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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1983 3
1985 2
1986 1
1987 4
1988 2
1989 1
1990 2
1991 1
1992 6
1993 8
1994 5
1995 9
1996 7
1997 3
1998 5
1999 6
2000 10
2001 11
2002 7
2003 6
2004 12
2005 8
2006 12
2007 7
2008 10
2009 8
2010 8
2011 11
2012 9
2013 18
2014 13
2015 17
2016 17
2017 13
2018 14
2019 10
2020 11
2021 7
2022 7
2023 7
2024 4

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296 results

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Page 1
CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis.
Yang H, Zhang Q, Xu M, Wang L, Chen X, Feng Y, Li Y, Zhang X, Cui W, Jia X. Yang H, et al. Mol Cancer. 2020 Feb 27;19(1):41. doi: 10.1186/s12943-020-01165-x. Mol Cancer. 2020. PMID: 32103760 Free PMC article.
RESULTS: Increasing expression of CCL2 correlated with TAMs accumulation in esophageal carcinogenesis, and they both predicts poor prognosis in ESCC cohort. Animal studies show blockade of CCL2-CCR2 axis strongly reduces tumor incidence by hindering TAMs recruitment and th …
RESULTS: Increasing expression of CCL2 correlated with TAMs accumulation in esophageal carcinogenesis, and they both predicts poor pr …
Thresholds for carcinogens.
Calabrese EJ, Priest ND, Kozumbo WJ. Calabrese EJ, et al. Chem Biol Interact. 2021 May 25;341:109464. doi: 10.1016/j.cbi.2021.109464. Epub 2021 Apr 3. Chem Biol Interact. 2021. PMID: 33823170 Review.
Evidence for and against the concept of carcinogen-induced tumor latency is presented, discussed, and then examined with respect to its relationship to dose, dose rates, and the dose-related concepts of initiation, tumor promotion, tumor regression, tumor incidence, …
Evidence for and against the concept of carcinogen-induced tumor latency is presented, discussed, and then examined with respect to its rela …
Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling.
Lin SC, Liao YC, Chen PM, Yang YY, Wang YH, Tung SL, Chuang CM, Sung YW, Jang TH, Chuang SE, Wang LH. Lin SC, et al. J Biomed Sci. 2022 Dec 22;29(1):109. doi: 10.1186/s12929-022-00888-x. J Biomed Sci. 2022. PMID: 36550569 Free PMC article.
Anchorage independent assay, Western blot, RNA interference, confocal analysis and neutralizing antibody treatment were performed to analyze the effects of POSTN on tumor promotion and to explore the underlying mechanism. Chemotaxis, flow cytometry and cytokine arra …
Anchorage independent assay, Western blot, RNA interference, confocal analysis and neutralizing antibody treatment were performed to analyze …
Final report of the safety assessment of niacinamide and niacin.
Cosmetic Ingredient Review Expert Panel. Cosmetic Ingredient Review Expert Panel. Int J Toxicol. 2005;24 Suppl 5:1-31. doi: 10.1080/10915810500434183. Int J Toxicol. 2005. PMID: 16596767 Review.
Short-term oral, parenteral, or dermal toxicity studies did not identify significant irreversible effects. Niacinamide, evaluated in an in vitro test to predict ocular irritation, was not an acute ocular hazard. Animal testing of Niacinamide in rabbits in actual formulatio …
Short-term oral, parenteral, or dermal toxicity studies did not identify significant irreversible effects. Niacinamide, evaluated in an in v …
Nitric oxide and hormesis.
Calabrese EJ, Agathokleous E, Dhawan G, Kapoor R, Dhawan V, Manes PK, Calabrese V. Calabrese EJ, et al. Nitric Oxide. 2023 Apr 1;133:1-17. doi: 10.1016/j.niox.2023.02.001. Epub 2023 Feb 8. Nitric Oxide. 2023. PMID: 36764605 Review.
