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Year Number of Results
1974 1
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1978 2
1979 3
1981 1
1983 1
1984 1
1986 2
1987 2
1989 1
1990 3
1991 2
1992 3
1993 2
1994 2
1995 3
1998 2
1999 6
2001 9
2003 6
2004 5
2005 6
2007 1
2008 13
2009 6
2010 6
2011 7
2012 10
2013 9
2014 15
2015 14
2016 14
2017 25
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2019 11
2020 17
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2023 18
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236 results

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Quoted phrase not found in phrase index: "Squamous cell bile duct carcinoma"
Page 1
Intrahepatic Cholangiocarcinoma.
El-Diwany R, Pawlik TM, Ejaz A. El-Diwany R, et al. Surg Oncol Clin N Am. 2019 Oct;28(4):587-599. doi: 10.1016/j.soc.2019.06.002. Surg Oncol Clin N Am. 2019. PMID: 31472907 Review.
Intrahepatic cholangiocarcinoma (ICC) arises from the epithelial cells of the intrahepatic and extrahepatic bile ducts and occurs proximal to the segmental biliary ducts. ...
Intrahepatic cholangiocarcinoma (ICC) arises from the epithelial cells of the intrahepatic and extrahepatic bile ducts …
Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis.
Sia D, Villanueva A, Friedman SL, Llovet JM. Sia D, et al. Gastroenterology. 2017 Mar;152(4):745-761. doi: 10.1053/j.gastro.2016.11.048. Epub 2016 Dec 30. Gastroenterology. 2017. PMID: 28043904 Free article. Review.
Molecular studies have identified adult hepatocytes as the cell of origin. These cells have been proposed to transform directly into HCC cells (via a sequence of genetic alterations), to dedifferentiate into hepatocyte precursor cells (which then becom …
Molecular studies have identified adult hepatocytes as the cell of origin. These cells have been proposed to transform directl …
NOTCH-YAP1/TEAD-DNMT1 Axis Drives Hepatocyte Reprogramming Into Intrahepatic Cholangiocarcinoma.
Hu S, Molina L, Tao J, Liu S, Hassan M, Singh S, Poddar M, Bell A, Sia D, Oertel M, Raeman R, Nejak-Bowen K, Singhi A, Luo J, Monga SP, Ko S. Hu S, et al. Gastroenterology. 2022 Aug;163(2):449-465. doi: 10.1053/j.gastro.2022.05.007. Epub 2022 May 10. Gastroenterology. 2022. PMID: 35550144 Free PMC article.
Yap1 or TEAD inhibition, but not Sox9 deletion, impairs HC-to-biliary epithelial cell (BEC) reprogramming. DNMT1 was discovered as a novel downstream effector of YAP1-TEAD complex that directs HC-to-BEC/ICC fate switch through the repression of HC-specific genes reg …
Yap1 or TEAD inhibition, but not Sox9 deletion, impairs HC-to-biliary epithelial cell (BEC) reprogramming. DNMT1 was discovere …
Targeting cholangiocarcinoma.
Mertens JC, Rizvi S, Gores GJ. Mertens JC, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1454-1460. doi: 10.1016/j.bbadis.2017.08.027. Epub 2017 Aug 24. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 28844952 Free PMC article. Review.
Cholangiocarcinoma (CCA) represents a diverse group of epithelial cancers associated with the biliary tract, and can best be stratified anatomically into intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA) subsets. ...For example, targeting cancer associated fibroblast …
Cholangiocarcinoma (CCA) represents a diverse group of epithelial cancers associated with the biliary tract, and can best be stratifi …
Pathology of Cholangiocarcinomas.
Guedj N. Guedj N. Curr Oncol. 2022 Dec 26;30(1):370-380. doi: 10.3390/curroncol30010030. Curr Oncol. 2022. PMID: 36661679 Free PMC article. Review.
Cholangiocarcinomas (CCA) are heterogeneous tumors that arise from epithelial cells of the biliary tract. They represent the second primary liver malignancy, after hepatocellular carcinoma. ...According to their location on the biliary tract, intrahepatic, pe …
Cholangiocarcinomas (CCA) are heterogeneous tumors that arise from epithelial cells of the biliary tract. They represent the s …
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes.
