Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1962 2
1963 1
1965 2
1967 1
1968 1
1969 5
1970 12
1971 9
1972 13
1973 21
1974 20
1975 45
1976 63
1977 67
1978 81
1979 93
1980 109
1981 89
1982 113
1983 143
1984 184
1985 206
1986 202
1987 197
1988 162
1989 206
1990 237
1991 236
1992 250
1993 222
1994 204
1995 191
1996 208
1997 225
1998 248
1999 250
2000 290
2001 291
2002 317
2003 323
2004 381
2005 450
2006 485
2007 503
2008 522
2009 543
2010 569
2011 626
2012 712
2013 693
2014 715
2015 772
2016 854
2017 838
2018 904
2019 904
2020 1073
2021 1042
2022 901
2023 869
2024 388

Text availability

Article attribute

Article type

Publication date

Search Results

18,232 results

Results by year

Filters applied: . Clear all
Page 1
Recent Advances in the Synthesis of Ibuprofen and Naproxen.
Ha MW, Paek SM. Ha MW, et al. Molecules. 2021 Aug 7;26(16):4792. doi: 10.3390/molecules26164792. Molecules. 2021. PMID: 34443379 Free PMC article. Review.
Herein, we review the recent progress in the synthesis of representative nonsteroidal anti-inflammatory drugs (NSAIDs), ibuprofen and naproxen. Although these drugs were discovered over 50 years ago, novel practical and asymmetric approaches are still being developed for t …
Herein, we review the recent progress in the synthesis of representative nonsteroidal anti-inflammatory drugs (NSAIDs), ibuprofen and …
Ibuprofen.
Kantor TG. Kantor TG. Ann Intern Med. 1979 Dec;91(6):877-82. doi: 10.7326/0003-4819-91-6-877. Ann Intern Med. 1979. PMID: 391117 Review.
Ibuprofen was introduced in England in 1967 and in the United States in 1974 as an anti-inflammatory drug in humans. ...It inhibits prostaglandin synthesis and has no effect on the adrenopituitary axis, making it a nonsteroidal agent. Ibuprofen has been shown to be …
Ibuprofen was introduced in England in 1967 and in the United States in 1974 as an anti-inflammatory drug in humans. ...It inhibits p …
Ibuprofen: Toxicology and Biodegradation of an Emerging Contaminant.
Jan-Roblero J, Cruz-Maya JA. Jan-Roblero J, et al. Molecules. 2023 Feb 23;28(5):2097. doi: 10.3390/molecules28052097. Molecules. 2023. PMID: 36903343 Free PMC article. Review.
Because of its high human consumption rate and low environmental degradation rate, ibuprofen represents an emerging environmental problem. Ibuprofen enters the environment from different sources and accumulates in natural environmental matrices. ...In several countr …
Because of its high human consumption rate and low environmental degradation rate, ibuprofen represents an emerging environmental pro …
Clinical pharmacokinetics of ibuprofen. The first 30 years.
Davies NM. Davies NM. Clin Pharmacokinet. 1998 Feb;34(2):101-54. doi: 10.2165/00003088-199834020-00002. Clin Pharmacokinet. 1998. PMID: 9515184 Review.
Ibuprofen binds extensively, in a concentration-dependent manner, to plasma albumin. ...Hepatic disease and cystic fibrosis can alter the disposition kinetics of ibuprofen. Ibuprofen is not excreted in substantial concentrations into breast milk. ...
Ibuprofen binds extensively, in a concentration-dependent manner, to plasma albumin. ...Hepatic disease and cystic fibrosis can alter …
Ibuprofen: a monograph.
Aycock DG. Aycock DG. Am Pharm. 1991 Jan;NS31(1):46-9. Am Pharm. 1991. PMID: 2000781 Review.
Nonprescription ibuprofen is useful for managing minor aches and pains, reducing fever, and relieving symptoms of dysmenorrhea. ...Ibuprofen is not recommended for self-treatment in children less than 12 years old....
Nonprescription ibuprofen is useful for managing minor aches and pains, reducing fever, and relieving symptoms of dysmenorrhea. ... …
Ibuprofen Arginate for Rapid-Onset Pain Relief in Daily Practice: A Review of Its Use in Different Pain Conditions.
Cajaraville JP. Cajaraville JP. J Pain Res. 2021 Jan 25;14:117-126. doi: 10.2147/JPR.S280571. eCollection 2021. J Pain Res. 2021. PMID: 33531831 Free PMC article. Review.
Ibuprofen is one of the most frequently used analgesics. One of the concerns related with the oral administration of conventional ibuprofen is the relatively slow absorption, which is clinically a relative inconvenience when rapid-onset analgesic effect is required …
Ibuprofen is one of the most frequently used analgesics. One of the concerns related with the oral administration of conventional …
Ibuprofen: a journey from prescription to over-the-counter use.
Moore N. Moore N. J R Soc Med. 2007;100 Suppl 48:2-6. doi: 10.1177/014107680710004801s01. J R Soc Med. 2007. PMID: 18335846 Review.
Low-dose, OTC ibuprofen has been used for pain relief for over 30 years without any obvious major health issues. ...OTC ibuprofen is at least as effective as aspirin and more effective than paracetamol. ...
Low-dose, OTC ibuprofen has been used for pain relief for over 30 years without any obvious major health issues. ...OTC ibuprofen …
Ibuprofen in acute-care therapy.
Rockwell WB, Ehrlich HP. Rockwell WB, et al. Ann Surg. 1990 Jan;211(1):78-83. doi: 10.1097/00000658-199001000-00014. Ann Surg. 1990. PMID: 2403773 Free PMC article. Review.
Conditions ranging from immunologic response to trauma and sepsis to postburn lung dysfunction to wound edema are improved by the use of ibuprofen. The fact that ibuprofen is effective in the various conditions detailed above, while other steroidal and nonsteroidal …
Conditions ranging from immunologic response to trauma and sepsis to postburn lung dysfunction to wound edema are improved by the use of …
Ibuprofen use and clinical outcomes in COVID-19 patients.
Rinott E, Kozer E, Shapira Y, Bar-Haim A, Youngster I. Rinott E, et al. Clin Microbiol Infect. 2020 Sep;26(9):1259.e5-1259.e7. doi: 10.1016/j.cmi.2020.06.003. Epub 2020 Jun 12. Clin Microbiol Infect. 2020. PMID: 32535147 Free PMC article.
One hundred and seventy-nine (44%) patients had fever, with 32% using paracetamol and 22% using ibuprofen, for symptom-relief. In the ibuprofen group, 3 (3.4%) patients died, whereas in the non-ibuprofen group, 9 (2.8%) patients died (p 0.95). Nine (10.3%) pa …
One hundred and seventy-nine (44%) patients had fever, with 32% using paracetamol and 22% using ibuprofen, for symptom-relief. In the …
18,232 results
You have reached the last available page of results. Please see the User Guide for more information.