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Validity of EQ-5D-5L health-related quality of life questionnaire in self-reported diabetes: evidence from a general population survey.
Jankowska A, Młyńczak K, Golicki D. Jankowska A, et al. Health Qual Life Outcomes. 2021 May 5;19(1):138. doi: 10.1186/s12955-021-01780-2. Health Qual Life Outcomes. 2021. PMID: 33952271 Free PMC article.
The convergence between related EQ-5D-5L and EQ-5D-3L or SF-6D dimensions was stronger than between unrelated dimensions. The Bland-Altman analysis showed a mean difference between EQ-5D-5L and EQ-5D-3L, SF-6D, EQ VAS/100 index scores of 0.047, 0.165 a …
The convergence between related EQ-5D-5L and EQ-5D-3L or SF-6D dimensions was stronger than between unrelated dimensions. The …
Longitudinal study of patients' health-related quality of life using EQ-5D-3L in 11 Swedish National Quality Registers.
Teni FS, Rolfson O, Devlin N, Parkin D, Nauclér E, Burström K; Swedish Quality Register (SWEQR) Study Group. Teni FS, et al. BMJ Open. 2022 Jan 6;12(1):e048176. doi: 10.1136/bmjopen-2020-048176. BMJ Open. 2022. PMID: 34992101 Free PMC article.
OBJECTIVE: To compare problems reported in the five EQ-5D-3L dimensions and EQ VAS scores at baseline and at 1-year follow-up among different patient groups and specific diagnoses in 11 National Quality Registers (NQRs) and to compare these with the general population. ... …
OBJECTIVE: To compare problems reported in the five EQ-5D-3L dimensions and EQ VAS scores at baseline and at 1-year follow-up among d …
Individualization of levodopa treatment using a microtablet dispenser and ambulatory accelerometry.
Johansson D, Ericsson A, Johansson A, Medvedev A, Nyholm D, Ohlsson F, Senek M, Spira J, Thomas I, Westin J, Bergquist F. Johansson D, et al. CNS Neurosci Ther. 2018 May;24(5):439-447. doi: 10.1111/cns.12807. Epub 2018 Jan 25. CNS Neurosci Ther. 2018. PMID: 29652438 Free PMC article.

The daily levodopa dose was increased by 15% (112 mg, P < 0.001) from period 1 to 2, and the dose interval was reduced by 12% (22 minutes, P = 0.003). The treatment adherence to LC-5 was high in both periods. The MDS-UPDRS parts II and III, disease-specific quality of l

…

The daily levodopa dose was increased by 15% (112 mg, P < 0.001) from period 1 to 2, and the dose interval was reduced by 12% (22

