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Understanding prediabetes: definition, prevalence, burden and treatment options for an emerging disease.
Rett K, Gottwald-Hostalek U. Rett K, et al. Curr Med Res Opin. 2019 Sep;35(9):1529-1534. doi: 10.1080/03007995.2019.1601455. Epub 2019 Apr 15. Curr Med Res Opin. 2019. PMID: 30935247 Review.
Prediabetes is defined as a state of abnormal glucose homeostasis where blood glucose levels are elevated above those considered normal, but not as high as those required for a diagnosis of diabetes. As a condition intermediate between normal glucos …
Prediabetes is defined as a state of abnormal glucose homeostasis where blood glucose levels are elevated above …
Construction, evaluation, and AOP framework-based application of the EpPRS as a genetic surrogate for assessing environmental pollutants.
Chen S, Xin J, Ding Z, Zhao L, Ben S, Zheng R, Li S, Li H, Shao W, Cheng Y, Zhang Z, Du M, Wang M. Chen S, et al. Environ Int. 2023 Oct;180:108202. doi: 10.1016/j.envint.2023.108202. Epub 2023 Sep 12. Environ Int. 2023. PMID: 37734146 Free article.
Finally, the AKT1-mediated AOP framework illustrated that PCB126 and BDE153 may increase the risk of T2DM by decreasing AKT1 phosphorylation through the cGMP-PKG pathway and promoting abnormal glucose homeostasis. MR analysis showed that digestive system tumo …
Finally, the AKT1-mediated AOP framework illustrated that PCB126 and BDE153 may increase the risk of T2DM by decreasing AKT1 phosphorylation …
Endocrine Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.
Srinivasan V, Lee JH, Menon K, Zimmerman JJ, Bembea MM, Agus MSD; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative. Srinivasan V, et al. Pediatrics. 2022 Jan 1;149(1 Suppl 1):S84-S90. doi: 10.1542/peds.2021-052888M. Pediatrics. 2022. PMID: 34970672 Free article.
STUDY SELECTION: We included studies in which researchers evaluated critically ill children with abnormalities in glucose homeostasis, thyroid function and adrenal function, performance characteristics of assessment and/or scoring tools to screen for endocrine dysfu …
STUDY SELECTION: We included studies in which researchers evaluated critically ill children with abnormalities in glucose homeosta …
What Role Might There Be for Continuous Glucose Monitoring in the Assessment of Diabetes Risk?
Miller E, Polonsky WH, Miller K. Miller E, et al. Diabetes Technol Ther. 2023 Jun;25(S3):S14-S20. doi: 10.1089/dia.2023.0136. Diabetes Technol Ther. 2023. PMID: 37306445
The term "prediabetes" has traditionally been used to describe the state of abnormal glucose homeostasis (dysglycemia) that could eventually lead to developing clinical type 2 diabetes. The HbA1c, oral glucose tolerance testing, and fasting glucose …
The term "prediabetes" has traditionally been used to describe the state of abnormal glucose homeostasis (dysglycemia) …
Glucose homeostasis and genotype-phenotype interplay in cystic fibrosis patients with CFTR gene deltaF508 mutation.
Preumont V, Hermans MP, Lebecque P, Buysschaert M. Preumont V, et al. Diabetes Care. 2007 May;30(5):1187-92. doi: 10.2337/dc06-1915. Epub 2007 Mar 2. Diabetes Care. 2007. PMID: 17337503
OBJECTIVE: We sought to determine the clinical phenotype of adolescent/adult patients with cystic fibrosis, according to heterozygosity or homozygosity for cystic fibrosis transmembrane regulator (CFTR) deltaF508 mutation, and to analyze their characteristics according to gluc …
OBJECTIVE: We sought to determine the clinical phenotype of adolescent/adult patients with cystic fibrosis, according to heterozygosity or h …
Variability in diagnostic evaluation and criteria for gestational diabetes.
Solomon CG, Willett WC, Rich-Edwards J, Hunter DJ, Stampfer MJ, Colditz GA, Manson JE. Solomon CG, et al. Diabetes Care. 1996 Jan;19(1):12-6. doi: 10.2337/diacare.19.1.12. Diabetes Care. 1996. PMID: 8720526
Of women with a physician diagnosis of GDM whose OGTT results were available, 25% failed to meet NDDG criteria for this diagnosis, although all had evidence of abnormal glucose homeostasis. CONCLUSIONS: Screening for GDM is not universal, even among a group o …
Of women with a physician diagnosis of GDM whose OGTT results were available, 25% failed to meet NDDG criteria for this diagnosis, although …
Implications of new diagnostic criteria for abnormal glucose homeostasis in women with previous gestational diabetes.
Kousta E, Lawrence NJ, Penny A, Millauer BA, Robinson S, Dornhorst A, de Swiet M, Steer PJ, Grenfell A, Mather HM, Johnston DG, McCarthy MI. Kousta E, et al. Diabetes Care. 1999 Jun;22(6):933-7. doi: 10.2337/diacare.22.6.933. Diabetes Care. 1999. PMID: 10372245
Overall, 56 women (34%) showed a classification discrepancy between WHO-1985 and ADA-1997 criteria, including 44 with normal fasting glucose by ADA-1997 criteria, but abnormal 2-h glucose by WHO-1985 criteria (40 IGT, 4 diabetes). ...Screening women with prev …
Overall, 56 women (34%) showed a classification discrepancy between WHO-1985 and ADA-1997 criteria, including 44 with normal fasting gluc …
Diabetes: 'tight control' in a comprehensive treatment plan.
Brown DF, Jackson TW. Brown DF, et al. Geriatrics. 1994 Jun;49(6):24-9, 33-6. Geriatrics. 1994. PMID: 8005457 Review.
Two out of every five older Americans have abnormal glucose homeostasis. Approximately 1 in 5 has diabetes mellitus, but one-half of these persons are undiagnosed. ...The key to successful management is to follow through with a treatment plan that deals with …
Two out of every five older Americans have abnormal glucose homeostasis. Approximately 1 in 5 has diabetes mellitus, bu …