a clinical case to highlight how recent research findings can inform clinical understanding. OBSERVATIONS: The first theme considered is the role of early-life environmental and genetic risk factors in altering neurodevelop …
This educational review is integrated with a clinical case to highlight how recent research findings can inform clinical under …
Shingrix for Herpes Zoster: A Review.
Shah RA, Limmer AL, Nwannunu CE, Patel RR, Mui UN, Tyring SK. Shah RA, et al. Skin Therapy Lett. 2019 Jul;24(4):5-7. Skin Therapy Lett. 2019. PMID: 31339679 Free article. Review.
HZ presents as a painful, vesicular rash distributed in a unilateral and dermatomal pattern along dorsal root or cranial nerve ganglia. The rash often presents with prodromal symptoms and progresses to include clear vesicular clusters, evolving through stages of pus …
HZ presents as a painful, vesicular rash distributed in a unilateral and dermatomal pattern along dorsal root or cranial nerve ganglia. The …
Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype.
Vermunt L, Sikkes SAM, van den Hout A, Handels R, Bos I, van der Flier WM, Kern S, Ousset PJ, Maruff P, Skoog I, Verhey FRJ, Freund-Levi Y, Tsolaki M, Wallin ÅK, Olde Rikkert M, Soininen H, Spiru L, Zetterberg H, Blennow K, Scheltens P, Muniz-Terrera G, Visser PJ; Alzheimer Disease Neuroimaging Initiative; AIBL Research Group; ICTUS/DSA study groups. Vermunt L, et al. Alzheimers Dement. 2019 Jul;15(7):888-898. doi: 10.1016/j.jalz.2019.04.001. Epub 2019 Jun 1. Alzheimers Dement. 2019. PMID: 31164314 Free PMC article.
For individuals presenting with preclinical AD, age 70, the estimated preclinical AD duration was 10 years, prodromal AD 4 years, and dementia 6 years. Male sex, clinical setting, APOE epsilon4 allele carriership, and abnormal cerebrospinal fluid tau were associated with a …
For individuals presenting with preclinical AD, age 70, the estimated preclinical AD duration was 10 years, prodromal AD 4 years, and dement …
Progression of clinical markers in prodromal Parkinson's disease and dementia with Lewy bodies: a multicentre study.
Joza S, Hu MT, Jung KY, Kunz D, Stefani A, Dušek P, Terzaghi M, Arnaldi D, Videnovic A, Schiess MC, Hermann W, Lee JY, Ferini-Strambi L, Lewis SJG, Leclair-Visonneau L, Oertel WH, Antelmi E, Sixel-Döring F, Cochen De Cock V, Liguori C, Liu J, Provini F, Puligheddu M, Nicoletti A, Bassetti CLA, Bušková J, Dauvilliers Y, Ferri R, Montplaisir JY, Lawton M, Kim HJ, Bes F, Högl B, Šonka K, Fiamingo G, Mattioli P, Lavadia ML, Suescun J, Woo KA, Marelli S, Martens KE, Janzen A, Plazzi G, Mollenhauer B, Fernandes M, Li Y, Cortelli P, Figorilli M, Cicero CE, Schaefer C, Guiraud L, Lanza G, Gagnon JF, Sunwoo JS, Ibrahim A, Girtler N, Trenkwalder C, Baldelli L, Pelletier A, Postuma RB; International REM Sleep Behavior Disorder Study Group. Joza S, et al. Brain. 2023 Aug 1;146(8):3258-3272. doi: 10.1093/brain/awad072. Brain. 2023. PMID: 36881989 Free article.
Among these, idiopathic REM sleep behaviour disorder is a powerful early predictor of eventual phenoconversion, and therefore represents a critical opportunity to intervene with neuroprotective therapy. To inform the design of randomized trials, it is essential to study th …
Among these, idiopathic REM sleep behaviour disorder is a powerful early predictor of eventual phenoconversion, and therefore represents a c …
36-month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease.
Soininen H, Solomon A, Visser PJ, Hendrix SB, Blennow K, Kivipelto M, Hartmann T; LipiDiDiet clinical study group. Soininen H, et al. Alzheimers Dement. 2021 Jan;17(1):29-40. doi: 10.1002/alz.12172. Epub 2020 Sep 13. Alzheimers Dement. 2021. PMID: 32920957 Free PMC article. Clinical Trial.
Based on previous results we hypothesized that benefits increase with long-term intervention. METHODS: In this randomized, double-blind, placebo-controlled trial, 311 people with prodromal AD were recruited using the International Working Group-1 criteria and assign …
Based on previous results we hypothesized that benefits increase with long-term intervention. METHODS: In this randomized, double-bli …
Myo-inositol plus selenium supplementation restores euthyroid state in Hashimoto's patients with subclinical hypothyroidism.
Nordio M, Basciani S. Nordio M, et al. Eur Rev Med Pharmacol Sci. 2017 Jun;21(2 Suppl):51-59. Eur Rev Med Pharmacol Sci. 2017. PMID: 28724185 Free article. Clinical Trial.
OBJECTIVE: Clinical evidence suggests that oral supplementation with myo-inositol (MI) and selenium (Se) is useful in the treatment of autoimmune thyroiditis. ...PATIENTS AND METHODS: A total of 168 patients with Hashimoto's thyroiditis (HT) having Thyroid Stimulating Horm …
OBJECTIVE: Clinical evidence suggests that oral supplementation with myo-inositol (MI) and selenium (Se) is useful in the treatment o …
Narrative review of the advances in the pharmacotherapeutic management of juvenile-onset schizophrenia.
Crump CJ, Good ME, Abuelazm H, El-Mallakh RS. Crump CJ, et al. Expert Opin Pharmacother. 2023 Jun;24(9):1039-1052. doi: 10.1080/14656566.2023.2208269. Epub 2023 May 1. Expert Opin Pharmacother. 2023. PMID: 37102321 Review.
INTRODUCTION: Schizophrenia usually begins with prodromal symptoms in adolescence. In 39% of patients, onset of psychotic symptoms occurs prior to age 19. ...
INTRODUCTION: Schizophrenia usually begins with prodromal symptoms in adolescence. In 39% of patients, onset of psychotic symp …
A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.
Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, Santarelli L, Fontoura P; SCarlet RoAD Investigators. Ostrowitzki S, et al. Alzheimers Res Ther. 2017 Dec 8;9(1):95. doi: 10.1186/s13195-017-0318-y. Alzheimers Res Ther. 2017. PMID: 29221491 Free PMC article. Clinical Trial.
Exploratory analyses suggested a dose-dependent drug effect on clinical and biomarker endpoints. CONCLUSIONS: The study was stopped early for futility, but dose-dependent effects observed in exploratory analyses on select clinical and biomarker endpoints suggest tha …
Exploratory analyses suggested a dose-dependent drug effect on clinical and biomarker endpoints. CONCLUSIONS: The study was stopped e …
644 results