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Diagnosis and Management of Opsoclonus-Myoclonus-Ataxia Syndrome in Children: An International Perspective.
Rossor T, Yeh EA, Khakoo Y, Angelini P, Hemingway C, Irani SR, Schleiermacher G, Santosh P, Lotze T, Dale RC, Deiva K, Hero B, Klein A, de Alarcon P, Gorman MP, Mitchell WG, Lim M; OMS Study Group. Rossor T, et al. Neurol Neuroimmunol Neuroinflamm. 2022 Mar 8;9(3):e1153. doi: 10.1212/NXI.0000000000001153. Print 2022 May. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 35260471 Free PMC article. Review.
BACKGROUND AND OBJECTIVES: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare disorder of the nervous system that classically presents with a combination of characteristic eye movement disorder and myoclonus, in addition to ataxia, irritability, and sleep …
BACKGROUND AND OBJECTIVES: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare disorder of the nervous system that classical …
Immune-mediated Cerebellar Ataxias: Practical Guidelines and Therapeutic Challenges.
Mitoma H, Manto M, Hampe CS. Mitoma H, et al. Curr Neuropharmacol. 2019;17(1):33-58. doi: 10.2174/1570159X16666180917105033. Curr Neuropharmacol. 2019. PMID: 30221603 Free PMC article. Review.
Immune-mediated cerebellar ataxias (IMCAs), a clinical entity reported for the first time in the 1980s, include gluten ataxia (GA), paraneoplastic cerebellar degenerations (PCDs), antiglutamate decarboxylase 65 (GAD) antibody-associated cerebellar ataxia …
Immune-mediated cerebellar ataxias (IMCAs), a clinical entity reported for the first time in the 1980s, include gluten ataxia …
Downbeat nystagmus: a clinical review of diagnosis and management.
Tran TM, Lee MS, McClelland CM. Tran TM, et al. Curr Opin Ophthalmol. 2021 Nov 1;32(6):504-514. doi: 10.1097/ICU.0000000000000802. Curr Opin Ophthalmol. 2021. PMID: 34456290 Review.
In recent years, there is increasing awareness of nonstructural causes of DBN including gluten ataxia, nutritional deficiencies, and paraneoplastic syndromes, among others. Medical management with aminopyridines has become first-line therapy in addition to di …
In recent years, there is increasing awareness of nonstructural causes of DBN including gluten ataxia, nutritional deficiencies, and …
Principles and approaches to the treatment of immune-mediated movement disorders.
Mohammad SS, Dale RC. Mohammad SS, et al. Eur J Paediatr Neurol. 2018 Mar;22(2):292-300. doi: 10.1016/j.ejpn.2017.11.010. Epub 2017 Dec 19. Eur J Paediatr Neurol. 2018. PMID: 29289523 Review.
Immune mediated movement disorders include movement disorders in the context of autoimmune encephalitis such as anti-NMDAR encephalitis, post-infectious autoimmune movement disorders such as Sydenham chorea, paraneoplastic autoimmune movement disord …
Immune mediated movement disorders include movement disorders in the context of autoimmune encephalitis such as anti-NMDAR enc …
Childhood opsoclonus-myoclonus syndrome: diagnosis and treatment.
Blaes F, Dharmalingam B. Blaes F, et al. Expert Rev Neurother. 2016 Jun;16(6):641-8. doi: 10.1080/14737175.2016.1176914. Epub 2016 Apr 27. Expert Rev Neurother. 2016. PMID: 27095464
Opsoclonus-myoclonus syndrome (OMS) is a rare and primarily immune-mediated disease in children and adults. The main symptoms include opsoclonus, myoclonus and ataxia. In children, the symptoms also include irritability, and, over a long-term course, learning …
Opsoclonus-myoclonus syndrome (OMS) is a rare and primarily immune-mediated disease in children and adults. The main symptoms include …
Successful use of tacrolimus for treatment-refractory neuroblastoma-associated opsoclonus-myoclonus-ataxia syndrome: A case series.
Delap S, Shah N, Kuns O, Franklin B, Skeens MA. Delap S, et al. Pediatr Blood Cancer. 2024 Apr;71(4):e30903. doi: 10.1002/pbc.30903. Epub 2024 Feb 6. Pediatr Blood Cancer. 2024. PMID: 38321586
Opsoclonus-myoclonus-ataxia syndrome (OMAS) is an autoimmune central nervous system disorder, primarily manifesting as a paraneoplastic sequalae to neuroblastoma, and characterized by motor disorders and behavioral disturbances. ...We treated three chi …
Opsoclonus-myoclonus-ataxia syndrome (OMAS) is an autoimmune central nervous system disorder, primarily manifesting as a pa …
Treatment and revaccination of children with paraneoplastic opsoclonus-myoclonus-ataxia syndrome and neuroblastoma: The Memorial Sloan Kettering experience.
Patel A, Fischer C, Lin YC, Basu EM, Kushner BH, De Braganca K, Khakoo Y. Patel A, et al. Pediatr Blood Cancer. 2020 Aug;67(8):e28319. doi: 10.1002/pbc.28319. Epub 2020 Jun 15. Pediatr Blood Cancer. 2020. PMID: 32543116 Free PMC article.
OBJECTIVE: To review the treatment and revaccination of neuroblastoma-associated opsoclonus-myoclonus-ataxia syndrome (OMAS) patients at Memorial Sloan Kettering Cancer Center (MSK). ...To date, six patients have been revaccinated at a minimum of 2 years after compl …
OBJECTIVE: To review the treatment and revaccination of neuroblastoma-associated opsoclonus-myoclonus-ataxia syndrome (OMAS) p …
Clinical Presentation, Management, and Diagnostic Performance of 2021 Criteria for Paraneoplastic Neurologic Syndromes in Childhood.
Zhou J, Jin M, Su Y, Zhuo X, Fu L, Ren X, Ren C, Zhou A, Li J, Zhang W. Zhou J, et al. Neurol Neuroimmunol Neuroinflamm. 2024 May;11(3):e200242. doi: 10.1212/NXI.0000000000200242. Epub 2024 Apr 24. Neurol Neuroimmunol Neuroinflamm. 2024. PMID: 38657195 Free article.
BACKGROUND AND OBJECTIVES: Paraneoplastic neurologic syndromes (PNSs) are remote neurologic immune-related effects of tumors. ...In cases of rapidly progressive cerebellar syndrome, a similar therapeutic regimen was used. Nine patients underwent regular follow-ups o …
BACKGROUND AND OBJECTIVES: Paraneoplastic neurologic syndromes (PNSs) are remote neurologic immune-related effects of tumors. ...In c …
Tumors masquerading as neurological diseases: A caution for clinicians in planning diagnosis and treatment.
Vidhya Annapoorni CS, Retnaswami CS, Mailankody P, Katragadda P, Pillai SK, Rangarajan A, Padmanabha H, Pendharkar H. Vidhya Annapoorni CS, et al. Neurol India. 2020 Mar-Apr;68(2):368-372. doi: 10.4103/0028-3886.280647. Neurol India. 2020. PMID: 32415012 Free article.
Toxic, metabolic and nutritional, and immune-mediated consequences of clinically occult neoplasms produce a spectrum of neurological diseases, recognition of which has therapeutic and prognostic importance. PATIENTS AND METHODS: Children, as well as adults who presented to …
Toxic, metabolic and nutritional, and immune-mediated consequences of clinically occult neoplasms produce a spectrum of neurological disease …