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Quoted phrase not found in phrase index: "Thrombophilia due to thrombin defect"
Page 1
Antithrombin.
Hepner M, Karlaftis V. Hepner M, et al. Methods Mol Biol. 2013;992:355-64. doi: 10.1007/978-1-62703-339-8_28. Methods Mol Biol. 2013. PMID: 23546728
Given that AT is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result in excessive thrombin generation. As a vast array of mutations are responsible for hereditary AT deficiencies, screening for their pr …
Given that AT is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result …
Disseminated intravascular coagulation: testing and diagnosis.
Wada H, Matsumoto T, Yamashita Y, Hatada T. Wada H, et al. Clin Chim Acta. 2014 Sep 25;436:130-4. doi: 10.1016/j.cca.2014.04.020. Epub 2014 Apr 30. Clin Chim Acta. 2014. PMID: 24792730 Review.
Abnormalities of the hemostatic system in patients with DIC result from the sum of vectors for hypercoagulation and hyperfibrinolysis. ...Both the antithrombin (AT) and protein C (PC) levels are significantly low in patients with septic DIC, and reduced amounts of AT and P …
Abnormalities of the hemostatic system in patients with DIC result from the sum of vectors for hypercoagulation and hyperfibrinolysis …
Protein S.
Hepner M, Karlaftis V. Hepner M, et al. Methods Mol Biol. 2013;992:373-81. doi: 10.1007/978-1-62703-339-8_30. Methods Mol Biol. 2013. PMID: 23546730
Given that PS is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result in excessive thrombin generation. As a vast array of mutations are responsible for hereditary PS deficiencies, screening for their pr …
Given that PS is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result …
Inherited antithrombin deficiency: a review.
Patnaik MM, Moll S. Patnaik MM, et al. Haemophilia. 2008 Nov;14(6):1229-39. doi: 10.1111/j.1365-2516.2008.01830.x. Haemophilia. 2008. PMID: 19141163 Review.
Antithrombin (AT) is a potent inactivator of thrombin and factor Xa and the major inhibitor of blood coagulation. ...Type II is subdivided into the more common, but less thrombogenic, type IIb deficiency caused by a defect in the heparin-binding region of AT and the …
Antithrombin (AT) is a potent inactivator of thrombin and factor Xa and the major inhibitor of blood coagulation. ...Type II is subdi …
The phenotypic and genetic assessment of antithrombin deficiency.
Cooper PC, Coath F, Daly ME, Makris M. Cooper PC, et al. Int J Lab Hematol. 2011 Jun;33(3):227-37. doi: 10.1111/j.1751-553X.2011.01307.x. Epub 2011 Mar 15. Int J Lab Hematol. 2011. PMID: 21401902 Review.
RESULTS: Many patients with AT deficiency have a type II defect and these defects may not be detected by all routine diagnostic assays. ...Factor Xa based assays may be particularly sensitive to certain heparin binding defects, and sensitivity of assays to bo …
RESULTS: Many patients with AT deficiency have a type II defect and these defects may not be detected by all routine diagnosti …
Thrombotic disease in the myeloproliferative neoplasms.
Falanga A, Marchetti M. Falanga A, et al. Hematology Am Soc Hematol Educ Program. 2012;2012:571-81. doi: 10.1182/asheducation-2012.1.571. Hematology Am Soc Hematol Educ Program. 2012. PMID: 23233637 Review.
Mechanisms involved in the pathogenesis of the acquired thrombophilic state associated with these diseases include abnormalities of MPN clone-derived blood cells, which display prothrombotic features, and abnormalities of normal vascular cells, which become procoagu …
Mechanisms involved in the pathogenesis of the acquired thrombophilic state associated with these diseases include abnormalities of M …
Laboratory diagnosis of dysfibrinogenemia.
Cunningham MT, Brandt JT, Laposata M, Olson JD. Cunningham MT, et al. Arch Pathol Lab Med. 2002 Apr;126(4):499-505. doi: 10.5858/2002-126-0499-LDOD. Arch Pathol Lab Med. 2002. PMID: 11900586 Free article. Review.
Dysfibrinogenemia is a coagulation disorder caused by a variety of structural abnormalities in the fibrinogen molecule that result in abnormal fibrinogen function. ...The inherited form is diagnosed by demonstrating similar laboratory test abnormalities in family me …
Dysfibrinogenemia is a coagulation disorder caused by a variety of structural abnormalities in the fibrinogen molecule that result in …
Protein C.
Hepner M, Karlaftis V. Hepner M, et al. Methods Mol Biol. 2013;992:365-72. doi: 10.1007/978-1-62703-339-8_29. Methods Mol Biol. 2013. PMID: 23546729
Given that PC is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result in excessive thrombin generation. As a vast array of mutations are responsible for hereditary PC deficiencies, screening for their pr …
Given that PC is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result …
Revisiting antithrombin in health and disease, congenital deficiencies and genetic variants, and laboratory studies on α and β forms.
Amiral J, Seghatchian J. Amiral J, et al. Transfus Apher Sci. 2018 Apr;57(2):291-297. doi: 10.1016/j.transci.2018.04.010. Epub 2018 Apr 19. Transfus Apher Sci. 2018. PMID: 29784539 Review.
Antithrombin [AT] is the main inhibitor for activated plasma coagulation serine esterases, inhibiting thrombin, Factors Xa and IXa, but also Factors XIIa, XIa, VIIa, kallicrein, and plasmin. ...However, AT is the major inhibitor of thrombin in the blood circulation. …
Antithrombin [AT] is the main inhibitor for activated plasma coagulation serine esterases, inhibiting thrombin, Factors Xa and IXa, b …
Therapeutic strategies in patients with coagulopathy and disseminated intravascular coagulation: awareness of the phase-dependent characteristics.
Iba T, Warkentin TE, Connors JM, Levy JH. Iba T, et al. Minerva Med. 2021 Dec;112(6):701-712. doi: 10.23736/S0026-4806.21.07469-3. Epub 2021 Mar 12. Minerva Med. 2021. PMID: 33709675 Review.
INTRODUCTION: Disseminated intravascular coagulation (DIC) has long been understood as a condition where both thrombotic and hemostatic abnormalities coexist. DIC is a difficult complication for clinicians to manage as it is due to multiple underlying complications of path …
INTRODUCTION: Disseminated intravascular coagulation (DIC) has long been understood as a condition where both thrombotic and hemostatic a …
95 results