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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 1
2009 1
2010 1
2011 5
2012 8
2013 7
2014 12
2015 14
2016 14
2017 14
2018 13
2019 21
2020 24
2021 36
2022 38
2023 36
2024 16

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224 results

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Page 1
Targeting p53 pathways: mechanisms, structures, and advances in therapy.
Wang H, Guo M, Wei H, Chen Y. Wang H, et al. Signal Transduct Target Ther. 2023 Mar 1;8(1):92. doi: 10.1038/s41392-023-01347-1. Signal Transduct Target Ther. 2023. PMID: 36859359 Free PMC article. Review.
Here, we provide a systematic review of the diverse molecular mechanisms of the p53 signaling pathway and how TP53 mutations impact tumor progression. We also discuss key structural features of the p53 protein and its inactivation by oncogenic mutations. ...
Here, we provide a systematic review of the diverse molecular mechanisms of the p53 signaling pathway and how TP53 mutations impact tumor …
Alternative splicing and cancer: a systematic review.
Zhang Y, Qian J, Gu C, Yang Y. Zhang Y, et al. Signal Transduct Target Ther. 2021 Feb 24;6(1):78. doi: 10.1038/s41392-021-00486-7. Signal Transduct Target Ther. 2021. PMID: 33623018 Free PMC article.
The aim of the present study was to conduct a systematic review in order to describe the regulatory mechanisms of alternative splicing, as well as its functions in tumor cells, from proliferation and apoptosis to invasion and metastasis, and from angiogenesis to metabolism. The a …
The aim of the present study was to conduct a systematic review in order to describe the regulatory mechanisms of alternative splicing, as w …
Differentiated Thyroid Cancer-Treatment: State of the Art.
Schmidbauer B, Menhart K, Hellwig D, Grosse J. Schmidbauer B, et al. Int J Mol Sci. 2017 Jun 17;18(6):1292. doi: 10.3390/ijms18061292. Int J Mol Sci. 2017. PMID: 28629126 Free PMC article. Review.
Although a benefit for overall survival has not been shown yet, these new drugs can slow down tumor progression. However, they are frequently associated with severe side effects and should be reserved for patients with threatening symptoms only....
Although a benefit for overall survival has not been shown yet, these new drugs can slow down tumor progression. However, they …
Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid: A Systematic Review and Meta-analysis.
van Dijk SPJ, Coerts HI, Gunput STG, van Velsen EFS, Medici M, Moelker A, Peeters RP, Verhoef C, van Ginhoven TM. van Dijk SPJ, et al. JAMA Otolaryngol Head Neck Surg. 2022 Apr 1;148(4):317-325. doi: 10.1001/jamaoto.2021.4381. JAMA Otolaryngol Head Neck Surg. 2022. PMID: 35142816 Free PMC article.
MAIN OUTCOMES AND MEASURES: The primary outcome was the complete disappearance rate of mPTC. Secondary outcomes were tumor progression and complications. RESULTS: Fifteen studies were included in this meta-analysis. ...The pooled complete disappearance rate at the e …
MAIN OUTCOMES AND MEASURES: The primary outcome was the complete disappearance rate of mPTC. Secondary outcomes were tumor progres …
Definition, Incidence, and Challenges for Assessment of Hyperprogressive Disease During Cancer Treatment With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis.
Park HJ, Kim KW, Won SE, Yoon S, Chae YK, Tirumani SH, Ramaiya NH. Park HJ, et al. JAMA Netw Open. 2021 Mar 1;4(3):e211136. doi: 10.1001/jamanetworkopen.2021.1136. JAMA Netw Open. 2021. PMID: 33760090 Free PMC article.
IMPORTANCE: Hyperprogressive disease (HPD) is a recognized pattern of rapid tumor progression during immune checkpoint inhibitor (ICI) treatment. ...
IMPORTANCE: Hyperprogressive disease (HPD) is a recognized pattern of rapid tumor progression during immune checkpoint inhibit …
Sorafenib in melanoma.
