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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
2006 2
2007 5
2008 6
2009 3
2010 2
2011 3
2012 2
2013 5
2014 4
2015 2
2016 2
2017 8
2018 5
2019 10
2020 10
2021 7
2022 7
2023 4
2024 1

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81 results

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Page 1
Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators.
Manickam R, Tur J, Badole SL, Chapalamadugu KC, Sinha P, Wang Z, Russ DW, Brotto M, Tipparaju SM. Manickam R, et al. J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1177-1196. doi: 10.1002/jcsm.12887. Epub 2022 Jan 21. J Cachexia Sarcopenia Muscle. 2022. PMID: 35060352 Free PMC article.

RESULTS: Insulin resistance increased 1.6-fold in diabetic mice compared with wild-type mice and after 4 weeks treatment with P7C3 rescued diabetes (P < 0.05). In the db-P7C3 mice fasting blood glucose levels decreased to 0.96-fold compared with C57Bl/6J w

…
RESULTS: Insulin resistance increased 1.6-fold in diabetic mice compared with wild-type mice and after 4 weeks treatment with …
Behavioral neuroscience of psychological pain.
Papini MR, Fuchs PN, Torres C. Papini MR, et al. Neurosci Biobehav Rev. 2015 Jan;48:53-69. doi: 10.1016/j.neubiorev.2014.11.012. Epub 2014 Nov 25. Neurosci Biobehav Rev. 2015. PMID: 25446953 Review.
This review centers on psychological pain as studied in nonhuman animals. After covering issues of terminology, the article briefly discusses the daily-life significance of psychological pain and then centers on a discussion of the results originating from two procedures i …
This review centers on psychological pain as studied in nonhuman animals. After covering issues of terminology, the article briefly d …
NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging.
Wagner S, Manickam R, Brotto M, Tipparaju SM. Wagner S, et al. Mol Cell Biochem. 2022 Jun;477(6):1829-1848. doi: 10.1007/s11010-022-04408-1. Epub 2022 Mar 25. Mol Cell Biochem. 2022. PMID: 35334034 Free PMC article. Review.
NAD(+) repletion ameliorates muscular dystrophy and improves the mitochondrial and muscle stem cell function and thereby increase lifespan in mice. Accordingly, NAD(+) is considered as an anti-oxidant and anti-aging molecule. ...
NAD(+) repletion ameliorates muscular dystrophy and improves the mitochondrial and muscle stem cell function and thereby increase lifespan i …
A latitudinal gradient in thermal transgenerational plasticity and a test of theory.
Munch SB, Lee WS, Walsh M, Hurst T, Wasserman BA, Mangel M, Salinas S. Munch SB, et al. Proc Biol Sci. 2021 May 12;288(1950):20210797. doi: 10.1098/rspb.2021.0797. Epub 2021 May 12. Proc Biol Sci. 2021. PMID: 33975479 Free PMC article.
To do so, we take advantage of the latitudinal decrease in the predictability of temperatures in near shore waters along the US East Coast. Using sheepshead minnows (Cyprinodon variegatus) from South Carolina, Maryland, and Connecticut, we found the first evidence for a la …
To do so, we take advantage of the latitudinal decrease in the predictability of temperatures in near shore waters along the US East Coast. …
Comparative analysis of fat composition in marrow, serum, and muscle from aging C57BL6 mice.
Al Saedi A, Wang Z, Shah A, Brotto M, Duque G. Al Saedi A, et al. Mech Ageing Dev. 2022 Sep;206:111690. doi: 10.1016/j.mad.2022.111690. Epub 2022 Jun 22. Mech Ageing Dev. 2022. PMID: 35752298
Using targeted-lipidomics approach, we comprehensively quantified fat composition (lipid mediators [LMs]) in bone marrow flush, gastrocnemius and serum obtained from 6-, 24- and 42-week-old C57BL6 mice. Compared to young mice (6wks), all tissues in older mice …
Using targeted-lipidomics approach, we comprehensively quantified fat composition (lipid mediators [LMs]) in bone marrow flush, gastrocnemiu …
Identification and Functional Characterization of Metabolites for Bone Mass in Peri- and Postmenopausal Chinese Women.
Gong R, Xiao HM, Zhang YH, Zhao Q, Su KJ, Lin X, Mo CL, Zhang Q, Du YT, Lyu FY, Chen YC, Peng C, Liu HM, Hu SD, Pan DY, Chen Z, Li ZF, Zhou R, Wang XF, Lu JM, Ao ZX, Song YQ, Weng CY, Tian Q, Schiller MR, Papasian CJ, Brotto M, Shen H, Shen J, Deng HW. Gong R, et al. J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3159-e3177. doi: 10.1210/clinem/dgab146. J Clin Endocrinol Metab. 2021. PMID: 33693744 Free PMC article.
Finally, we explored the effects of a novel prominent BMD-associated metabolite on bone metabolism through both in vivo/in vitro experiments. RESULTS: Twenty metabolites and a co-functional metabolite module (consisting of fatty acids) were significantly associated …
Finally, we explored the effects of a novel prominent BMD-associated metabolite on bone metabolism through both in vivo/in vit …
Editorial: Innate Immunity in Early Diverging Metazoans.
Traylor-Knowles N, Browne WE, Mydlarz LD, Palmer CV, Rosental B. Traylor-Knowles N, et al. Front Immunol. 2022 Jan 31;13:816550. doi: 10.3389/fimmu.2022.816550. eCollection 2022. Front Immunol. 2022. PMID: 35173730 Free PMC article. No abstract available.
Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice.
Zheng H, Li Q, Li S, Li Z, Brotto M, Weiss D, Prosdocimo D, Xu C, Reddy A, Puchowicz M, Zhao X, Weitzmann MN, Jain MK, Qu CK. Zheng H, et al. Elife. 2023 Sep 6;12:RP86944. doi: 10.7554/eLife.86944. Elife. 2023. PMID: 37672386 Free PMC article.
Genetically deleting Ptpmt1 in the heart and skeletal muscle of mice showed that while the development of these organs was not affected, mitochondria in these cells switched from using carbohydrates to using fats as an energy source. Over time, this shift damaged both the …
Genetically deleting Ptpmt1 in the heart and skeletal muscle of mice showed that while the development of these organs was not affect …
In vivo MRS measurement of 2-hydroxyglutarate in patient-derived IDH-mutant xenograft mouse models versus glioma patients.
Tiwari V, Mashimo T, An Z, Vemireddy V, Piccirillo S, Askari P, Hulsey KM, Zhang S, de Graaf RA, Patel TR, Pan E, Mickey BE, Maher EA, Bachoo RM, Choi C. Tiwari V, et al. Magn Reson Med. 2020 Sep;84(3):1152-1160. doi: 10.1002/mrm.28183. Epub 2020 Jan 30. Magn Reson Med. 2020. PMID: 32003035 Free PMC article.
A PRESS sequence was tailored at 9.4 T, with computer simulation and phantom analyses, for improving 2HG detection in mice. 2HG and other metabolites in the PDX mice were measured using the optimized MRS at 9.4 T and compared with 3 T MRS measurements of the metabol …
A PRESS sequence was tailored at 9.4 T, with computer simulation and phantom analyses, for improving 2HG detection in mice. 2HG and o …
81 results