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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1948 4
1951 9
1952 13
1953 17
1954 17
1955 3
1956 4
1957 4
1958 3
1959 5
1962 1
1963 3
1964 1
1965 10
1966 14
1967 30
1968 32
1969 45
1970 26
1971 57
1972 47
1973 63
1974 54
1975 41
1976 65
1977 34
1978 29
1979 35
1980 24
1981 34
1982 31
1983 41
1984 36
1985 39
1986 27
1987 29
1988 41
1989 35
1990 42
1991 40
1992 36
1993 39
1994 53
1995 39
1996 47
1997 48
1998 46
1999 56
2000 49
2001 51
2002 61
2003 59
2004 54
2005 74
2006 65
2007 59
2008 82
2009 81
2010 86
2011 94
2012 117
2013 127
2014 131
2015 142
2016 128
2017 163
2018 183
2019 172
2020 164
2021 132
2022 111
2023 104
2024 40

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3,713 results

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Page 1
Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections.
Luetkemeyer AF, Donnell D, Dombrowski JC, Cohen S, Grabow C, Brown CE, Malinski C, Perkins R, Nasser M, Lopez C, Vittinghoff E, Buchbinder SP, Scott H, Charlebois ED, Havlir DV, Soge OO, Celum C; DoxyPEP Study Team. Luetkemeyer AF, et al. N Engl J Med. 2023 Apr 6;388(14):1296-1306. doi: 10.1056/NEJMoa2211934. N Engl J Med. 2023. PMID: 37018493 Free PMC article. Clinical Trial.
BACKGROUND: Interventions to reduce sexually transmitted infections (STIs) among men who have sex with men (MSM) are needed. METHODS: We conducted an open-label, randomized study involving MSM and transgender women who were taking preexposure prophylaxis (PrEP) against hum …
BACKGROUND: Interventions to reduce sexually transmitted infections (STIs) among men who have sex with men (MSM) are needed. METHODS: We con …
Treatment of syphilis: a systematic review.
Clement ME, Okeke NL, Hicks CB. Clement ME, et al. JAMA. 2014 Nov 12;312(18):1905-17. doi: 10.1001/jama.2014.13259. JAMA. 2014. PMID: 25387188 Free PMC article. Review.
Serologic response to treatment should be evident by 6 months in early syphilis but is generally slower (12-24 months) for latent syphilis. Evidence defining treatment for HIV-infected persons and for pregnant women is limited, but available data support penicillin …
Serologic response to treatment should be evident by 6 months in early syphilis but is generally slower (12-24 months) for latent …
Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial.
Molina JM, Charreau I, Chidiac C, Pialoux G, Cua E, Delaugerre C, Capitant C, Rojas-Castro D, Fonsart J, Bercot B, Bébéar C, Cotte L, Robineau O, Raffi F, Charbonneau P, Aslan A, Chas J, Niedbalski L, Spire B, Sagaon-Teyssier L, Carette D, Mestre SL, Doré V, Meyer L; ANRS IPERGAY Study Group. Molina JM, et al. Lancet Infect Dis. 2018 Mar;18(3):308-317. doi: 10.1016/S1473-3099(17)30725-9. Epub 2017 Dec 8. Lancet Infect Dis. 2018. PMID: 29229440 Clinical Trial.
METHODS: All participants attending their scheduled visit in the open-label extension of the ANRS IPERGAY trial in France (men aged 18 years or older having condomless sex with men and using pre-exposure prophylaxis for HIV with tenofovir disoproxil fumarate plus emtricita …
METHODS: All participants attending their scheduled visit in the open-label extension of the ANRS IPERGAY trial in France (men aged 1 …
Syphilis.
Sadoghi B, Stary G, Wolf P. Sadoghi B, et al. J Dtsch Dermatol Ges. 2023 May;21(5):504-517. doi: 10.1111/ddg.14999. J Dtsch Dermatol Ges. 2023. PMID: 37183747
Syphilis is a curable systemic infectious disease with a clear increase in incidence in recent years. ...Penicillin G remains the treatment of choice in all stages of syphilis....
Syphilis is a curable systemic infectious disease with a clear increase in incidence in recent years. ...Penicillin G remains the tre …
Clinical Efficacy of Cefixime for the Treatment of Early Syphilis.
Stafylis C, Keith K, Mehta S, Tellalian D, Burian P, Millner C, Klausner JD. Stafylis C, et al. Clin Infect Dis. 2021 Sep 7;73(5):907-910. doi: 10.1093/cid/ciab187. Clin Infect Dis. 2021. PMID: 33640982 Free PMC article. Clinical Trial.
