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Year Number of Results
1985 1
1989 1
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1999 2
2000 1
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2002 3
2003 4
2004 4
2005 1
2006 2
2007 2
2008 1
2009 3
2010 1
2011 2
2012 5
2013 6
2014 7
2015 9
2016 11
2017 14
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2019 10
2020 17
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2023 13
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143 results

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Page 1
Philadelphia chromosome-like acute lymphoblastic leukemia.
Tasian SK, Loh ML, Hunger SP. Tasian SK, et al. Blood. 2017 Nov 9;130(19):2064-2072. doi: 10.1182/blood-2017-06-743252. Epub 2017 Oct 2. Blood. 2017. PMID: 28972016 Free PMC article. Review.
These alterations can be grouped into major subclasses that include ABL-class fusions involving ABL1, ABL2, CSF1R, and PDGFRB that phenocopy BCR-ABL1 and alterations of CRLF2, JAK2, and EPOR that activate JAK/STAT signaling. ...
These alterations can be grouped into major subclasses that include ABL-class fusions involving ABL1, ABL2, CSF1R, and PDGFRB that ph …
High Expression of ABL2 Suppresses Apoptosis in Gastric Cancer.
Liu Y, Shao C, Zhu L, Jiang S, Li G, Zhang W, Lin Y, Ni Y, Cao H, Shao S. Liu Y, et al. Dig Dis Sci. 2018 Sep;63(9):2294-2300. doi: 10.1007/s10620-018-5111-7. Epub 2018 May 16. Dig Dis Sci. 2018. PMID: 29767389
BACKGROUND: Diseases associated with Abelson-related gene (also called ABL2) include leukemia; furthermore, previous researches have studied the expressions and functions of ABL2 in different types of malignancies and found that it plays an important role in almost …
BACKGROUND: Diseases associated with Abelson-related gene (also called ABL2) include leukemia; furthermore, previous researches have …
BCR-ABL1-like B-Acute Lymphoblastic Leukemia/Lymphoma: A Comprehensive Review.
Jain S, Abraham A. Jain S, et al. Arch Pathol Lab Med. 2020 Feb;144(2):150-155. doi: 10.5858/arpa.2019-0194-RA. Epub 2019 Oct 23. Arch Pathol Lab Med. 2020. PMID: 31644323 Free article. Review.
.-: In the 2016 update of the World Health Organization (WHO) classification of hematopoietic neoplasms, BCR-ABL1-like B-acute lymphoblastic leukemia/lymphoma (B-ALL) is added as a new provisional entity that lacks the BCR-ABL1 translocation but shows a pattern of gene exp …
.-: In the 2016 update of the World Health Organization (WHO) classification of hematopoietic neoplasms, BCR-ABL1-like B-acute lympho …
Bone marrow mesenchymal stem cells-derived exosomal microRNA-19b-1-5p reduces proliferation and raises apoptosis of bladder cancer cells via targeting ABL2.
Fu D, Liu B, Jiang H, Li Z, Fan C, Zang L. Fu D, et al. Genomics. 2021 May;113(3):1338-1348. doi: 10.1016/j.ygeno.2021.03.011. Epub 2021 Mar 17. Genomics. 2021. PMID: 33722655 Free article.
METHODS: miR-19b-1-5p and ABL2 expression were tested in bladder cancer. miR-19b-1-5p inhibition/elevation assays were conducted to determine its role in bladder cancer. ...CONCLUSION: BMSCs-derived exosomal miR-19b-1-5p suppresses bladder cancer growt …
METHODS: miR-19b-1-5p and ABL2 expression were tested in bladder cancer. miR-19b-1-5p inhibition/elevation assays were conduct …
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.
Roberts KG, Li Y, Payne-Turner D, Harvey RC, Yang YL, Pei D, McCastlain K, Ding L, Lu C, Song G, Ma J, Becksfort J, Rusch M, Chen SC, Easton J, Cheng J, Boggs K, Santiago-Morales N, Iacobucci I, Fulton RS, Wen J, Valentine M, Cheng C, Paugh SW, Devidas M, Chen IM, Reshmi S, Smith A, Hedlund E, Gupta P, Nagahawatte P, Wu G, Chen X, Yergeau D, Vadodaria B, Mulder H, Winick NJ, Larsen EC, Carroll WL, Heerema NA, Carroll AJ, Grayson G, Tasian SK, Moore AS, Keller F, Frei-Jones M, Whitlock JA, Raetz EA, White DL, Hughes TP, Guidry Auvil JM, Smith MA, Marcucci G, Bloomfield CD, Mrózek K, Kohlschmidt J, Stock W, Kornblau SM, Konopleva M, Paietta E, Pui CH, Jeha S, Relling MV, Evans WE, Gerhard DS, Gastier-Foster JM, Mardis E, Wilson RK, Loh ML, Downing JR, Hunger SP, Willman CL, Zhang J, Mullighan CG. Roberts KG, et al. N Engl J Med. 2014 Sep 11;371(11):1005-15. doi: 10.1056/NEJMoa1403088. N Engl J Med. 2014. PMID: 25207766 Free PMC article.