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Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom.
Hubig L, Sussex AK, MacCulloch A, Hughes D, Graham R, Morris L, Raza S, Lloyd AJ, Sowinski A, Gallop K. Hubig L, et al. J Health Econ Outcomes Res. 2023 Mar 3;10(1):41-50. doi: 10.36469/001c.68157. eCollection 2023. J Health Econ Outcomes Res. 2023. PMID: 36883056 Free PMC article.
Vignettes were finalized following a second round of interviews with individuals living with LOPD and used in health state valuation exercises with people of the UK population. Participants rated the health states using the EQ-5D-5L, visual analogue scale, and time trade-o …
Vignettes were finalized following a second round of interviews with individuals living with LOPD and used in health state valuation exercis …
Comparison of two intravaginal progesterone-releasing devices in shortened-timed artificial insemination protocols in beef cattle.
Zwiefelhofer EM, Macmillan K, Gobikrushanth M, Adams GP, Yang SX, Anzar M, Asai-Coakwell M, Colazo MG. Zwiefelhofer EM, et al. Theriogenology. 2021 Jul 1;168:75-82. doi: 10.1016/j.theriogenology.2021.03.023. Epub 2021 Apr 1. Theriogenology. 2021. PMID: 33862427
In Expt. 3, there was no difference in the ovulatory follicle diameter at device removal (P = 0.22) or TAI (P = 0.28) between P4 groups. Treatment with a PRID tended (P = 0.10) to increase the P/AI in cows compared to a CIDR (73.5% vs. 61.0%). ...
In Expt. 3, there was no difference in the ovulatory follicle diameter at device removal (P = 0.22) or TAI (P = 0.28) between P4 grou …
A Rational Approach To Antitubercular Drug Design: Molecular Docking, Prediction of ADME Properties and Evaluation of Antitubercular Activity of Novel Isonicotinamide Scaffold.
Das P, Gumma SR, Nayak A, Menghani S, Mandhadi JR, Prabhu PP. Das P, et al. Recent Adv Antiinfect Drug Discov. 2024;19(2):148-158. doi: 10.2174/2772434418666230710142852. Recent Adv Antiinfect Drug Discov. 2024. PMID: 37723955
RESULTS: The analysis was based on the binding energy and minimum inhibitory concentration (MIC). The highest and lowest binding energy is -4.22 Kcal/mol (f) and -8.45 Kcal/mol (d), and the MIC for compound d was found to be 644.22 nM. Among all the ligands, compoun …
RESULTS: The analysis was based on the binding energy and minimum inhibitory concentration (MIC). The highest and lowest binding energy is - …
Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.
Wefers J, van Moorsel D, Hansen J, Connell NJ, Havekes B, Hoeks J, van Marken Lichtenbelt WD, Duez H, Phielix E, Kalsbeek A, Boekschoten MV, Hooiveld GJ, Hesselink MKC, Kersten S, Staels B, Scheer FAJL, Schrauwen P. Wefers J, et al. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7789-7794. doi: 10.1073/pnas.1722295115. Epub 2018 Jul 9. Proc Natl Acad Sci U S A. 2018. PMID: 29987027 Free PMC article.
Here, we investigated insulin sensitivity and muscle metabolism in 14 healthy young lean men [age 22.4 2.8 years; body mass index (BMI) 22.3 2.1 kg/m(2) (mean SD)] after a 3-d control protocol and a 3.5-d misalignment protocol induced by a 12-h rapid shift of the be …
Here, we investigated insulin sensitivity and muscle metabolism in 14 healthy young lean men [age 22.4 2.8 years; body mass index (BM …
The chemopreventive effects of orally administered dexamethasone in Strain A/J mice following cessation of smoke exposure.
Witschi H, Espiritu I, Ly M, Uyeminami D. Witschi H, et al. Inhal Toxicol. 2005 Feb;17(2):119-22. doi: 10.1080/08958370590899712. Inhal Toxicol. 2005. PMID: 15764489
Male Strain A/J mice were exposed for 6 mo, 6 h/d, 5d/wk to a mixture of cigarette sidestream and mainstream smoke with an average total suspended particulate concentration of 156 mg/m3. ...
Male Strain A/J mice were exposed for 6 mo, 6 h/d, 5d/wk to a mixture of cigarette sidestream and mainstream smoke with an average to …
Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence.
Cho YJ, Wang H, Kozekov ID, Kozekova A, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Rizzo CJ, Lloyd RS, Stone MP. Cho YJ, et al. Chem Res Toxicol. 2006 Aug;19(8):1019-29. doi: 10.1021/tx0600604. Chem Res Toxicol. 2006. PMID: 16918240
The conformation of the crotonaldehyde-derived N(2)-[3-oxo-1(S)-methyl-propyl]-dG adduct in the oligodeoxynucleotide 5'-d(G(1)C(2)T(3)A(4)G(5)C(6)X(7)A(8)G(9)T(10)C(11)C(12))-3'.5'-d(G(13)G(14)A(15)C(16)T(17)C(18)G(19)C(20)T(21)A(22)G(23)C(2)(4))-3', where X = N(2)-[3-oxo- …
The conformation of the crotonaldehyde-derived N(2)-[3-oxo-1(S)-methyl-propyl]-dG adduct in the oligodeoxynucleotide 5'-d(G(1)C(2)T(3)A(4)G( …