Safe and efficacious alternative treatment options for syphilis are necessary. This randomized, 2-arm, noncomparative pilot study evaluated the efficacy of oral cefixime 400 mg in achieving a 4-fold rapid plasma reagin titer decrease by 3 or 6 months after treatment …
Safe and efficacious alternative treatment options for syphilis are necessary. This randomized, 2-arm, noncomparative pilot st …
School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents.
Mason-Jones AJ, Sinclair D, Mathews C, Kagee A, Hillman A, Lombard C. Mason-Jones AJ, et al. Cochrane Database Syst Rev. 2016 Nov 8;11(11):CD006417. doi: 10.1002/14651858.CD006417.pub3. Cochrane Database Syst Rev. 2016. PMID: 27824221 Free PMC article. Review.
We handsearched the reference lists of all relevant papers. SELECTION CRITERIA: We included randomized controlled trials (RCTs), both individually randomized and cluster-randomized, that evaluated school-based programmes aimed at improving the sexual and repr …
We handsearched the reference lists of all relevant papers. SELECTION CRITERIA: We included randomized controlled trials (RCTs), both …
Doxycycline prophylaxis to reduce incident syphilis among HIV-infected men who have sex with men who continue to engage in high-risk sex: a randomized, controlled pilot study.
Bolan RK, Beymer MR, Weiss RE, Flynn RP, Leibowitz AA, Klausner JD. Bolan RK, et al. Sex Transm Dis. 2015 Feb;42(2):98-103. doi: 10.1097/OLQ.0000000000000216. Sex Transm Dis. 2015. PMID: 25585069 Free PMC article. Clinical Trial.
Because of synergy between syphilis and HIV infections, innovative means for controlling incident syphilis infections are needed. ...Safe and effective biomedical tools should be included in the efforts to control transmission of syphilis, especially in this …
Because of synergy between syphilis and HIV infections, innovative means for controlling incident syphilis infections are need …
Combination of Amoxicillin 3000 mg and Probenecid Versus 1500 mg Amoxicillin Monotherapy for Treating Syphilis in Patients With Human Immunodeficiency Virus: An Open-Label, Randomized, Controlled, Non-Inferiority Trial.
Ando N, Mizushima D, Omata K, Nemoto T, Inamura N, Hiramoto S, Takano M, Aoki T, Watanabe K, Uemura H, Shiojiri D, Yanagawa Y, Tanuma J, Teruya K, Kikuchi Y, Gatanaga H, Oka S. Ando N, et al. Clin Infect Dis. 2023 Sep 11;77(5):779-787. doi: 10.1093/cid/ciad278. Clin Infect Dis. 2023. PMID: 37157863 Clinical Trial.
METHODS: We conducted an open-label, randomized, controlled, non-inferiority trial between 31 August 2018, and 3 February 2022, to compare 1500 mg low-dose amoxicillin monotherapy with the combination of 3000 mg amoxicillin and probenecid (non-inferiority margin 10% …
METHODS: We conducted an open-label, randomized, controlled, non-inferiority trial between 31 August 2018, and 3 February 2022 …
Investigating latent syphilis in HIV treatment-experienced Ethiopians and response to therapy.
Girma S, Amogne W. Girma S, et al. PLoS One. 2022 Jul 12;17(7):e0270878. doi: 10.1371/journal.pone.0270878. eCollection 2022. PLoS One. 2022. PMID: 35819944 Free PMC article. Clinical Trial.
METHODS: A prospective follow-up study was conducted on PWH and latent syphilis. The cases were randomly assigned to receive either benzathine penicillin G (BPG) or doxycycline (DOXY), and the posttreatment response was evaluated after 12 and 24 months. ...Syphil …
METHODS: A prospective follow-up study was conducted on PWH and latent syphilis. The cases were randomly assigned to receive e …
Treatment of syphilis, 1989.
Zenker PN, Rolfs RT. Zenker PN, et al. Rev Infect Dis. 1990 Jul-Aug;12 Suppl 6:S590-609. doi: 10.1093/clinids/12.supplement_6.s590. Rev Infect Dis. 1990. PMID: 2201075 Review.
With the introduction of penicillin after World War II, the incidence of syphilis in the United States decreased. Because of penicillin's great success, clinical trials stopped after an initial period of intensive investigation. ...Although the recommended penicilli …
With the introduction of penicillin after World War II, the incidence of syphilis in the United States decreased. Because of penicill …
3,713 results