Expression of ABL1, ABL2, CSF1R, JAK2, and PDGFRB fusions resulted in cytokine-independent proliferation and activation of phosphorylated STAT5. Cell lines and human leukemic cells expressing ABL1, ABL2, CSF1R, and PDGFRB fusions were sensitive in vitro to dasatinib …
Expression of ABL1, ABL2, CSF1R, JAK2, and PDGFRB fusions resulted in cytokine-independent proliferation and activation of phosphoryl …
miR-20a promotes prostate cancer invasion and migration through targeting ABL2.
Qiang XF, Zhang ZW, Liu Q, Sun N, Pan LL, Shen J, Li T, Yun C, Li H, Shi LH. Qiang XF, et al. J Cell Biochem. 2014 Jul;115(7):1269-76. doi: 10.1002/jcb.24778. J Cell Biochem. 2014. PMID: 24464651
Knockdown of ABL2 promoted cell invasion and migration and we identified miR-20a-induced cell invasion and migration can be rescued by ABL2. In conclusion, our findings show that miR-20a significantly contributes to the progression of prostate cancer by targe …
Knockdown of ABL2 promoted cell invasion and migration and we identified miR-20a-induced cell invasion and migration can be rescued b …
Circ_0000263 facilitates the proliferation and inhibits the apoptosis of cervical cancer depending on the regulation of miR-1179/ABL2 axis.
Zhang Y, Di Q, Chen J, Chang M, Ma Y, Yu J. Zhang Y, et al. Reprod Sci. 2022 Sep;29(9):2636-2646. doi: 10.1007/s43032-022-00920-3. Epub 2022 Mar 30. Reprod Sci. 2022. PMID: 35355231
Circ_0000263 served as a sponge for miR-1179, and miR-1179 inhibitor reversed the regulation of si-circ_0000263 on CC cell proliferation and apoptosis. ABL2 could be targeted by miR-1179, and circ_0000263 could sponge miR-1179 to regulate ABL2. Overexpression of …
Circ_0000263 served as a sponge for miR-1179, and miR-1179 inhibitor reversed the regulation of si-circ_0000263 on CC cell proliferation and …
Circular RNA circPGD contributes to gastric cancer progression via the sponging miR-16-5p/ABL2 axis and encodes a novel PGD-219aa protein.
Liu Y, Cao J, Zhu L, Zhao W, Zhou Y, Shao C, Shao S. Liu Y, et al. Cell Death Discov. 2022 Sep 14;8(1):384. doi: 10.1038/s41420-022-01177-0. Cell Death Discov. 2022. PMID: 36104322 Free PMC article.
CircRNAs have critical effects on tumor development and progression. However, circPGD effect on gastric cancer (GC) is still elusive. Nuclear and cytoplasmic RNA fractionation, and RNA-FISH assay examined the localization of circPGD in MGC-803 cells. qRT-PCR was conducted …
CircRNAs have critical effects on tumor development and progression. However, circPGD effect on gastric cancer (GC) is still elusive. …
ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination.
Jones JK, Zhang H, Lyne AM, Cavalli FMG, Hassen WE, Stevenson K, Kornahrens R, Yang Y, Li S, Dell S, Reitman ZJ, Herndon JE 2nd, Hoj J, Pendergast AM, Thompson EM. Jones JK, et al. Neurooncol Adv. 2023 Aug 7;5(1):vdad095. doi: 10.1093/noajnl/vdad095. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37781087 Free PMC article.
The biological mechanisms underlying LMD are unclear. The Abelson (ABL) tyrosine kinase family members, ABL1 and ABL2, have been implicated in cancer cell migration, invasion, adhesion, metastasis, and chemotherapy resistance, and are upstream mediators of the oncog …
The biological mechanisms underlying LMD are unclear. The Abelson (ABL) tyrosine kinase family members, ABL1 and ABL2, have been impl …
Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL.
Lahera A, Vela-Martín L, López-Nieva P, Salgado RN, Rodríguez-Perales S, Torres-Ruiz R, López-Lorenzo JL, Cornago J, Llamas P, Fernández-Navarro P, Sánchez-Domínguez R, Segovia JC, Sastre I, Cobos-Fernández MÁ, Menéndez P, Santos J, Fernández-Piqueras J, Villa-Morales M. Lahera A, et al. Br J Haematol. 2023 Aug;202(3):693-698. doi: 10.1111/bjh.18901. Epub 2023 Jun 2. Br J Haematol. 2023. PMID: 37264982 No abstract available.
143 results