Mangana J, Levesque MP, Karpova MB, Dummer R. Mangana J, et al. Expert Opin Investig Drugs. 2012 Apr;21(4):557-68. doi: 10.1517/13543784.2012.665872. Epub 2012 Mar 7. Expert Opin Investig Drugs. 2012. PMID: 22394203 Review.
INTRODUCTION: Sorafenib is an orally available multi-kinase inhibitor that inhibits tumor proliferation by targeting multiple kinases including the vascular endothelial growth factor receptors VEGFR1, VEGFR2, VEGFR3 and the platelet-derived growth factor receptor PDGFR, and it ta …
INTRODUCTION: Sorafenib is an orally available multi-kinase inhibitor that inhibits tumor proliferation by targeting multiple kinases includ …
Tumor Immune Microenvironment and Its Related miRNAs in Tumor Progression.
Xing Y, Ruan G, Ni H, Qin H, Chen S, Gu X, Shang J, Zhou Y, Tao X, Zheng L. Xing Y, et al. Front Immunol. 2021 May 18;12:624725. doi: 10.3389/fimmu.2021.624725. eCollection 2021. Front Immunol. 2021. PMID: 34084160 Free PMC article.
Investigating the role of miRNA in regulating the tumor immune microenvironment will help elucidate the specific mechanisms of interaction between immune cells and tumor cells, and may facilitate the use of miRNA as a predictor of immune disorders in tumor progression …
Investigating the role of miRNA in regulating the tumor immune microenvironment will help elucidate the specific mechanisms of interaction b …
Corticotroph tumor progression after bilateral adrenalectomy (Nelson's syndrome): systematic review and expert consensus recommendations.
Reincke M, Albani A, Assie G, Bancos I, Brue T, Buchfelder M, Chabre O, Ceccato F, Daniele A, Detomas M, Di Dalmazi G, Elenkova A, Findling J, Grossman AB, Gomez-Sanchez CE, Heaney AP, Honegger J, Karavitaki N, Lacroix A, Laws ER, Losa M, Murakami M, Newell-Price J, Pecori Giraldi F, Pérez-Rivas LG, Pivonello R, Rainey WE, Sbiera S, Schopohl J, Stratakis CA, Theodoropoulou M, van Rossum EFC, Valassi E, Zacharieva S, Rubinstein G, Ritzel K. Reincke M, et al. Eur J Endocrinol. 2021 Mar;184(3):P1-P16. doi: 10.1530/EJE-20-1088. Eur J Endocrinol. 2021. PMID: 33444221 Free PMC article.
BACKGROUND: Corticotroph tumor progression (CTP) leading to Nelson's syndrome (NS) is a severe and difficult-to-treat complication subsequent to bilateral adrenalectomy (BADX) for Cushing's disease. ...
BACKGROUND: Corticotroph tumor progression (CTP) leading to Nelson's syndrome (NS) is a severe and difficult-to-treat complica …
Patient-Derived Xenotransplant of CNS Neoplasms in Zebrafish: A Systematic Review.
Sarmiento BE, Callegari S, Ghotme KA, Akle V. Sarmiento BE, et al. Cells. 2022 Apr 2;11(7):1204. doi: 10.3390/cells11071204. Cells. 2022. PMID: 35406768 Free PMC article. Review.
The zebrafish is a suitable biological model for understanding tumor progression and the effects of different treatments. This model offers new perspectives in providing personalized care and improving outcomes for patients living with central nervous system tumors. …
The zebrafish is a suitable biological model for understanding tumor progression and the effects of different treatments. This …
Tissue factor in tumor microenvironment: a systematic review.
Han X, Guo B, Li Y, Zhu B. Han X, et al. J Hematol Oncol. 2014 Aug 1;7:54. doi: 10.1186/s13045-014-0054-8. J Hematol Oncol. 2014. PMID: 25084809 Free PMC article. Review.
In this review, we summarize our current understanding of the TF regulation and roles in tumor progression and clinical complications....
In this review, we summarize our current understanding of the TF regulation and roles in tumor progression and clinical compli …
224 results