Song Z, Lin S, Wu X, Ren X, Wu Y, Wen H, Qian B, Lin H, Huang Y, Zhao C, Wang N, Huang Y, Peng B, Li X, Peng H, Shen S. Song Z, et al. Hepatol Int. 2023 Oct;17(5):1300-1317. doi: 10.1007/s12072-023-10556-3. Epub 2023 Jun 27. Hepatol Int. 2023. PMID: 37368186 Free PMC article.
IF and IHC showed that HBsAg staining was only visible in HBV (+) ICC fresh tissues and organoids, HBsAg expression was negative in bile duct cells in the portal area. Quantitative PCR assay has shown that the expression of HBs antigen and HBx in normal hepat …
IF and IHC showed that HBsAg staining was only visible in HBV (+) ICC fresh tissues and organoids, HBsAg expression was negative in bile
Extracellular Vesicles in Hepatobiliary Malignancies.
Lapitz A, Arbelaiz A, Olaizola P, Aranburu A, Bujanda L, Perugorria MJ, Banales JM. Lapitz A, et al. Front Immunol. 2018 Oct 12;9:2270. doi: 10.3389/fimmu.2018.02270. eCollection 2018. Front Immunol. 2018. PMID: 30369925 Free PMC article. Review.
Primary hepatobiliary malignancies include a heterogeneous group of cancers with dismal prognosis, among which hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and hepatoblastoma (HB) stand out. These tumors mainly arise from the malignant transformation of hepato …
Primary hepatobiliary malignancies include a heterogeneous group of cancers with dismal prognosis, among which hepatocellular carcinoma
Chemoresistance and chemosensitization in cholangiocarcinoma.
Marin JJG, Lozano E, Herraez E, Asensio M, Di Giacomo S, Romero MR, Briz O, Serrano MA, Efferth T, Macias RIR. Marin JJG, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1444-1453. doi: 10.1016/j.bbadis.2017.06.005. Epub 2017 Jul 7. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 28600147 Free article. Review.
Some of these characteristics are shared with other types of liver cancer, namely hepatocellular carcinoma and hepatoblastoma. An important goal in modern oncologic pharmacology is to develop novel strategies to overcome CCA chemoresistance either by increasing drug specif …
Some of these characteristics are shared with other types of liver cancer, namely hepatocellular carcinoma and hepatoblastoma. An imp …
Biliary carcinogenesis in pancreaticobiliary maljunction.
Kamisawa T, Kuruma S, Chiba K, Tabata T, Koizumi S, Kikuyama M. Kamisawa T, et al. J Gastroenterol. 2017 Feb;52(2):158-163. doi: 10.1007/s00535-016-1268-z. Epub 2016 Oct 4. J Gastroenterol. 2017. PMID: 27704265 Review.
According to the results of a nationwide survey, bile duct and gallbladder cancers were found in 6.9 and 13.4 % of adult patients with congenital biliary dilatation, respectively, and in 3.1 and 37.4 % of those with PBM without biliary dilatation, respectively. Bili …
According to the results of a nationwide survey, bile duct and gallbladder cancers were found in 6.9 and 13.4 % of adult patie …
Liver Fluke-Associated Biliary Tract Cancer.
Prueksapanich P, Piyachaturawat P, Aumpansub P, Ridtitid W, Chaiteerakij R, Rerknimitr R. Prueksapanich P, et al. Gut Liver. 2018 May 15;12(3):236-245. doi: 10.5009/gnl17102. Gut Liver. 2018. PMID: 28783896 Free PMC article. Review.
Cholangiocarcinoma (CCA) is an aggressive cancer arising from epithelial cells of the bile duct. Most patients with CCA have an unresectable tumor at the time of diagnosis. ...The "liver fluke-cholangiocarcinoma" carcinogenesis pathways consist of mech …
Cholangiocarcinoma (CCA) is an aggressive cancer arising from epithelial cells of the bile duct. Most patients w …
236 results