A substantial reporting of such NO-induced hormetic effects was identified with particular focus on wound healing, tumor promotion, and sperm biology, including mechanistic assessment and potential for translational applications. ...The extensive documentation of NO …
A substantial reporting of such NO-induced hormetic effects was identified with particular focus on wound healing, tumor promotion …
Systemic Immune-Inflammation Index Predicts Tumor Recurrence after Radical Resection for Colorectal Cancer.
Nakamoto S, Ohtani Y, Sakamoto I, Hosoda A, Ihara A, Naitoh T. Nakamoto S, et al. Tohoku J Exp Med. 2023 Nov 25;261(3):229-238. doi: 10.1620/tjem.2023.J074. Epub 2023 Sep 7. Tohoku J Exp Med. 2023. PMID: 37673651 Free article.
The systemic inflammatory response is associated with tumor promotion and suppression. Accumulating evidence shows that peripheral blood markers of inflammatory response predict clinical outcomes in various human cancers. ...Our study suggests that SII and ly …
The systemic inflammatory response is associated with tumor promotion and suppression. Accumulating evidence shows that periph …
Formaldehyde: Another hormesis-inducing chemical.
Agathokleous E, Calabrese EJ. Agathokleous E, et al. Environ Res. 2021 Aug;199:111395. doi: 10.1016/j.envres.2021.111395. Epub 2021 May 25. Environ Res. 2021. PMID: 34048749 Review.
Hormetic in vitro responses were reported in several cancerous/tumorous cell lines, suggesting that FA has the potential to influence tumor promotion within a specific concentration range and biological context. These observations suggest that FA commonly act …
Hormetic in vitro responses were reported in several cancerous/tumorous cell lines, suggesting that FA has the potential to influence tum …
Role of long pentraxin PTX3 in cancer.
Li D, Hao Z, Nan Y, Chen Y. Li D, et al. Clin Exp Med. 2023 Dec;23(8):4401-4411. doi: 10.1007/s10238-023-01137-7. Epub 2023 Jul 12. Clin Exp Med. 2023. PMID: 37438568 Review.
Therefore, it is particularly urgent to study specific mechanisms of cancer and develop effective prediction and treatment methods. Long Pentraxin PTX3 is a soluble pattern recognition molecule produced by various cells in inflammatory sites, which plays a role as a promot …
Therefore, it is particularly urgent to study specific mechanisms of cancer and develop effective prediction and treatment methods. L …
Protein kinase C (PKC) isoforms in cancer, tumor promotion and tumor suppression.
Isakov N. Isakov N. Semin Cancer Biol. 2018 Feb;48:36-52. doi: 10.1016/j.semcancer.2017.04.012. Epub 2017 May 29. Semin Cancer Biol. 2018. PMID: 28571764 Review.
Members of one subgroup of AGC kinases, the protein kinase C (PKC), have been singled out as critical players in carcinogenesis, following their identification as the intracellular receptors of phorbol esters, which exhibit tumor-promoting activities. This observation attr …
Members of one subgroup of AGC kinases, the protein kinase C (PKC), have been singled out as critical players in carcinogenesis, following t …
Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma.
Ding M, Ran X, Qian S, Zhang Y, Wang Z, Dong M, Yang Z, Wu S, Feng X, Zhang J, Zhu L, Niu S, Zhang X. Ding M, et al. Aging (Albany NY). 2023 Dec 29;15(24):15360-15381. doi: 10.18632/aging.205354. Epub 2023 Dec 29. Aging (Albany NY). 2023. PMID: 38180104 Free PMC article.
Oxidative stress (OXS) can directly target intracellular macromolecules and exhibit dual effects of tumor promotion and suppression. METHODS: OXS-related genes (OXRGs) were extracted from public databases, including TARGET and GEO. ...By contrast, OS patients with h …
Oxidative stress (OXS) can directly target intracellular macromolecules and exhibit dual effects of tumor promotion and suppre …
296 results